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Alamar Biosciences and the German Center for Neurodegenerative Diseases (DZNE) partner for Landmark Proteomic Profiling study in the Rhineland Study Cohort

Business

Alamar Biosciences and the German Center for Neurodegenerative Diseases (DZNE) partner for Landmark Proteomic Profiling study in the Rhineland Study Cohort
Business

Business

Alamar Biosciences and the German Center for Neurodegenerative Diseases (DZNE) partner for Landmark Proteomic Profiling study in the Rhineland Study Cohort

2025-07-29 21:12 Last Updated At:21:45

NULISAseq™ CNS Disease Panel 120 and Inflammation Panel 250 to Power Biomarker Discovery in 23,000 Longitudinal Samples

FREMONT, Calif., July 29, 2025 /PRNewswire/ -- Alamar Biosciences, a company powering precision proteomics to enable the earliest detection of disease, today announced a strategic collaboration with the German Center for Neurodegenerative Diseases (DZNE) to deploy its ultra-sensitive NULISAseq™ CNS Disease Panel 120 and Inflammation Panel 250 in the Rhineland Study—one of the world's most comprehensive and innovative longitudinal aging cohorts, as well as in some of the DZNE's clinical disease specific cohorts. This initiative will profile 23,000 plasma samples to accelerate biomarker discovery and advance understanding of healthy aging and neurodegeneration.

"Understanding aging and dementia requires both advanced technology and deeply characterized cohorts," said Prof. Monique Breteler, Director of Population Health Sciences at DZNE and Principal Investigator of the Rhineland Study. "Integrating Alamar's multiplex panels into our research opens new opportunities to decode the molecular signatures of brain aging."

The DZNE Rhineland Study is an ongoing, large-scale population-based cohort designed to investigate determinants of healthy aging and the development of neurodegenerative diseases across the lifespan. By utilizing Alamar's NULISAseq CNS Disease Panel 120, researchers will be able to measure hundreds of brain-related proteins from minimal blood volumes, with exceptional sensitivity and specificity. Notably, the CNS panel's ability to distinguish brain-derived phosphorylated tau from total phosphorylated tau in plasma represents a transformative advance for early detection and risk stratification of neurodegenerative conditions such as Alzheimer's disease. In addition, the NULISAseq Inflammation Panel 250 provides the most comprehensive and sensitive profiling of immune-related proteins implicated in aging and neuroinflammation associated with neurodegenerative diseases.

The resulting proteomic data will be combined with the study's extensive clinical, demographic, and imaging datasets, enabling researchers to track protein changes over time, identify early biomarkers, and support the development of precision diagnostics and targeted therapies.

"This partnership marks a major step forward in aging and dementia research," said Yuling Luo, PhD, Founder, Chairman and CEO of Alamar Biosciences. "With NULISA's unmatched sensitivity and the depth of the DZNE Rhineland Study, we can uncover novel protein biomarkers that reveal the trajectories of cognitive health and disease progression in aging populations."

This collaboration reflects a shared commitment to scientific rigor, inclusivity, and innovation in neurodegenerative disease research. By capturing diverse aging trajectories in a deeply characterized population, Alamar and DZNE aim to drive earlier diagnosis, improved prognosis, and new therapeutic pathways for age-related brain disorders.

About the DZNE Rhineland Study

The DZNE (German Center for Neurodegenerative Diseases) Rhineland Study is an ambitious, population-based cohort following thousands of individuals across decades to uncover determinants of healthy aging and neurodegeneration. Detailed clinical, imaging, genetic, and lifestyle data are collected and harmonized to enable deep insights into the aging brain. Learn more about the DZNE at www.dzne.de/en/, and about the DZNE Rhineland Study at www.rheinland-studie.de/en/ 

About Alamar Biosciences, Inc.

