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From 100 to 600 patients: to support patients suffering from acne, Avène, Pierre Fabre Laboratories' leading brand, is strengthening the robustness of its clinical studies via data augmentation through Artificial Intelligence.
TOULOUSE, France, March 11, 2026 /PRNewswire/ -- Avène, the leading brand in French pharmacies*, in partnership with Toulouse-based HealthTech company BotDesign, has announced a major breakthrough in the field of clinical studies in dermo-cosmetics.
In 2026, Avène will conduct a comparative clinical study to evaluate the efficacy of its new treatment for acne-prone skin, Avène Cleanance Comedomed+, in the maintenance phase following oral isotretinoin treatment in adults suffering from severe to very severe acne.
Avène is renowned for its dermatological expertise, inspired by therapeutic know-how, and has been committed to improving the treatment of skin pathologies since 1990. It is thus becoming the first brand to use Artificial Intelligence in clinical studies for dermo-cosmetics.
A concrete illustration of Pierre Fabre Laboratories' "Supportive Care" strategy.
This study is unique in two ways: due to its scientific ambition and because it fully aligns with the "supportive care" strategy of Pierre Fabre Laboratories, launched in 2025.
"We belong to a group that has always been rooted in pharmaceuticals and dermo-cosmetics. Our medical expertise gives us a head start in understanding patients and their pathologies. We are ideally positioned to offer treatment protocols based on the pathology, combining dermo-cosmetics with medication. We are already preparing solutions to go further, by developing dermo-cosmetic innovations capable of extending and amplifying the action of the medication or delaying its necessity. Because these are dermo-cosmetics, they can be used over the long term, unlike many drug treatments," explains Dr. Gautier Doat, Eau Thermale Avène Medical Director.
To continue reading, https://www.pierre-fabre.com/en/news/avene-artificial-intelligence-clinical-studies-dermo-cosmetics
For more information, visit www.pierre-fabre.com, @Laboratoires Pierre Fabre, @Pierre Fabre Oncology
About Eau Thermale Avène: https://www.eau-thermale-avene.fr/
Press contact: Caroline Perdrix Thomas
caroline.perdrix@pierre-fabre.com
*Source: GERS – SOG Early – Pharmacy Channel – Dermo-cosmetics market definition established by Pierre Fabre laboratories – Origin: Sell Out – Cumulative data up to December 2025 in volume (units) and value (revenue inc. taxes).
From 100 to 600 patients: to support patients suffering from acne, Avène, Pierre Fabre Laboratories' leading brand, is strengthening the robustness of its clinical studies via data augmentation through Artificial Intelligence.
TOULOUSE, France, March 11, 2026 /PRNewswire/ -- Avène, the leading brand in French pharmacies*, in partnership with Toulouse-based HealthTech company BotDesign, has announced a major breakthrough in the field of clinical studies in dermo-cosmetics.
In 2026, Avène will conduct a comparative clinical study to evaluate the efficacy of its new treatment for acne-prone skin, Avène Cleanance Comedomed+, in the maintenance phase following oral isotretinoin treatment in adults suffering from severe to very severe acne.
Avène is renowned for its dermatological expertise, inspired by therapeutic know-how, and has been committed to improving the treatment of skin pathologies since 1990. It is thus becoming the first brand to use Artificial Intelligence in clinical studies for dermo-cosmetics.
A concrete illustration of Pierre Fabre Laboratories' "Supportive Care" strategy.
This study is unique in two ways: due to its scientific ambition and because it fully aligns with the "supportive care" strategy of Pierre Fabre Laboratories, launched in 2025.
"We belong to a group that has always been rooted in pharmaceuticals and dermo-cosmetics. Our medical expertise gives us a head start in understanding patients and their pathologies. We are ideally positioned to offer treatment protocols based on the pathology, combining dermo-cosmetics with medication. We are already preparing solutions to go further, by developing dermo-cosmetic innovations capable of extending and amplifying the action of the medication or delaying its necessity. Because these are dermo-cosmetics, they can be used over the long term, unlike many drug treatments," explains Dr. Gautier Doat, Eau Thermale Avène Medical Director.
To continue reading, https://www.pierre-fabre.com/en/news/avene-artificial-intelligence-clinical-studies-dermo-cosmetics
For more information, visit www.pierre-fabre.com, @Laboratoires Pierre Fabre, @Pierre Fabre Oncology
About Eau Thermale Avène: https://www.eau-thermale-avene.fr/
Press contact: Caroline Perdrix Thomas
caroline.perdrix@pierre-fabre.com
*Source: GERS – SOG Early – Pharmacy Channel – Dermo-cosmetics market definition established by Pierre Fabre laboratories – Origin: Sell Out – Cumulative data up to December 2025 in volume (units) and value (revenue inc. taxes).
