A list of this year's Nobel Prize winners

STOCKHOLM (AP) — The announcement Monday that three laureates will share the Nobel memorial prize in economics for explaining innovation-driven growth brings this year's Nobel awards to a close.

All but the Nobel Peace Prize, which was announced on Friday in the Norwegian capital, Oslo, are announced in Stockholm. The award ceremonies will be held on Dec. 10, the anniversary of the death of Alfred Nobel, who founded the prizes.

Here are this year's winners:

On Oct. 6, the Nobel Prize in medicine was awarded to three scientists for their work on the immune system.

Mary E. Brunkow, Fred Ramsdell and Dr. Shimon Sakaguchi uncovered a key pathway the body uses to keep the immune system in check, viewed as critical to understanding autoimmune diseases such as Type 1 diabetes, rheumatoid arthritis and lupus.

In separate projects, the trio identified the importance of what are now called regulatory T cells. Scientists are using those findings in a variety of ways: to discover better treatments for autoimmune diseases, to improve organ transplant success and to enhance the body’s own fight against cancer, among others.

Brunkow, 64, is now a senior program manager at the Institute for Systems Biology in Seattle. Ramsdell, 64, is a scientific adviser for San Francisco-based Sonoma Biotherapeutics. Sakaguchi, 74, is a distinguished professor at the Immunology Frontier Research Center at Osaka University in Japan.

On Oct. 7, the Nobel Prize in physics was awarded to another trio of scientists for their research on the “weirdness” of subatomic particles called quantum tunneling. That has enabled the ultrasensitive measurements achieved by MRI machines and laid the groundwork for better cellphones and faster computers.

The work by John Clarke, Michel H. Devoret and John M. Martinis took the seeming contradictions of the subatomic world — where light can be both a wave and a particle, and parts of atoms can tunnel through seemingly impenetrable barriers — and applied them in the more traditional physics of digital devices. The results of their findings are just starting to appear in advanced technology and could pave the way for the development of supercharged computing.

Clarke, 83, conducted his research at the University of California, Berkeley; Martinis, 67, at the University of California, Santa Barbara; and Devoret, 72, is at Yale and also at the University of California, Santa Barbara. Clarke spearheaded the project.

On Oct. 8, another scientific trio won the Nobel Prize in chemistry for their development of new molecular structures that can trap vast quantities of gas inside. Experts say the work lays the groundwork to potentially suck greenhouse gases out of the atmosphere or harvest moisture from desert environments.

Experts say the work of Susumu Kitagawa, Richard Robson and Omar M. Yaghi “may contribute to solving some of humankind’s greatest challenges.”

Kitagawa, 74, is with Japan’s Kyoto University, while Robson, 88, is affiliated with the University of Melbourne in Australia. Yaghi, 60, is with the University of California, Berkeley.

On Oct. 9, Hungarian writer László Krasznahorkai won the Nobel Prize in literature for work the judges said upholds the power of art in the midst of “apocalyptic terror.” His surreal and anarchic novels combine a bleak world view with mordant humor.

Krasznahorkai, 71, has written more than 20 books, including “The Melancholy of Resistance,” a surreal, disturbing tale involving a traveling circus and a stuffed whale, and “Baron Wenckheim’s Homecoming,” the sprawling saga of a gambling-addicted aristocrat.

Krasznahorkai has been a vocal critic of autocratic Hungarian Prime Minister Viktor Orbán, especially his government’s lack of support for Ukraine after Russia launched an all-out war.

On Oct. 10, María Corina Machado of Venezuela won the Nobel Peace Prize, and was lauded for being a “key, unifying figure in a political opposition that was once deeply divided.”

Machado, who turned 58 this week, was set to run against President Nicolás Maduro in last year’s presidential election, but the government disqualified her. The lead-up to the election saw widespread repression, including disqualifications, arrests and human rights violations. Maduro’s government has routinely targeted its real or perceived opponents.

Machado went into hiding and hasn't been seen in public since January, and as a result it's unclear whether she will attend the awards ceremony in Stockholm in December.