Alamar Biosciences is a privately held life sciences company with a mission to power precision proteomics to enable the earliest detection of disease. The company's proprietary NULISA Platform along with the ARGO HT System work seamlessly with the latest advances in genomics to achieve single digit attomolar detection sensitivity, greatly surpassing the most sensitive protein detection technology on the market today. For more information, please visit alamarbio.com

 

** The press release content is from PR Newswire. Bastille Post is not involved in its creation. **

Alamar Biosciences and the German Center for Neurodegenerative Diseases (DZNE) partner for Landmark Proteomic Profiling study in the Rhineland Study Cohort

Alamar Biosciences and the German Center for Neurodegenerative Diseases (DZNE) partner for Landmark Proteomic Profiling study in the Rhineland Study Cohort

Alamar Biosciences and the German Center for Neurodegenerative Diseases (DZNE) partner for Landmark Proteomic Profiling study in the Rhineland Study Cohort

Alamar Biosciences and the German Center for Neurodegenerative Diseases (DZNE) partner for Landmark Proteomic Profiling study in the Rhineland Study Cohort

SINGAPORE, Jan. 16, 2026 /PRNewswire/ -- Coda, a global leader in digital content monetization, today announced that it is integrating Unity's In‑App Purchasing (IAP) SDK with Coda's global web store platforms. This collaboration offers developers a single place to manage and optimize their entire digital catalog across mobile, web, and PC - directly through Unity's existing IAP workflow. 

With just a few lines of code, developers can launch secure, branded web stores powered by Coda - offering players more ways to purchase securely while improving their margins.

The integration is powered by Coda's Merchant of Record (MoR) solution, which is already trusted by leading publishers and fast-growing studios worldwide. As the legal seller in each market, Coda manages payments, fraud prevention, tax remittance, invoicing, and compliance across more than 70 markets and over 400 payment methods. This gives developers more time to focus on the game and the player experience.

"As the games industry moves beyond closed ecosystems, developers of every size want more flexibility and control over how they grow," said Shane Happach, CEO of Coda. "Our integration with Unity's IAP SDK gives creators more choice in how they launch and operate their own stores, wherever their players are, minus the complexity of managing global payments or compliance. This reflects Coda's commitment to democratizing game development and helping every studio, large or small, succeed on their own terms."

As web-based purchasing becomes a more practical part of developers' business mix, interest in direct-to-consumer web stores continues to grow. Today, these channels already account for roughly 26% of mobile gaming revenue in East and Southeast Asia, according to research from Niko Partners and Coda.

First-party web stores give developers greater control over pricing, promotions, and player communication, but introduce operational complexity across payments, compliance, fraud, and support. Coda removes these barriers with a scalable payments and risk platform, integrated directly into Unity's workflow.

Coda's integration with Unity's IAP sets a new D2C standard by bringing out-of-app monetization into developers' existing workflows, removing operational complexity, and making it easier to run web stores at a global scale.

Learn more at coda.co.

About Coda

Coda is a global leader in digital content monetization and distribution. We're trusted by 300+ publishers—including Activision, Electronic Arts, and Riot Games—to grow their audiences and revenue worldwide. Our out-of-app solutions include Custom Commerce, a fully customizable web store; Codapay, which enables seamless direct payments through a single API integration on publishers' websites; Codashop, the go-to marketplace for millions of gamers to purchase in-game content; and Distribution, which extends content reach through a network of trusted commerce partners. Founded in 2011, Coda is headquartered in Singapore with a team of 550+ Codans around the globe. Coda recently acquired Recharge, Europe's leading prepaid payments platform.  Coda is backed by Apis Partners, Insight Partners, and Smash Capital, and has been named an APAC High Growth Company (2023) by Financial Times, one of Granite Asia's NextGenTech 30 (2024), a payments leader on Fortune's Fintech Innovation Asia list (2024), and listed among The Straits Times Fastest Growing Fintechs (2024). For more on Coda, visit coda.co.

Press Contacts
Coda:
Liz Adam — VP, Corporate Affairs
elizah.adam@coda.co

** The press release content is from PR Newswire. Bastille Post is not involved in its creation. **

Coda and Unity to enable out-of-app monetization for game developers globally

Coda and Unity to enable out-of-app monetization for game developers globally

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