MEMPHIS, Tenn.--(BUSINESS WIRE)--Oct 30, 2025--
This holiday season, the stars are shining for St. Jude Children’s Research Hospital ®. The 22nd annual St. Jude Thanks and Giving® campaign is back, unifying celebrities, brands, and shoppers to support efforts by St. Jude to help more children survive cancer and other life-threatening diseases.
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Drew Barrymore, Luis Fonsi, Jon Hamm, Michael Strahan, and Sofia Vergara are joining forces once again to celebrate the spirit of giving. These longtime champions of St. Jude are encouraging everyone to make a difference, whether by donating in-store or online, or by shopping exclusive, limited-edition items from top retailers.
This modern-day tradition continues the legacy of entertainer Danny Thomas, who rallied the power of celebrity to found St. Jude. Today, his children Marlo, Tony and Terre Thomas, carry that torch high with the support of stars and everyday champions.
“The St. Jude Thanks and Giving campaign is more than a fundraiser, it’s a celebration of hope, compassion, and a shared commitment to my father’s dream: that no child should die in the dawn of life,” said Marlo Thomas, National Outreach Director for St. Jude Children’s Research Hospital. “Today, that dream has grown into a global movement to save lives everywhere - around the globe and around the corner from you. And it’s made possible by our generous donors, dedicated partners, and wonderful celebrity friends. That generosity fuels hope. It powers discovery. It brings healing to children around the world.”
Celebrity Voices Inspire Hope and Action
“It’s a true privilege to join forces with St. Jude,” said Drew Barrymore. “Its mission holds a special place in my heart and I’m proud to lend my voice to a cause that brings comfort and hope to families facing cancer and other life-threatening diseases. St. Jude stands for compassion, innovation, and unwavering care for children during their most challenging times. I invite everyone to join me in bringing joy, strength, and healing to the brave children and families of St. Jude.”
“St. Jude Children’s Research Hospital holds a very special place in my heart, and I’m honored to be a part of the St. Jude Thanks and Giving campaign for the 14th year,” said Sofia Vergara. “I’ve met so many brave children and their families throughout the years and the care St. Jude gives to them is extraordinary. St. Jude changes lives not just in the United States, but around the world. I am honored to be part of this mission, and I encourage everyone to join me in supporting St. Jude.”
“For more than 60 years, St. Jude has built a powerful community of doctors, researchers, and supporters united by a singular mission: to help end childhood cancer,” said Jon Hamm. “That is one of the greatest goals for mankind. Being part of the St. Jude Thanks and Giving campaign allows each of us to contribute to something truly impactful for the children of St. Jude and their families, and for the future we all share.”
“I first visited St. Jude Children’s Research Hospital in 2010, and I’ve been all in ever since,” said Michael Strahan. “St. Jude is a place of hope, healing, and heart. Supporting St. Jude is one of the most meaningful things I’ve ever done, and being a part of the St. Jude Thanks and Giving campaign gives us all a chance to make a real difference in the lives of these children and their families.”
“I’m incredibly proud to have been part of the St. Jude family for more than 17 years and I knew from day one I’d always be involved, whether through my voice or my presence,” said Luis Fonsi. “St. Jude is not just a hospital; it’s a research center that shares its breakthroughs around the world. St. Jude transforms lives, bringing hope to children, so growing up becomes a reality. Together, we can give children a second chance at life.”
Brands Unite for St. Jude
Many leading brands and some of the most respected companies in the country come together to support the lifesaving mission of St. Jude during the holidays by joining the St. Jude Thanks and Giving campaign. The tremendous support of our corporate, retail and media partners enable St Jude to continue its lifesaving work.
Brands participating this year include Domino's, Chili’s, Kay Jewelers, HomeGoods, AutoZone, Williams Sonoma, Dollar General, Wingstop, J. Crew Factory, Kia, Marshalls, The Melting Pot, DXL Big + Tall, PayPal, Zales, Jared the Galleria of Jewelry, and TUMI, among others, with MSIG USA joining for the first time.
“For 22 years, the St. Jude Thanks and Giving campaign has turned the spirit of the season into a movement of generosity and impact,” said Ike Anand, President and CEO of ALSAC, the fundraising and awareness organization for St. Jude. “Every donation helps fuel research breakthroughs and compassionate care for kids who need it most. With supporters and countless donors, St. Jude is giving children everywhere the chance to dream big, grow, and celebrate more holidays with their families.”
“Domino’s is proud to continue its long-standing tradition of participating in the St. Jude Thanks and Giving campaign,” said Joe Jordan, Domino’s chief operating officer and president – U.S. “Every child deserves to live their best life, and we’re grateful to be able to provide customers with ways to give charitably, while ordering the pizza they love. Thanks to the generosity of Domino’s customers, we know we can help make a difference.”
Ways to support St. Jude this giving season:
Funds raised help ensure that families never receive a bill from St. Jude for treatment, travel, housing, or food ― so they can focus on helping their child live.
In the Media
The fundraising efforts for the St Jude Thanks and Giving campaign are reinforced with a national blitz of digital, print, television, radio, online, social media, movie theater, and outdoor advertising. This effort is further bolstered by television appearances with Marlo Thomas and St Jude patients on network and talk shows.
Audiences nationwide can tune in to NBC’s TODAY, where St. Jude will be featured the Monday before Thanksgiving and each day that week, with special segments featuring St. Jude patients’ stories of hope, inspiration and survivorship.
Explore the many ways to give back to the children of St. Jude this holiday season.
St. Jude Children’s Research Hospital®: St. Jude Children’s Research Hospital is leading the way the world understands, treats and defeats childhood cancer and other life-threatening diseases. Its purpose is clear: Finding cures. Saving children.® It is the only National Cancer Institute-designated Comprehensive Cancer Center devoted solely to children. When St. Jude opened in 1962, childhood cancer was largely considered incurable. Since then, St. Jude has helped push the overall survival rate from 20% to more than 80% in the United States, and it won't stop until no child dies from cancer. St. Jude shares the breakthroughs it makes to help doctors and researchers at local hospitals and cancer centers around the world improve the quality of treatment and care for even more children. Because of generous donors, families never receive a bill from St. Jude for treatment, travel, housing or food, so they can focus on helping their child live. Visit St. Jude Inspire to discover powerful St. Jude stories of hope, strength, love and kindness. Support the St. Jude mission by donating at stjude.org, liking St. Jude on Facebook, following St. Jude on X, Instagram, LinkedIn and TikTok, and subscribing to its YouTube channel.
Marlo Thomas, National Outreach Director for St. Jude Children’s Research Hospital with St. Jude patients
