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Chinese researchers complete 2nd successful case in invasive brain-computer interface trial in Shanghai

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Chinese researchers complete 2nd successful case in invasive brain-computer interface trial in Shanghai

2025-12-19 01:45 Last Updated At:02:17

Researchers from the Center for Excellence in Brain Science and Intelligence Technology (CEBSIT) under the Chinese Academy of Sciences (CAS) have made new progress in invasive brain-computer interface clinical trials, with the second successful case involving a paralyzed patient.

According to the research team, the patient suffered a spinal cord injury in 2022 that resulted in high paraplegia. After more than a year of rehabilitation, only head and neck movement was possible. In June this year, the patient underwent implantation of a BCI system.

Following two to three weeks of training, the patient was able to control electronic devices such as a computer cursor and a tablet. To meet further needs, researchers expanded the application from two-dimensional digital screens to three-dimensional physical devices. An intelligent wheelchair and a robotic dog became new control targets.

This shift required the system to not only decode simple intentions such as "left" or "right," but also to deliver continuous, stable, and low-latency precise control to cope with complex real-world environments and interactive tasks.

According to an expert, as the patient became more proficient, the level of mental concentration required was significantly reduced.

"The experience is very close to how we normally control our own bodies. Once you are very skilled, it doesn't require much mental effort -- just like being able to chat while driving," said Zhao Zhengtuo, researcher from CEBSIT.

To achieve this, the team made multiple technical breakthroughs.

At the data source level, they developed high-compression, high-fidelity neural data compression technology and innovatively combined different compression methods. This allows effective information to be extracted efficiently even in noisy neural signal environments, improving overall brain-control performance by 15 to 20 percent.

The team also replaced traditional calibration methods with an "online recalibration" technology that silently and continuously fine-tunes decoding parameters in real time to maintain high system performance. Control speed has also been significantly improved, with intentions and actions now almost synchronized.

Notably, the research team has partnered with a local federation for persons with disabilities to enable the patient who can control a computer via the BCI to participate in online data annotation work, such as verifying the accuracy of AI recognition in vending machines. This makes the patient China's first paraplegic to earn income through labor using a brain-computer interface.

Researchers revealed that a third patient has now had a BCI implanted for nearly two months. Future applications will focus on more refined movements.

"[The next step is] to use the intention of finger movements to control robotic fingers to interact with the external world," said Poo Mu-ming, scientific director of CEBSIT, and also a CAS academician.

Chinese researchers complete 2nd successful case in invasive brain-computer interface trial in Shanghai

Chinese researchers complete 2nd successful case in invasive brain-computer interface trial in Shanghai

The three astronauts of China's Shenzhou-21 crewed spaceflight mission returned safely to Earth on Friday after completing their planned tasks aboard the Tiangong space station.

The return capsule of the Shenzhou-22 spaceship, carrying Shenzhou-21 astronauts Zhang Lu, Wu Fei and Zhang Hongzhang, touched down at the Dongfeng landing site in north China's Inner Mongolia Autonomous Region at 20:11 Beijing Time (1211 GMT), according to the China Manned Space Agency.

The returned astronauts were reported to be in good physical condition after landing, according to staff on site.

Zhang Lu was the first to exit the return capsule after it touched down on Earth.

"I'm thrilled to once again return to the embrace of our motherland. The Shenzhou-21 crew's seven-month stay in orbit would not have been possible without the care of our families and comrades, the support of leaders at all levels and all colleagues involved in the project, and above all, the backing of our country and our people. One sentence sums up my thoughts on my second space mission: 'It takes a whole team's devotion to make one person's voyage into the sea of stars,' " Zhang said in an interview with China Central Television (CCTV) shortly after he was carried out of the return capsule.

"I also have a gift to share with everyone. On the day of the Shenzhou-21 launch, the ground support team gave us an apple, wishing us a safe and smooth mission. Our safe return is their greatest wish. Tomorrow is May 30, the National Science and Technology Workers' Day. So when we left the space station, we specifically brought back an apple. We want to give it to all science and technology workers, and say 'thank you for your hard work'. At the same time, I wish our space industry continued prosperity, and every mission safe and smooth," he said.

"Returning to Earth and to the embrace of our motherland, I feel extremely secure and proud. Being entrusted with such a significant responsibility in my first space mission is a great honor. It is the trust of my country, the guidance of my predecessors, and the teamwork of the entire crew that enabled me to successfully complete the mission. This mission has taught me that the most beautiful posture of youth is to march out for the country. I will turn this space experience into the driving force for my continued progress, and continue to fight and strive for the manned space program," said crew member Wu Fei.

"From the ground laboratory to China's space station, it is our great motherland that has enabled me to achieve a perfect integration of my scientific ideals and spaceflight dreams. With the support of the entire project team, the assistance of researchers and scientists, and the care of so many people, our crew has worked as one and successfully completed all assigned scientific projects, including the first successful in-orbit breeding of small mammals, the growing of a thriving space vegetable garden with an even wider varieties, and the collection of valuable data from projects such as in-situ electrochemical and optical studies on lithium-ion batteries," said Zhang Hongzhang, who was the last of the astronauts to exit the spacecraft.

"Looking at Earth from space, I deeply felt that humanity is an indivisible community with a shared future. Now that I am back on Earth and have returned to my motherland, I feel an immense sense of security and warmth. Going forward, I will continue to build on these achievements and contribute to making China a strong power in space, science and technology," he said.

The returned crew members will now head to Beijing by plane and enter a quarantined recovery period, during which they will undergo comprehensive medical examinations and health assessments and start their recuperation process.

Prior to their return, the astronauts completed all planned tasks and handed over the space station to their three colleagues of the Shenzhou-23 mission who boarded the space station on May 25.

The crew's planned stay in-orbit was extended by approximately one month to further verify the technologies regarding the long-term stay of astronauts in orbit and fully use the supplies delivered by the Shenzhou-22 spacecraft in an emergency launch.

The Shenzhou-21 crew's original spaceship, which sent them into space on Oct 31 last year, was previously returned to Earth carrying the astronauts of the preceding Shenzhou-20 mission after tiny cracks were found in the viewport window of the Shenzhou-20 manned spacecraft's return capsule. That spacecraft was later safely brought back to Earth.

Shenzhou-21 crew return to Earth after successful seven-month mission in space

Shenzhou-21 crew return to Earth after successful seven-month mission in space

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