Machado becomes the 20th woman to win the Nobel Peace Prize, of the 112 individuals who have been honored.

On Oct. 13, Joel Mokyr, Philippe Aghion and Peter Howitt won the Nobel memorial prize in economics. They were honored for their research into the impact of innovation on economic growth and how new technologies replace older ones, a key economic concept known as “creative destruction.”

The winners represent contrasting but complementary approaches to economics. Mokyr is an economic historian who delved into long-term trends using historical sources, while Howitt and Aghion relied on mathematics to explain how creative destruction works.

Dutch-born Mokyr, 79, is from Northwestern University; Aghion, 69, from the Collège de France and the London School of Economics; and Canadian-born Howitt, 79, from Brown University.

John Clarke sits in his Berkeley, Calif., home after becoming one of the three scientists to win the Nobel Prize in Physics, Tuesday, Oct. 7, 2025. (AP Photo/Noah Berger)

Professofr Susumu Kitagawa speaks at a press conference at Kyoto University in Kyoto, western Japan Thrusday, Oct. 9, 2025, a day after he was awarded the Nobel Prize in chemistry. (Kai Naito/Kyodo News via AP)

FILE - Hungary's Laszlo Krasznahorkai poses for photographers in London, Tuesday, May 19, 2015. (AP Photo/Matt Dunham, File)

FILE - Maria Corina Machado leads a protest against the reelection of President Nicolás Maduro one month after the disputed presidential vote which she claims the opposition won by a landslide, in Caracas, Venezuela, Wednesday, Aug. 28, 2024. (AP Photo/Cristian Hernandez, File)

FILE - A Nobel Prize medal is displayed before a ceremony at the Swedish Ambassador's Residence in London, Monday, Dec. 6, 2021. (AP Photo/Matt Dunham, File)

WASHINGTON (AP) — In New York City, two men who federal authorities say were inspired by the Islamic State brought powerful homemade bombs to a far-right protest outside the mayoral mansion.

In Michigan, a naturalized citizen from Lebanon rammed his vehicle into a synagogue, where he was shot at by security before he shot himself to death.

In Virginia, a man previously imprisoned on a terrorism conviction was heard yelling “Allahu akbar” before opening fire in a university classroom in an attack that officials said ended when the shooter was killed by students.

The three acts of violence in the last week have laid bare a heightened terrorism threat unfolding against the backdrop of the U.S. war with Iran and as the country's counterterrorism system is strained by the departures of experienced national security professionals at the FBI and Justice Department. The firings and resignations, along with the diversion of resources and personnel over the last year to meet other Trump administration priorities, have fueled concerns about the capability to head off a potential surge in threats.

“So much experience has been decimated from the ranks,” said Frank Montoya, a retired senior FBI official. “The folks that were best positioned to get to the bottom of it before something really bad happened” are in many cases no longer with the government, he said, meaning less experienced personnel assigned to the threat are “starting from way behind.”

The FBI said it would not comment on personnel numbers and decisions, but issued a statement saying “agents and staff are dedicated professionals working around the clock to defend the homeland and crush violent crime. The FBI continuously assesses and realigns our resources to ensure the safety of the American people.”

Iran has vowed revenge for the killing by the U.S. and Israel of Supreme Leader Ayatollah Ali Khamenei, and though the fighting has so far been confined to the Middle East, the Islamic Republic has long professed its determination to carry out violence on American soil.

Iranian operatives, for instance, responded to the 2020 assassination of Gen. Qassem Soleimani during the first Trump administration with a disrupted murder-for-hire plot targeting former national security adviser John Bolton.

A Pakistani business owner who says he was carrying out instructions from a contact in Iran's paramilitary Revolutionary Guard was convicted in New York last week of trying to hire hit men in 2024 for assassination plots targeting public figures, including President Donald Trump, who was then running for president.

Though much attention has focused on Iran's use of proxies or hired hands to carry out plots, the country's capability to organize a large-scale assault on the U.S. remains unclear despite clear angst over the potential. The FBI warned in a recent bulletin to law enforcement about Iran’s aspiration to conduct a drone attack targeting California, but after the warning was publicized, officials emphasized the intelligence was unverified and that no specific plot was known to exist.

