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Novo cuts Wegovy prices, but doctors still see cost challenges for patients

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Novo cuts Wegovy prices, but doctors still see cost challenges for patients
News

News

Novo cuts Wegovy prices, but doctors still see cost challenges for patients

2025-11-17 22:47 Last Updated At:11-18 15:24

Novo Nordisk is chopping prices again for Wegovy, but doctors say the expense will remain challenging for patients without insurance.

The drugmaker said Monday that it has started selling higher doses of the injectable obesity treatment for $349 a month to patients paying the full bill. That’s down from $499, and in line with terms of a drug pricing agreement outlined earlier this month by President Donald Trump’s administration.

Novo also started a temporary offer of $199 a month for the first two months of low doses of Wegovy and the drug’s counterpart for diabetes, Ozempic. The new pricing will be available at pharmacies nationwide, through home delivery and from some telemedicine providers.

Rival Eli Lilly also plans price breaks for its weight-loss drug Zepbound once it gets a new, multi-dose pen on the market. Lilly has said it will sell a starter dose of Zepbound for $299 a month and additional doses at up to $449. Both represent $50 reductions from current prices for sales directly to patients.

Obesity treatments like Zepbound and Wegovy have soared in popularity in recent years. Known as GLP-1 receptor agonists, the drugs work by targeting hormones in the gut and brain that affect appetite and feelings of fullness.

In clinical trials, they helped people shed 15% to 22% of their body weight — up to 50 pounds or more in many cases. But affordability has been a persistent challenge for patients.

A recent poll by the nonprofit KFF found that about half of the people who take the treatments say it was hard to afford them.

Both Lilly and Novo announced price cuts earlier this year that brought the cost of higher doses of their treatments down to around $500 a month.

Previous research has shown that people have difficulty paying for a medication when the cost rises above $100 per month, said Stacie Dusetzina, a Vanderbilt University Medical Center professor and prescription drug pricing expert.

She said Novo's new prices are “not going to really move the needle for a person who doesn’t have a pretty reasonable amount of disposable income.”

Dr. Laura Davisson said the medication would still be unaffordable for patients on Medicaid in states where the government-funded program for people with low incomes doesn’t cover the drug.

The bigger issue is expanding coverage of the treatments, said Davisson, a West Virginia University obesity specialist.

“We’ve had hundreds of people lose coverage over the last couple of years, and we keep seeing more and more insurers drop coverage,” she said, adding that her practice has started a group support program to help those who have lost coverage.

Coverage is slated to improve starting next year for at least one big payer under a deal announced by the Trump administration. The federally funded Medicare program, mainly for people ages 65 and older, will begin covering the treatments for people who have severe obesity and others who are overweight or obese and have serious health problems.

Those who qualify will pay $50 copays for the medicine.

Administration officials also said lower prices for the drugs that they negotiated for Medicare also will be provided for Medicaid programs.

That will help expand coverage, according to Dave Moore, Novo's executive vice president for U.S. operations. He said Medicaid programs in 20 states cover the drug for obesity.

Novo officials expect around 40 million more Americans will gain access to their drug through coverage expansions for Medicaid and Medicare.

Neither Moore nor representatives for Eli Lilly would say whether they plan additional price cuts. Both companies also are seeking approval of pill versions of the drugs, which would come with new prices.

Lilly spokesperson Courtney Kasinger said the company believes obesity treatments should be covered just like those for any other chronic condition.

“We're going to continue to work to improve coverage as much as we can across all channels, all stakeholders,” she said.

The Associated Press Health and Science Department receives support from the Howard Hughes Medical Institute’s Department of Science Education and the Robert Wood Johnson Foundation. The AP is solely responsible for all content.

FILE - Boxes for the medications Wegovy and Zepbound are arranged for a photograph in California on May 8, 2025. (AP Photo/JoNel Aleccia, File)

FILE - Boxes for the medications Wegovy and Zepbound are arranged for a photograph in California on May 8, 2025. (AP Photo/JoNel Aleccia, File)

Novo Nordisk President and CEO Mike Doustdar speaks during an event about drug prices with President Donald Trump, Thursday, Nov. 6, 2025, in the Oval Office of the White House in Washington. (AP Photo/Evan Vucci)

Novo Nordisk President and CEO Mike Doustdar speaks during an event about drug prices with President Donald Trump, Thursday, Nov. 6, 2025, in the Oval Office of the White House in Washington. (AP Photo/Evan Vucci)

Novo Nordisk President and CEO Mike Doustdar speaks during an event about drug prices with President Donald Trump, Thursday, Nov. 6, 2025, in the Oval Office of the White House in Washington. (AP Photo/Evan Vucci)