** This press release is distributed by PR Newswire through automated distribution system, for which the client assumes full responsibility. **
Pierre Fabre Laboratories is exploring the potential of Artificial Intelligence to launch a new generation of clinical studies in dermo-cosmetics
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Performers from the Got Talent universe will headline a new live stage show for families on Legend of the Seas, marking the global format's first-ever show at sea
MIAMI, March 11, 2026 /PRNewswire/ -- Royal Caribbean is making waves with the debut of a brand-new America's Got Talent stage show on Legend of the Seas. In August 2026, America's Got Talent LIVE on Legend of the Seas will deliver a reimagined extension of the beloved global variety show to families from around the world, marking the first time the series will headline at sea.
"At Royal Caribbean, we are constantly redefining live entertainment at every turn—bringing jaw-dropping performances to life across stage, air, water, and ice—and America's Got Talent LIVE on Legend of the Seas is the perfect expression of that vision," said Christine Coachman, vice president of entertainment, Royal Caribbean. "As one of the most acclaimed entertainment franchises on television, America's Got Talent perfectly reflects our commitment to bold, world-class experiences that will truly wow our audiences on Legend."
America's Got Talent LIVE on Legend of the Seas will amplify what has made the Got Talent franchise a global cultural phenomenon. Legend's Royal Theater will showcase a dynamic lineup of unique acts featuring performers from the Got Talent universe, from magicians and musicians to acrobats, aerialists and more.
"We're thrilled to bring Got Talent to an all-new at sea experience as we set sail for the first time with Royal Caribbean," said Erica Gadecki, Executive Vice President of Partnership Solutions, Fremantle. "We can't wait to showcase incredible acts from around the world on a brand-new stage onboard, creating an unforgettable experience for fans."
From iconic performers showcasing the very best of Got Talent from around the globe to the golden ticket debut of Roald Dahl's "Charlie and the Chocolate Factory," Legend will bring to life experiences for all ages with a lineup of top-notch entertainment. Families will be on the edge of their seats with deck-defying high divers, aerialists, robots and dancers in the AquaTheater; and show-stopping performances at Absolute Zero, the largest ice arena at sea. Vacationers can keep the night going at one of more than 20 bars, lounges and live music spots, including jazz tunes at Lou's, sing-offs at Dueling Pianos, and iconic dining experiences transporting guests to the age of cinema at Hollywoodland Supper Club or the Silk Routes at Royal Railway – Legend Station. More information on Legend's new entertainment experiences will be revealed soon.
Legend will level up European summers with 7- night Western Mediterranean vacations from Barcelona, Spain, and Rome (Civitavecchia), Italy, visiting bucket-list locales such as Provence (Marseille), France; Naples, Italy; and Palma De Mallorca, Spain. The Icon Class vacation will then make its grand Caribbean debut in November 2026 with 6-night Western Caribbean and 8-night Southern Caribbean vacations from Fort Lauderdale, Florida. Along with each Caribbean vacation including a visit to Royal Caribbean's top-rated destination at Perfect Day at CocoCay in The Bahamas, adventurers will have the chance to bask in sun-soaked destinations like Oranjestad, Aruba, and Willemstad, Curacao.
For additional information about Legend, vacationers can visit Royal Caribbean's website.
About America's Got Talent
America's Got Talent was created by Simon Cowell and is co-produced by Fremantle and Syco Entertainment. The show has remained the No. 1 summer entertainment broadcast series for 20 consecutive years, with the next season set to premiere on NBC this summer. Simon Cowell, Sam Donnelly and Natasha Brugler are the executive producers. For more information, please visit the official show site at: http://www.nbc.com/agt [nbc.com] and the official press website at https://www.nbcumv.com [nbcumv.com].
About Royal Caribbean
Royal Caribbean, part of Royal Caribbean Group (NYSE: RCL), has delivered memorable vacations for more than 50 years. The cruise line's game-changing ships and exclusive destinations revolutionize vacations with industry-leading innovations and an all-encompassing combination of experiences, from thrills and ways to chill, to dining and entertainment, for every type of family and vacationer. Voted "Best Cruise Line Overall" for 23 consecutive years in the Travel Weekly Readers Choice Awards, Royal Caribbean makes memories with adventurers across more than 300 destinations in 80 countries on all seven continents, including the vacation brand's Perfect Day at CocoCay and Royal Beach Club Paradise Island in The Bahamas, plus four new signature destinations joining the growing lineup by 2027.
Media can stay up to date by following @RoyalCaribPR on X and visit www.RoyalCaribbeanPressCenter.com. For additional information or to book, vacationers can visit www.RoyalCaribbean.com, call (800) ROYAL-CARIBBEAN or contact their travel advisor.
