Rune Labs Taps Tempus Exec as New CEO to Expand AI-Enabled Neurology Care

SAN FRANCISCO--(BUSINESS WIRE)--Jan 8, 2026--

Rune Labs, the leader in precision medicine for neurology, today announced Amy Gordon Franzen as its new Chief Executive Officer. Amy will lead the company’s next stage of growth, leveraging its success in Parkinson’s Disease, where it has established StrivePD as the industry’s preeminent AI platform and patient app. The company is actively expanding this platform to address additional neurological conditions, including Alzheimer’s disease and other forms of dementia. Co-founder Brian Pepin will become President, Biopharma and Platform, where he will lead Rune Labs’ expanding biopharma partnerships and research portfolio.

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Franzen joins Rune from Tempus, where she played a foundational role in shaping the company’s trajectory from its formative stages into a leading precision-medicine platform used widely across healthcare. As Senior Vice President and General Manager at Tempus, she built and scaled a high-growth clinical trial organization by expanding its data assets and forging new provider and biopharma partnerships that accelerated enrollment across interventional and observational oncology trials. Before joining Tempus, she held leadership roles at Groupon, Nike, and McKinsey & Company, driving growth initiatives and operational improvements across each organization.

“As Rune Labs grows, the work ahead increasingly depends on commercial expansion and deeper alignment with clinicians, payers, and pharma leaders,” said Pepin. “Amy has spent her career building exactly those kinds of partnerships. Bringing Amy on board strengthens the company in ways that will help us reach more patients and providers, while allowing me to continue expanding the biopharma programs that have become a core part of our business.”

Since its launch in 2022, the company’s StrivePD patient engagement platform has evolved into a software ecosystem that supports remote care, AI-enabled symptom tracking and patient reports, and real-world evidence generation for people with Parkinson’s. As the company expands beyond Parkinson’s, it is extending its continuous data and AI infrastructure across the broader aging population - empowering patients with ongoing insight into their condition while working with payers, health systems, and life sciences partners to generate real-world evidence, strengthen trial design and recruitment, and support scalable reimbursement pathways for digitally enabled neurological care.

Franzen’s appointment follows the recent addition of Adam Pellegrini to the Board of Directors, whose background in AI-driven care and reimbursement strategy adds valuable perspective to the team. The appointment of these two seasoned healthcare leaders reflects Rune Labs’ robust foundation and long-term potential to advance the next generation of precision neurology.

“StrivePD has already transformed how people with Parkinson’s understand and manage their disease,” said Franzen. “Our next chapter is about scale – extending the commercial and clinical infrastructure needed to deliver AI-enabled care across all neurology and more deeply integrating with trial sponsors, payers, and health systems.”

About Rune Labs

Rune Labs is a precision medicine company focused on neurology, supporting care delivery and therapy development using the most advanced AI and FDA-cleared algorithms. StrivePD is the company's care delivery ecosystem, which started in Parkinson's disease, empowering patients and their clinicians to take control and better manage their care by providing access to easy to understand insights based on summarized objective and subjective data to improve treatment decisions, enhance disease management and connect patients to clinical trials. For therapeutic development, biopharma and medical device companies leverage Rune's technology, extensive network of engaged clinicians and patients, and large longitudinal real-world datasets to expedite development programs. The company has received financial backing from leading investors such as Nexus NeuroTech, Eclipse Ventures, DigiTx, TruVenturo and Moment Ventures. For more information, please visit runelabs.io and strive.group.

Pictured: Amy Gordon Franzen, new CEO at Rune Labs

WASHINGTON (AP) — President Donald Trump has privately discussed the possibility of firing Attorney General Pam Bondi and replacing her with Environmental Protection Agency Administrator Lee Zeldin, three people familiar with the matter told The Associated Press on Thursday.

In those conversations, Trump has discussed his ongoing frustration with Bondi over her handing of the Jeffrey Epstein files and hurdles the Justice Department has encountered in investigations into Trump’s perceived enemies, the people said. The Republican president has mentioned other candidates but has raised Zeldin’s name as recently as this week, the people said.

The people were not authorized to publicly discuss the private conversations and spoke to the AP on the condition of anonymity.

No decision has been announced, and Trump has been known to change his mind on personnel decisions.

"Attorney General Pam Bondi is a wonderful person and she is doing a good job,” Trump said in a statement produced by the White House.

Zeldin, a former Republican congressman from New York, has been publicly and privately praised by Trump, who at an event in February described him as “our secret weapon.”

Bondi, a former state attorney general in Florida and a Trump loyalist who was part of his legal team during his first impeachment case, has been in her position for more than a year. She came into office pledging that she would not play politics with the Justice Department, but she quickly started investigations of Trump foes, sparking an outcry that the law enforcement agency was being wielded as a tool of revenge to advance the president’s political and personal agenda.

She has also endured months of scrutiny over the Justice Department’s handling of the Epstein files that made her the target of angry conservatives even with her close relationship with Trump.

Under Bondi’s leadership, the department opened investigations into a string of Trump foes, including Federal Reserve Chair Jerome Powell, New York Attorney General Letitia James, former FBI Director James Comey and former CIA Director John Brennan.

The high-profile prosecutions of Comey and James were quickly thrown out by a judge who ruled that the prosecutor who brought the cases was illegally appointed. Other politically charged investigations have either been rejected by grand juries or failed to result in criminal charges.

Attorney General Pam Bondi listens during a Cabinet meeting at the White House, Thursday, March 26, 2026, in Washington. (AP Photo/Alex Brandon)

President Donald Trump walks from the Blue Room to speak about the Iran war from the Cross Hall of the White House on Wednesday, April 1, 2026, in Washington. (AP Photo/Alex Brandon, Pool)