The U.S. government after the Sept. 11, 2001, attacks overhauled its intelligence and national security apparatus to prevent similarly catastrophic events. But in the years since, lone actors radicalized online have nonetheless carried out shootings like the 2015 ambush attacks at a pair of military sites in Chattanooga, Tennessee and a rampage at an Orlando nightclub the following year by a gunman who killed 49 people and raged against the “filthy ways of the west.”

Those plots by self-directed individuals have proved notoriously difficult to prevent and have occurred even when the FBI has not been roiled by firings and internal upheaval like during the first year of the Trump administration.

“They're self-directed,” said retired FBI official Edward Herbst. “That’s what makes them really lethal. You never know when they're going to rise up. You never know when and where they're going to attack.”

Terrorism concerns typically rise during times of international conflict when military action overseas is accompanied by increased vigilance, including outreach from agents to their sources, more active sharing of tips between federal and local law enforcement and closer coordination among FBI joint terrorism task forces, said Claire Moravec, a former FBI national security official who served as deputy homeland security adviser in Illinois.

Officials have said there is no indication that either the men arrested in connection with the explosives in New York, or the man responsible for Thursday’s Old Dominion University shooting, were motivated explicitly by the Iran war. The man who crashed into Temple Israel synagogue near Detroit on Thursday lost four family members in an Israeli airstrike in his native Lebanon last week, an official in Lebanon said.

Regardless, wars like the one in Iran can function as “accelerants,” raising the volume and intensity of grievances for the disaffected, Moravec said.

“Ultimately, the goal during these periods is not ‘surveillance’ but maintaining a broad awareness of how international events could translate into domestic security risks, so that threats can be identified and disrupted early,” she said in an email.

The Justice Department's National Security Division was established in 2006 to address threats of terrorism, espionage and other concerns. In the last year, lawyers in the division found themselves assigned to review the Jeffrey Epstein files to prepare them for release, and elite sections dedicated to prosecuting terrorists and catching spies have endured turnover.

About half of the division's counterterrorism prosecutors have left since the beginning of the Trump administration, along with about a third of its senior leadership, according to estimates from Justice Connection, a network of department alumni.

A Justice Department spokesperson said the division's singular focus remains “keeping the American people safe from threats foreign and domestic” and that there are no known or credible threats to the homeland.

FBI Director Kash Patel has fired dozens of agents, most recently about a dozen employees who worked on the counterintelligence investigation into Trump's retention of classified documents at his Mar-a-Lago estate in Florida.

“This is not an exaggeration to say that they are not as capable as they were a year and a half ago,” Matthew Olsen, who led the National Security Division during the Biden administration, said this week on the Lawfare podcast, adding that “they’ve lost, forced out, fired, the most capable, the most experienced FBI agents, FBI officials and DOJ prosecutors, that were working on the Iran threat.”

In the national security realm, where experience and source development are vital, the loss of institutional knowledge and community relationships can be a crushing blow, said Montoya, the former FBI official.

“There was no transition,” Montoya said of the agents who have been abruptly fired. “These guys were just walked out of the building. The new guys can call them and say, ‘Hey, can you tell me what you were doing?’” but even so, “you're still introducing a brand new face into the equation.”

FBI Director Kash Patel takes part in a U.S. Hostage and Wrongful Detainee Flag Raising ceremony at the State Department, Monday, March 9, 2026 in Washington. (AP Photo/Kevin Wolf)

NYPD officers stand outside Carl Schurz Park as they investigate suspicious device, Tuesday, March 10, 2026, in New York. (AP Photo/Yuki Iwamura)

Police arrive outside Old Dominion University's campus after reports of an active shooter on Thursday, March 12, 2026, in Norfolk, Va. (AP Photo/John Clark)

Police tape hangs outside the Temple Israel synagogue Friday, March 13, 2026, in West Bloomfield Township, Mich. (AP Photo/Paul Sancya)