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Brian Thomas Jr. comes up big late as the Jaguars send the Texans to 0-3 with a 17-10 victory

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Brian Thomas Jr. comes up big late as the Jaguars send the Texans to 0-3 with a 17-10 victory
Sport

Sport

Brian Thomas Jr. comes up big late as the Jaguars send the Texans to 0-3 with a 17-10 victory

2025-09-22 06:01 Last Updated At:06:21

JACKSONVILLE, Fla. (AP) — Brian Thomas Jr. was so frustrated by his latest drop — and the ensuing boos — that he slammed his helmet into the ground near the bench.

A few minutes later, he hurled a football at a wall to celebrate one of the biggest plays of the day.

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Jacksonville Jaguars wide receiver Brian Thomas Jr., right, holds the ball after making a catch as Houston Texans cornerback Kamari Lassiter tries to push him out of bounds during the second half of an NFL football game Sunday, Sept. 21, 2025, in Jacksonville, Fla. (AP Photo/John Raoux)

Jacksonville Jaguars wide receiver Brian Thomas Jr., right, holds the ball after making a catch as Houston Texans cornerback Kamari Lassiter tries to push him out of bounds during the second half of an NFL football game Sunday, Sept. 21, 2025, in Jacksonville, Fla. (AP Photo/John Raoux)

Jacksonville Jaguars cornerback Jourdan Lewis (2) reacts after intercepting a pass by Houston Texans quarterback CJ. Stroud, not visible, during the second half of an NFL football game Sunday, Sept. 21, 2025, in Jacksonville, Fla. (AP Photo/Phelan M. Ebenhack)

Jacksonville Jaguars cornerback Jourdan Lewis (2) reacts after intercepting a pass by Houston Texans quarterback CJ. Stroud, not visible, during the second half of an NFL football game Sunday, Sept. 21, 2025, in Jacksonville, Fla. (AP Photo/Phelan M. Ebenhack)

Jacksonville Jaguars wide receiver Travis Hunter, right, tries to avoid a tackle by Houston Texans linebacker Henry To'Oto'O after making a catch during the second half of an NFL football game Sunday, Sept. 21, 2025, in Jacksonville, Fla. (AP Photo/Phelan M. Ebenhack)

Jacksonville Jaguars wide receiver Travis Hunter, right, tries to avoid a tackle by Houston Texans linebacker Henry To'Oto'O after making a catch during the second half of an NFL football game Sunday, Sept. 21, 2025, in Jacksonville, Fla. (AP Photo/Phelan M. Ebenhack)

Houston Texans safety Jalen Pitre (5) intercepts a pass intended for Jacksonville Jaguars wide receiver Parker Washington, center, as teammate cornerback Kamari Lassiter (4) helps defend during the second half of an NFL football game Sunday, Sept. 21, 2025, in Jacksonville, Fla. (AP Photo/Phelan M. Ebenhack)

Houston Texans safety Jalen Pitre (5) intercepts a pass intended for Jacksonville Jaguars wide receiver Parker Washington, center, as teammate cornerback Kamari Lassiter (4) helps defend during the second half of an NFL football game Sunday, Sept. 21, 2025, in Jacksonville, Fla. (AP Photo/Phelan M. Ebenhack)

Houston Texans wide receiver Nico Collins, front, fumbles the ball after taking a hit from Jacksonville Jaguars cornerback Tyson Campbell during the second half of an NFL football game Sunday, Sept. 21, 2025, in Jacksonville, Fla. (AP Photo/Phelan M. Ebenhack)

Houston Texans wide receiver Nico Collins, front, fumbles the ball after taking a hit from Jacksonville Jaguars cornerback Tyson Campbell during the second half of an NFL football game Sunday, Sept. 21, 2025, in Jacksonville, Fla. (AP Photo/Phelan M. Ebenhack)

Jacksonville Jaguars linebacker Devin Lloyd, left, collects a fumble by Houston Texans wide receiver Nico Collins, right, during the second half of an NFL football game Sunday, Sept. 21, 2025, in Jacksonville, Fla. (AP Photo/Phelan M. Ebenhack)

Jacksonville Jaguars linebacker Devin Lloyd, left, collects a fumble by Houston Texans wide receiver Nico Collins, right, during the second half of an NFL football game Sunday, Sept. 21, 2025, in Jacksonville, Fla. (AP Photo/Phelan M. Ebenhack)

Trevor Lawrence found Thomas for a 46-yard gain, Travis Etienne scored on the next play and the Jacksonville Jaguars held on to beat the Houston Texans 17-10 in a chippy divisional game Sunday.

“I just had to keep fighting,” said Thomas, who also dropped passes in each of the first two games. “A 60-minute game is a long game, and my teammates had my back the whole game. Everything is not going to go your way the whole time. You keep fighting, and that’s what happens when you keep fighting.”

It was Jacksonville's first home win against the Texans since 2017. Houston had won 12 of the previous 14 in the AFC South series.

Equally important for the Jaguars (2-1) was the way Thomas responded to another mistake-filled performance. His 46-yarder against an all-out blitz came after three drops and may have been the catalyst needed to turn around a sluggish start.

