SAN CARLOS, Calif.--(BUSINESS WIRE)--Feb 2, 2026--
Diffuse Bio, a leading provider of AI and experimental platforms for designing and screening protein therapeutics, today announced significant enhancements to DiffuseSandbox, its self-serve protein design platform. DiffuseSandbox now offers large-scale binder design capabilities and direct integration with RamaX, the company's rapid binder screening platform.
This press release features multimedia. View the full release here: https://www.businesswire.com/news/home/20260202041390/en/
The updates create a comprehensive, end-to-end system that enables protein binder discovery in 1-2 weeks—where users can design and then immediately submit large libraries of AI-designed binders such as minibinders, nanobodies, and scFvs for wet lab validation, all within a few clicks.
From Binder Design to Validation in One Step
By directly connecting DiffuseSandbox, its AI design platform, to RamaX experimental screening, Diffuse Bio has created a seamless workflow to design and screen large libraries of protein binders against up to 100 different targets simultaneously—all within 1-2 weeks.
This combination of speed, scale, sensitivity, and selectivity transforms what was once a months-long, resource-intensive, and failure-prone process into a streamlined operation that can be initiated with just a few clicks—enabling researchers to quickly move from initial design concept to validated protein binders in just one step.
Key Platform Enhancements
The expanded DiffuseSandbox now includes two major capabilities:
"RamaX revolutionizes protein therapeutic and reagent design by enabling the rapid discovery of protein binders for up to 100 antigens in parallel, compressing months of work into 1-2 weeks,” notes Namrata Anand, CEO at Diffuse Bio. “This unprecedented speed and scale will accelerate drug programs and will also allow us to generate massive datasets to train better AI protein design models. By rapidly generating large, accurate datasets, we are building the critical foundation required to scale AI performance and unlock the future of generative protein design."
Availability
The platform is available immediately to researchers worldwide via DiffuseSandbox. For partnership on custom data generation or model development, contact the Diffuse Bio team directly at info@diffuse.bio.
About Diffuse Bio
Diffuse Bio builds generative AI and new data platforms for fast and controllable design of proteins. Diffuse’s mission is to design any protein for any purpose, with applications spanning therapeutics, life science tools, diagnostics, and novel enzyme development.
To learn more and stay updated, follow Diffuse Bio on LinkedIn and X or visit https://diffuse.bio.
The end-to-end concept for de novo protein binder design and screening.
NASHVILLE, Tenn. (AP) — Wataru Endo made clear Monday night that Japan has very high expectations for the World Cup.
“We will do our best with pride and passion to achieve something that we’ve never seen before in Japan’s soccer history,” Japan's captain said.
The Liverpool defensive midfielder and his teammates spent nearly an hour at an open practice jogging around the pitch at GEODIS Park, home of Major League Soccer's Nashville club, after arriving earlier Monday. Nashville is home before Japan opens the World Cup on Sunday against the Netherlands in Arlington, Texas, in Group F.
More than 5,000 fans were in the stands watching the open practice. While some traveled from Japan, others came from Michigan, Atlanta and even Austin, Texas, for a glimpse of the Samurai Blue. Japan wrapped up the nearly one-hour session with players taking turns tossing or handing gifts to fans.
Takuro Kaya and his son, Yuhi, wore team gear after driving from North Carolina to support Japan. Kaya said his son's favorite player is Brighton & Hove Albion winger Kaoru Mitoma, who was left off the squad with an injured hamstring, but that his son was excited to see other players like midfielder Junya Ito.
Kaya and his son also will be traveling to the Dallas area to watch Japan play while expecting a deep run in this World Cup.
“We’re so excited and motivated to come here," Kaya said.
Japan is competing at its eighth straight World Cup and aiming to advance beyond the group stage for the third tournament in a row. Japan stunned Germany and Spain for two of the biggest upsets at the last World Cup in Qatar.
The next step is advancing past the round of 16 after being eliminated on penalties by eventual semifinalist Croatia in 2022.
Japan got a taste of Nashville weather, with torrential thunderstorms ahead of its open practice leading to muggy conditions under a hot sun. Goalkeeper Zion Suzuki said he likes Nashville as a host city and doesn't anticipate weather being an issue.
“We practiced in Mexico, and it was really hot," Suzuki said. "So I think of course here U.S. is also hot, but now we are getting ready for that.”
Associated Press writer Kristin M. Hall contributed to this report.
AP World Cup coverage: https://apnews.com/hub/fifa-world-cup
Fans cheer for the Japan national team during a training session Monday, June 8, 2026, in Nashville, Tenn., ahead of the World Cup soccer tournament. (AP Photo/George Walker IV)
Fans cheer for the Japan national team during a training session Monday, June 8, 2026, in Nashville, Tenn., ahead of the World Cup soccer tournament. (AP Photo/George Walker IV)
Shou Itoh, center, cheers for the Japan national team during a training session Monday, June 8, 2026, in Nashville, Tenn., ahead of the World Cup soccer tournament. (AP Photo/George Walker IV)
The Japan national team jogs around the pitch during a training session Monday, June 8, 2026, in Nashville, Tenn., ahead of the World Cup soccer tournament. (AP Photo/George Walker IV)
Japan head coach Hajime Moriyasu takes a picture with fans after a training session Monday, June 8, 2026, in Nashville, Tenn., ahead of the World Cup soccer tournament. (AP Photo/George Walker IV)