Novo Nordisk President and CEO Mike Doustdar speaks during an event about drug prices with President Donald Trump, Thursday, Nov. 6, 2025, in the Oval Office of the White House in Washington. (AP Photo/Evan Vucci)

維也納--(BUSINESS WIRE)--十二月 8, 2025--

(美國商業資訊)-- AOP Health持續推進其在骨髓增生性腫瘤(一類特殊且罕見的血液腫瘤)領域的臨床研發計畫。這家專注於罕見疾病治療的公司,於2025年在美國佛羅里達州奧蘭多舉行的第67 屆美國血液學會(American Society of Hematology, ASH)年會上,發布了兩項科學研究成果,將為治療策略帶來新的見解。

本新聞稿包含多媒體資訊。完整新聞稿請見此: https://www.businesswire.com/news/home/20251207103807/zh-HK/

ROP-ET與BESREMI PASS

其中一項臨床研究ROP-ET,探討Ropeginterferon alfa-2b在 原發性血小板增多症 (ET)患者中的使用情況。ET是一種由於體內產生的血小板過多而引發的疾病。此試驗為一項前瞻性、多中心、單組第III期臨床研究,評估Ropeginterferon alfa-2b在無法接受現有細胞減量治療 1 的ET患者中的安全性與療效。

另一項研究為BESREMI-PASS研究,旨在觀察該藥物在 原發性紅血球增多症 (PV)患者日常臨床治療中的效果。PV是一種罕見的血液幹細胞癌症,起源於骨髓造血幹細胞,會導致紅血球、白血球及血小板長期異常增多。

致力於滿足尚未被滿足的醫療需求

上述兩項研究,皆為Ropeginterferon α-2b在協助慢性血癌患者治療方面提供了新的見解。

AOP Health執行長Martin Steinhart總結道: 「AOP Health創立的初衷,正是為了回應罕見疾病領域中尚未被滿足的患者需求。我們對研發的持續投入,正體現了這項承諾,並帶來了新的研究成果。我們很榮幸能在ASH年會上,與全球科學界分享這些發現。」

關於Ropeginterferon alfa-2b

Ropeginterferon alfa-2b為全球首個獲准用於治療真性紅血球增多症(MPN)的干擾素藥物。依據歐盟核准內容,該藥物可作為單一療法,用於治療未出現脾腫大症狀的成人真性紅血球增多症患者。

Ropeginterferon alfa-2b屬於長效單聚乙二醇化脯氨酸干擾素(ATC:L03AB15)。初始治療階段為每兩週給藥一次,待血液學指標穩定後,可延長至每四週給藥一次。藥品採用預充式注射筆設計,供患者進行皮下注射使用。

關於AOP Health

AOP Orphan Pharmaceuticals GmbH (「AOP Health」)為一家跨國企業集團,根植於奧地利,集團總部亦設於此。自1996年成立以來,AOP Health Group持續致力於開發創新治療方案,以回應尚未被滿足的醫療需求,重點聚焦於罕見疾病與重症醫學領域。作為整合式治療方案的國際先驅,AOP Health Group透過子公司、代表處及強大的合作夥伴網路,在全球多地開展業務。秉持「需求、科學、信任」的核心理念,AOP Health Group強調對科研的長期承諾,並重視與醫療專業人士及病友組織的合作,確保關鍵利害關係人的需求能貫穿於公司各項行動之中。(aop-health.com)

1 Kiladjian JJ、Marin FF、Al-Ali HK等。ROP-ET:一項評估Ropeginterferon α-2b在治療選擇有限之原發性血小板增多症患者中有效性與安全性的前瞻性第III期臨床試驗。《血液學年鑑》,2024年3月4日:1–2。

需求、科學、信任。(Needs. Science. Trust.)
AOP Orphan Pharmaceuticals GmbH
AOP Health Group成員

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CONTACT: 深入咨詢

DI Isolde Fally

Isolde.Fally@aop-health.com

+43-676-500 4048

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INDUSTRY KEYWORD: SCIENCE BIOTECHNOLOGY RESEARCH PHARMACEUTICAL ONCOLOGY GENERAL HEALTH HEALTH CLINICAL TRIALS

SOURCE: AOP Health

Copyright Business Wire 2025.

PUB: 12/08/2025 12:14 AM/DISC: 12/08/2025 12:15 AM

http://www.businesswire.com/news/home/20251207103807/zh

AOP Health執行長Martin Steinhart博士;圖片來源:AOP Health/Studio Koekart

AOP Health執行長Martin Steinhart博士;圖片來源:AOP Health/Studio Koekart

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