Five months after ending development of its own obesity treatment, Pfizer is accelerating its push into the rapidly growing field with a nearly $5 billion acquisition.
The COVID-19 vaccine and treatment maker said Monday that it will pay $47.50 in cash for each share of development-stage drugmaker Metsera. That represents a premium of more than 42% to Metsera’s closing price Friday.
Pfizer also could pay an additional $22.50 per share depending on how Metsera’s product pipeline develops.
Metsera Inc. has no products on the market, but its pipeline includes four programs in clinical development and one in mid-stage testing. Pfizer said the deal will add expertise and potential oral and injectable treatments.
Pfizer CEO Albert Bourla noted in a statement from the drugmaker that there are more than 200 health conditions associated with obesity, which he called “a large and growing space.”
Demand for obesity treatments has soared in recent years, due to unprecedented weight loss provided by regular injections of market leaders Wegovy from Novo Nordisk and Eli Lilly and Co.'s Zepbound. The Lilly drug generated $5.7 billion in sales in the first half of the year.
But the drugs can cost patients hundreds of dollars a month, and experts in the field are looking for competition to potentially drive down prices.
Pfizer currently has no obesity treatments on the market but has some in clinical development. Earlier this year, the company said it was ending development of a potential once-daily pill treatment before it started late-stage testing, the biggest and most expensive phase of clinical development.
Pfizer said the boards of both New York-based companies have approved the deal, but Metsera shareholders still need to OK it. The companies expect the acquisition to close in this year's fourth quarter. It still needs approval from regulators.
Shares of Pfizer Inc. climbed 38 cents to $24.40 before markets opened Monday while Metsera's stock advanced about 61%.
FILE - The Pfizer logo is displayed at the company's headquarters, Friday, Feb. 5, 2021, in New York. (AP Photo/Mark Lennihan, File)
JOHANNESBURG (AP) — Torrential rains and flooding have killed more than 100 people in South Africa, Mozambique and Zimbabwe, and authorities warned Friday that more severe weather was expected across several countries in southern Africa.
South Africa has reported at least 19 deaths in two of its northern provinces following heavy rains that began last month and led to severe flooding.
Tourists and staff members were evacuated this week by helicopter from flooded camps to other areas in the renowned Kruger National Park, which is closed to visitors while parts of it are inaccessible because of washed out roads and bridges, South Africa's national parks agency said.
In neighboring Mozambique, the Institute for Disaster Management and Risk Reduction said 103 people had died in an unusually severe rainy season since late last year. Those deaths were from various causes including electrocution from lightning strikes, drowning in floods, infrastructure collapse caused by the severe weather and cholera, the institute said.
The worst flooding in Mozambique has been in the central and southern regions, where more than 200,000 people have been affected, thousands of homes have been damaged, while tens of thousands face evacuation, the World Food Program said.
Zimbabwe’s disaster management agency said that 70 people have died and more than 1,000 homes have been destroyed in heavy rains since the beginning of the year, while infrastructure including schools, roads and bridges collapsed.
Flooding has also hit the island nation of Madagascar off the coast of Africa as well as Malawi and Zambia. Authorities in Madagascar said 11 people died in floods since late November.
The United States' Famine Early Warning System said flooding was reported or expected in at least seven southern African nations, possibly due to the presence of the La Nina weather phenomenon that can bring heavy rains to parts of southeastern Africa.
South African President Cyril Ramaphosa visited flood-stricken areas in the northern Limpopo province on Thursday and said that region had received around 400 millimeters (more than 15 inches) of rain in less than a week. He said that in one district he visited “there are 36 houses that have just been wiped away from the face of the Earth. Everything is gone ... the roofs, the walls, the fences, everything.”
The flooding occurred in the Limpopo and Mpumalanaga provinces in the north, and the South African Weather Service issued a red-level 10 alert for parts of the country for Friday, warning of more heavy rain and flooding that poses a threat to lives and could cause widespread infrastructure damage.
The huge Kruger wildlife park, which covers some 22,000 square kilometers (7,722 square miles) across the Limpopo and Mpumalanga provinces, has been impacted by severe flooding and around 600 tourists and staff members have been evacuated from camps to high-lying areas in the park, Kruger National Park spokesperson Reynold Thakhuli said.
He couldn't immediately say how many people there were in the park, which has been closed to visitors after several rivers burst their banks and flooded camps, restaurants and other areas. The parks agency said precautions were being taken and no deaths or injuries had been reported at Kruger.
The South African army sent helicopters to rescue other people trapped on the roofs of their houses or in trees in northern parts of the country, it said. An army helicopter also rescued border post officers and police officers stranded at a flooded checkpoint on the South Africa-Zimbabwe border.
Southern Africa has experienced a series of extreme weather events in recent years, including devastating cyclones and a scorching drought that caused a food crisis in parts of a region that often suffers food shortages.
The World Food Program said more than 70,000 hectares (about 173,000 acres) of crops in Mozambique, including staples such as rice and corn, have been waterlogged in the current flooding, worsening food insecurity for thousands of small-scale farmers who rely on their harvests for food.
Imray reported from Cape Town, South Africa. AP writers Charles Mangwiro in Maputo, Mozambique, and Farai Mutsaka in Harare, Zimbabwe, contributed to this report.
AP Africa news: https://apnews.com/hub/africa
This image made from video shows the scene after flooding in Tete Province, Mozambique, Thursday, Jan. 15, 2026. (AP Photo)
This image made from video shows the scene after flooding in Tete Province, Mozambique, Thursday, Jan. 15, 2026. (AP Photo)
This image made from video shows the scene after flooding in Tete Province, Mozambique, Thursday, Jan. 15, 2026. (AP Photo)
