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Evolv Launches With First-Ever Oral Biomimetic Supplement to Deliver GLP-1 Naturally

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Evolv Launches With First-Ever Oral Biomimetic Supplement to Deliver GLP-1 Naturally
News

News

Evolv Launches With First-Ever Oral Biomimetic Supplement to Deliver GLP-1 Naturally

2025-09-03 21:01 Last Updated At:21:20

SAN FRANCISCO--(BUSINESS WIRE)--Sep 3, 2025--

Evolv, a biomimetics company redefining longevity and well-being through nature-powered science, publicly launched today with the debut of its inaugural product: Evolv GLP-1. The first-of-its-kind, oral GLP-1 supplement was created using a proprietary yeast strain engineered to produce a new molecule that delivers the full power of GLP-1 naturally. This breakthrough, non-habituating supplement is designed to help people take control of their appetite, metabolism, and long-term wellness—without side effects or barriers to access.

This press release features multimedia. View the full release here: https://www.businesswire.com/news/home/20250903111371/en/

“GLP-1 is a natural hormone found in your body that helps signal fullness and satiety. We've created a product that mimics the effects of GLP-1, helping you feel fuller longer, and allowing you to approach your nutrition and food choices with a sense of calm intention, rather than impulsive craving,” said Becca McCarthy, MBA, co-founder, president, and chief operating officer of Evolv. “This isn’t just another supplement. We’re building a new category at the intersection of biology and accessibility to reimagine how people take control of their metabolism, appetite, and longevity with solutions that deliver real results and work with the body—not against it.”

Biomimetics: The Next Frontier in Wellness

With the introduction of Evolv GLP-1, the company unveils a new category of health technology: biomimetics. Biomimetics are biologically engineered molecules designed to mimic and enhance the natural functions of the human body. Unlike synthetic compounds, these molecules recreate the body’s natural processes using food-safe organisms from nature and are free of stimulants and habit-forming ingredients, and unwanted side effects.

Evolv’s biomimetics are possible due to a world-class team of scientists and bioengineers with deep expertise in synthetic biology, molecular design, and therapeutic innovation leveraging AI-driven molecular modeling. Led by Co-Founder and Chief Technology Officer Kwang-Chul Kwon, PhD, and Cory Henderson, PhD, the science team also includes Christina Bergey, PhD, assistant professor of genetics at Rutgers University, and Justin Smith, PhD, founder of Recombia Bioscience.

The Current GLP-1 Market Was Built for Disease. Evolv Was Built for You.

More than 73% of adults in the U.S. are overweight, and over 40 million have turned to synthetic GLP-1 drugs for answers. In recent years, GLP-1 prescriptions have increased by over 400% for those suffering from chronic disease and also those eager to explore the promise they offer for metabolic health. Yet half of adults have trouble affording these solutions, and millions suffer adverse side effects due to the drugs’ synthetic simulation of GLP-1 at extreme doses.

As the public metabolic health crisis rises and demand for solutions grows, Evolv is changing the status quo with a radically different approach. Unlike traditional supplements, Evolv GLP-1 provides lasting appetite control, reduced food noise, and enhanced metabolic function to support steady energy and satiety all day long. By balancing hunger signals, improving digestion, and optimizing nutrient absorption, Evolv GLP-1 is the solution for healthy individuals seeking an effective weight management solution, not designed for the treatment of disease.

“We've created a new version of our body's own GLP-1 that can withstand digestion, be absorbed from a pill, and promote the body’s natural signaling pathways responsible for appetite and metabolic function with no eligibility barriers,” said Cory Henderson, PhD,co-founder and chief executive officerat Evolv. “It’s a molecular breakthrough that can transform how we support metabolic health and opens the door to a whole new era of efficacious biologics.”

A Next-Gen Formula Rooted in Nature

Evolv GLP-1 contains a single active ingredient, EV1 Peptide, composed solely of canonical amino acids. This application leverages cutting-edge genetic engineering to modify a proprietary yeast powder, derived from yeast hydrolysate, which is clinically demonstrated to activate the body’s natural GLP-1 production. Developed by leading bioengineers and scientists, Evolv GLP-1 works in alignment with normal digestive processes and is manufactured using food-safe ingredients.

Unlike many supplements that are not bioavailable–low absorption–and use artificial fillers, Evolv GLP-1 is natural, vegan, and allergen-free. The formula is designed to include only purposeful, high-quality ingredients that ensure optimal effectiveness, bioavailability, and seamless integration into any dietary lifestyle.

Evolv GLP-1 is manufactured in the USA in a cGMP-compliant facility and formulated under all applicable FDA guidelines. Each batch undergoes third-party testing to ensure purity, potency, and safety. To date, three studies have been completed on the Evolv GLP-1 formulation, with a fourth clinical trial currently underway. These studies have measured both safety and efficacy across key biomarkers related to appetite regulation, metabolic function, and nutrient absorption.

Evolving the Human Experience

Evolv GLP-1 is the first of many biomimetic supplements in the company’s pipeline that will provide natural solutions for key health needs. Evolv plans to apply its proprietary technology to areas such as hair health and restoration, among other focuses.

Evolv GLP-1 is available exclusively on evolvlife.com. Follow the brand on Instagram to join the movement and unlock the future of your wellness on your terms.