The Texans (0-3) seemingly let Etienne score from 10 yards out with 1:48 remaining.

C.J. Stroud drove Houston into striking distance in the waning seconds. But Josh Hines-Allen slapped the ball as the quarterback released it, and Antonio Johnson intercepted the wobbler to seal the victory.

It was the kind of closeout that has eluded the Jaguars in recent years.

“We're not going to get bullied,” said Lawrence, who had to be pulled away from Texans linebacker Azeez Al-Shaair in the second half. “I feel like that's what they want to do. I'm not saying that's wrong, but that's their mindset and it's not going to happen to this team. It was fun to be able to punch back and stand up in those moments, where it's like, ‘All right, you want to throw that punch? We’re here.'”

The Texans will point to Nico Collins' fumble with 3:58 to play as the turning point. Tyson Campbell knocked the ball out after a catch and it bounced into Devin Lloyd's hands. It got Jacksonville headed in the right direction.

“We give the ball to one of our best players, Nico,” Texans coach DeMeco Ryans said. "We trust him with the football. He knows it. I know he hates it more than anyone else, to have the ball taken away from him there. That was tough.”

Stroud's picks were his first against the Jaguars. The third-year pro entered the game with seven TD passes and no interceptions in four starts against the Jaguars. But the Jaguars dominated this matchup.

Stroud completed 25 of 38 passes for 204 yards, with a touchdown and the two turnovers. He also was sacked twice.

Jacksonville finished with three takeaways for the third consecutive game, the first time that's happened to start a season.

“You turn the ball over three times, it's tough to win in this league," Ryans said. "It’s tough enough to win, but when you put yourself in the position to help the opponent win, that’s just not winning football.”

Hines-Allen dominated his matchup with Houston rookie left tackle Aireontae Ersery. Not only did Hines-Allen start the game-sealing play, he finished with three QB hits, including a shared sack with Arik Armstead.

Ersery, a second-round draft pick from Minnesota, allowed the sack, several pressures and was flagged for holding. He also was penalized 15 yards for grabbing Campbell’s facemask during a running play.

“We're building something very special here,” Hines-Allen said. “This was a great building point for how far can we go.”

Hines-Allen is two sacks shy of breaking the franchise record (55) set by Tony Brackens in 2003. Hines-Allen has 53 ½ career sacks over seven seasons.

Texans All-Pro cornerback Derek Stingley Jr. left the game in the first quarter with an abdominal injury. He returned for the next series but ended up leaving the game for good. He was ruled out early in the second half. Safety C.J. Gardner-Johnson left the game briefly in the third but returned.

Jaguars receiver Dyami Brown injured his left shoulder while making a 1-yard catch in the third, ended up in the locker room and was later ruled out.

Houston hosts Tennessee on Sunday.

Jacksonville plays at San Francisco on Sunday. The Jaguars are 0-2 in San Francisco.

AP NFL: https://apnews.com/hub/nfl

Jacksonville Jaguars wide receiver Brian Thomas Jr., right, holds the ball after making a catch as Houston Texans cornerback Kamari Lassiter tries to push him out of bounds during the second half of an NFL football game Sunday, Sept. 21, 2025, in Jacksonville, Fla. (AP Photo/John Raoux)

Jacksonville Jaguars wide receiver Brian Thomas Jr., right, holds the ball after making a catch as Houston Texans cornerback Kamari Lassiter tries to push him out of bounds during the second half of an NFL football game Sunday, Sept. 21, 2025, in Jacksonville, Fla. (AP Photo/John Raoux)

Jacksonville Jaguars cornerback Jourdan Lewis (2) reacts after intercepting a pass by Houston Texans quarterback CJ. Stroud, not visible, during the second half of an NFL football game Sunday, Sept. 21, 2025, in Jacksonville, Fla. (AP Photo/Phelan M. Ebenhack)

Jacksonville Jaguars cornerback Jourdan Lewis (2) reacts after intercepting a pass by Houston Texans quarterback CJ. Stroud, not visible, during the second half of an NFL football game Sunday, Sept. 21, 2025, in Jacksonville, Fla. (AP Photo/Phelan M. Ebenhack)

Jacksonville Jaguars wide receiver Travis Hunter, right, tries to avoid a tackle by Houston Texans linebacker Henry To'Oto'O after making a catch during the second half of an NFL football game Sunday, Sept. 21, 2025, in Jacksonville, Fla. (AP Photo/Phelan M. Ebenhack)

Jacksonville Jaguars wide receiver Travis Hunter, right, tries to avoid a tackle by Houston Texans linebacker Henry To'Oto'O after making a catch during the second half of an NFL football game Sunday, Sept. 21, 2025, in Jacksonville, Fla. (AP Photo/Phelan M. Ebenhack)

Houston Texans safety Jalen Pitre (5) intercepts a pass intended for Jacksonville Jaguars wide receiver Parker Washington, center, as teammate cornerback Kamari Lassiter (4) helps defend during the second half of an NFL football game Sunday, Sept. 21, 2025, in Jacksonville, Fla. (AP Photo/Phelan M. Ebenhack)

Houston Texans safety Jalen Pitre (5) intercepts a pass intended for Jacksonville Jaguars wide receiver Parker Washington, center, as teammate cornerback Kamari Lassiter (4) helps defend during the second half of an NFL football game Sunday, Sept. 21, 2025, in Jacksonville, Fla. (AP Photo/Phelan M. Ebenhack)

Houston Texans wide receiver Nico Collins, front, fumbles the ball after taking a hit from Jacksonville Jaguars cornerback Tyson Campbell during the second half of an NFL football game Sunday, Sept. 21, 2025, in Jacksonville, Fla. (AP Photo/Phelan M. Ebenhack)

Houston Texans wide receiver Nico Collins, front, fumbles the ball after taking a hit from Jacksonville Jaguars cornerback Tyson Campbell during the second half of an NFL football game Sunday, Sept. 21, 2025, in Jacksonville, Fla. (AP Photo/Phelan M. Ebenhack)

Jacksonville Jaguars linebacker Devin Lloyd, left, collects a fumble by Houston Texans wide receiver Nico Collins, right, during the second half of an NFL football game Sunday, Sept. 21, 2025, in Jacksonville, Fla. (AP Photo/Phelan M. Ebenhack)

Jacksonville Jaguars linebacker Devin Lloyd, left, collects a fumble by Houston Texans wide receiver Nico Collins, right, during the second half of an NFL football game Sunday, Sept. 21, 2025, in Jacksonville, Fla. (AP Photo/Phelan M. Ebenhack)

NEWARK, Del.--(BUSINESS WIRE)--Jan 15, 2026--

QPS Holdings, LLC (QPS), an award-winning contract research organization (CRO) focused on bioanalysis and clinical trials announces the successful implementation of Oracle Argus, a premier pharmacovigilance system designed to support comprehensive safety case management for clinical trials.

This press release features multimedia. View the full release here: https://www.businesswire.com/news/home/20260115711485/en/

The adoption of the Oracle Argus drug safety platform underscores QPS’s commitment to advancing patient safety, regulatory compliance, and operational excellence across its clients’ clinical drug development programs. Integrating this industry-standard safety platform strengthens QPS’ ability to capture, manage, and report adverse events in accordance with global regulatory requirements.

“Ensuring patient safety and data integrity is at the heart of what we do when conducting clinical trials,” said Derek Grimes, Executive Vice President of QPS. “Oracle Argus provides us with a robust, scalable solution to support the growing needs of our customer’s clinical trial portfolios and the evolving expectations of regulatory authorities worldwide.”

“Oracle Argus provides QPS Holdings, LLC with a trusted, globally recognized drug safety platform that supports compliance with stringent pharmacovigilance standards and regulations, while streamlining end-to-end safety operations and insights at scale,” said Seema Verma, executive vice president and general manager, Oracle Health and Life Sciences. “With our industry-leading solutions, QPS Holdings, LLC can further transform and elevate its safety case management for customers worldwide.”

The deployment of Oracle Argus will enable QPS to:

As the demand for innovative therapies continues to rise, CROs play a critical role in managing both development speed and patient safety. By leveraging the Oracle Argus platform, QPS is well-positioned to deliver on its mission to accelerate pharmaceutical breakthroughs across the globe by delivering custom-built research services.

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ABOUT QPS HOLDINGS, LLC

QPS is a global, full-service, GLP/GCP-compliant contract research organization (CRO) delivering the highest grade of discovery, bioanalysis, preclinical and clinical drug development services. Since 1995, QPS has grown from a small bioanalysis shop into a full-service CRO with 1,200+ employees in the US, Europe, Asia and India. Today, QPS offers expanded pharmaceutical contract R&D services with special expertise in pharmacology, DMPK, toxicology, bioanalysis, translational medicine, PBMC processing, central safety labs, clinical trials, and clinical research services. An award-winning leader focused on bioanalysis and clinical trials, QPS is known for proven quality standards, technical expertise, a flexible approach to research, client satisfaction, turnkey laboratories, Phase I/II clinical units, and multi-site clinical research services. For more information, visit http://www.qps.com or email info@qps.com.

ABOUT ORACLE ARGUS

Oracle Argus is an industry-leading, trusted solution for processing, analyzing, and reporting adverse event cases originating in pre-market and post-market drugs, biologics, vaccines, devices, and combination products. Oracle has been a Leader in the IDC MarketScape: Worldwide Life Science R&D Pharmacovigilance Technology Solutions and Consulting Services 2025 Vendor Assessment (doc # US53669225, July 2025). To learn more about Oracle’s pharmacovigilance portfolio visit: https://www.oracle.com/life-sciences/safety-solutions/argus-safety-case-management/. Trademarks: Oracle, Java, MySQL and NetSuite are registered trademarks of Oracle Corporation.

Derek Grimes, EVP, Global Head of Clinical Research at QPS Holdings, LLC.

Derek Grimes, EVP, Global Head of Clinical Research at QPS Holdings, LLC.

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