About Evolv

Evolv is a molecular health company pioneering biomimetics and the next generation of nature-powered wellness solutions. Built at the intersection of public health and consumer innovation, Evolv formulates effective, natural, and accessible solutions that activate the body’s natural pathways for metabolic, hormonal, and long-term wellbeing. The company’s flagship product, Evolv GLP-1, is the first oral supplement to deliver the full power of GLP-1 naturally. With a focus on efficacy, accessibility, and longevity, Evolv is shaping the future of wellness innovation. Learn more at evolvlife.com.

Evolv GLP-1’s formula naturally activates the body's GLP-1 production to support weight loss and healthy blood glucose levels (Photo credit: Paris Tilley)

Evolv GLP-1’s formula naturally activates the body's GLP-1 production to support weight loss and healthy blood glucose levels (Photo credit: Paris Tilley)

ANCHORAGE, Alaska (AP) — A state appeals court is being asked to dismiss felony voter misconduct charges against an Alaska resident born in American Samoa, one of numerous cases that have drawn attention to the complex citizenship status of people born in the U.S. territory.

In arguments Thursday, attorneys for Tupe Smith plan to ask the Alaska Court of Appeals in Anchorage to reverse a lower court's decision that let stand the indictment brought against her. Her supporters say she made an innocent mistake that does not merit charges, but the state contends Smith falsely and deliberately claimed citizenship.

Prosecutors also have brought charges against 10 other people from American Samoa in the small Alaska community of Whittier, including Smith’s husband and her mother-in-law. American Samoa is the only U.S. territory where residents are not automatically granted citizenship by being born on American soil and instead are considered U.S. nationals. Paths to citizenship exist, such as naturalization, though that process can be expensive and cumbersome.

American Samoans can serve in the military, obtain U.S. passports and vote in elections in American Samoa, but they cannot hold public office in the U.S. or participate in most U.S. elections.

About 25 people gathered on a snowy street outside the courthouse before Thursday's hearing to support Smith. One woman, Fran Seager of Palmer, held a sign that said, “Support our Samoans. They are US nationals.”

Smith's husband, Michael Pese, thanked the American Samoa community in the Anchorage area. “If it wasn’t for you guys, I wouldn’t be strong enough to face this head on,” he said.

State Sen. Forrest Dunbar, a Democrat who attended the rally, said the Alaska Department of Law has limited resources.

“We should be going after people who are genuine criminals, who are violent criminals, or at least have the intent to deceive,” he said. “I do not think it is a good use of our limited state resources to go after these hardworking, taxpaying Alaskans who are not criminals.”

Smith was arrested after winning election to a regional school board in 2023. She said she relied on erroneous information from local election officials when she identified herself as a U.S. citizen on voter registration forms.

In a court filing in 2024, one of her previous attorneys said that when Smith answered questions from the Alaska state trooper who arrested her, she said she was aware that she could not vote in presidential elections but was “unaware of any other restrictions on her ability to vote.”

Smith said she marks herself as a U.S. national on paperwork. But when there was no such option on voter registration forms, she was told by city representatives that it was appropriate to mark U.S. citizen, according to the filing.

Smith “exercised what she believed was her right to vote in a local election. She did so without any intent to mislead or deceive anyone,” her current attorneys said in a filing in September. “Her belief that U.S. nationals may vote in local elections, which was supported by advice from City of Whittier election officials, was simply mistaken.”

The state has said Smith falsely and deliberately claimed citizenship. Prosecutors pointed to the language on the voter application forms she filled out in 2020 and 2022, which explicitly said that if the applicant was not at least 18 years old and a U.S. citizen, “do not complete this form, as you are not eligible to vote.”

The counts Smith was indicted on “did not have anything to do with her belief in her ability to vote in certain elections; rather they concerned the straightforward question of whether or not Smith intentionally and falsely swore she was a United States citizen,” Kayla Doyle, an assistant attorney general, said in court filings last year.

One of Smith's attorneys, Neil Weare, co-founder of the Washington-based Right to Democracy Project, said by email last week that if the appeals court lets stand the indictment, Alaska will be “the only state to our knowledge with such a low bar for felony voter fraud.”

Bohrer reported from Juneau, Alaska.

Michael Pese and his wife, Tupe Smith, stand outside the Boney Courthouse in Anchorage, Alaska, Thursday, Jan. 15, 2026, ahead of the Alaska Court of Appeals hearing a challenge to the voter fraud case brought against her by the state. (AP Photo/Mark Thiessen)

Michael Pese and his wife, Tupe Smith, stand outside the Boney Courthouse in Anchorage, Alaska, Thursday, Jan. 15, 2026, ahead of the Alaska Court of Appeals hearing a challenge to the voter fraud case brought against her by the state. (AP Photo/Mark Thiessen)

Michael Pese, left, his wife, Tupe Smith, and their son Maximus pose for a photo outside the Boney Courthouse in Anchorage, Alaska, Thursday, Jan. 15, 2026, ahead of the Alaska Court of Appeals hearing a challenge to the voter fraud case brought against her by the state. (AP Photo/Mark Thiessen)

Michael Pese, left, his wife, Tupe Smith, and their son Maximus pose for a photo outside the Boney Courthouse in Anchorage, Alaska, Thursday, Jan. 15, 2026, ahead of the Alaska Court of Appeals hearing a challenge to the voter fraud case brought against her by the state. (AP Photo/Mark Thiessen)

FILE - Tupe Smith poses for a photo outside the school in Whittier, Alaska, May 13, 2025. (AP Photo/Mark Thiessen, File)

FILE - Tupe Smith poses for a photo outside the school in Whittier, Alaska, May 13, 2025. (AP Photo/Mark Thiessen, File)

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