Video - https://www.youtube.com/watch?v=BPVaTkD8YoI
Performers from the Got Talent universe will headline a new live stage show for families on Legend of the Seas, marking the global format's first-ever show at sea
MIAMI, March 11, 2026 /PRNewswire/ -- Royal Caribbean is making waves with the debut of a brand-new America's Got Talent stage show on Legend of the Seas. In August 2026, America's Got Talent LIVE on Legend of the Seas will deliver a reimagined extension of the beloved global variety show to families from around the world, marking the first time the series will headline at sea.
"At Royal Caribbean, we are constantly redefining live entertainment at every turn—bringing jaw-dropping performances to life across stage, air, water, and ice—and America's Got Talent LIVE on Legend of the Seas is the perfect expression of that vision," said Christine Coachman, vice president of entertainment, Royal Caribbean. "As one of the most acclaimed entertainment franchises on television, America's Got Talent perfectly reflects our commitment to bold, world-class experiences that will truly wow our audiences on Legend."
America's Got Talent LIVE on Legend of the Seas will amplify what has made the Got Talent franchise a global cultural phenomenon. Legend's Royal Theater will showcase a dynamic lineup of unique acts featuring performers from the Got Talent universe, from magicians and musicians to acrobats, aerialists and more.
"We're thrilled to bring Got Talent to an all-new at sea experience as we set sail for the first time with Royal Caribbean," said Erica Gadecki, Executive Vice President of Partnership Solutions, Fremantle. "We can't wait to showcase incredible acts from around the world on a brand-new stage onboard, creating an unforgettable experience for fans."
From iconic performers showcasing the very best of Got Talent from around the globe to the golden ticket debut of Roald Dahl's "Charlie and the Chocolate Factory," Legend will bring to life experiences for all ages with a lineup of top-notch entertainment. Families will be on the edge of their seats with deck-defying high divers, aerialists, robots and dancers in the AquaTheater; and show-stopping performances at Absolute Zero, the largest ice arena at sea. Vacationers can keep the night going at one of more than 20 bars, lounges and live music spots, including jazz tunes at Lou's, sing-offs at Dueling Pianos, and iconic dining experiences transporting guests to the age of cinema at Hollywoodland Supper Club or the Silk Routes at Royal Railway – Legend Station. More information on Legend's new entertainment experiences will be revealed soon.
Legend will level up European summers with 7- night Western Mediterranean vacations from Barcelona, Spain, and Rome (Civitavecchia), Italy, visiting bucket-list locales such as Provence (Marseille), France; Naples, Italy; and Palma De Mallorca, Spain. The Icon Class vacation will then make its grand Caribbean debut in November 2026 with 6-night Western Caribbean and 8-night Southern Caribbean vacations from Fort Lauderdale, Florida. Along with each Caribbean vacation including a visit to Royal Caribbean's top-rated destination at Perfect Day at CocoCay in The Bahamas, adventurers will have the chance to bask in sun-soaked destinations like Oranjestad, Aruba, and Willemstad, Curacao.
For additional information about Legend, vacationers can visit Royal Caribbean's website.
About America's Got Talent
America's Got Talent was created by Simon Cowell and is co-produced by Fremantle and Syco Entertainment. The show has remained the No. 1 summer entertainment broadcast series for 20 consecutive years, with the next season set to premiere on NBC this summer. Simon Cowell, Sam Donnelly and Natasha Brugler are the executive producers. For more information, please visit the official show site at: http://www.nbc.com/agt [nbc.com] and the official press website at https://www.nbcumv.com [nbcumv.com].
About Royal Caribbean
Royal Caribbean, part of Royal Caribbean Group (NYSE: RCL), has delivered memorable vacations for more than 50 years. The cruise line's game-changing ships and exclusive destinations revolutionize vacations with industry-leading innovations and an all-encompassing combination of experiences, from thrills and ways to chill, to dining and entertainment, for every type of family and vacationer. Voted "Best Cruise Line Overall" for 23 consecutive years in the Travel Weekly Readers Choice Awards, Royal Caribbean makes memories with adventurers across more than 300 destinations in 80 countries on all seven continents, including the vacation brand's Perfect Day at CocoCay and Royal Beach Club Paradise Island in The Bahamas, plus four new signature destinations joining the growing lineup by 2027.
Media can stay up to date by following @RoyalCaribPR on X and visit www.RoyalCaribbeanPressCenter.com. For additional information or to book, vacationers can visit www.RoyalCaribbean.com, call (800) ROYAL-CARIBBEAN or contact their travel advisor.
Video - https://www.youtube.com/watch?v=BPVaTkD8YoI
** This press release is distributed by PR Newswire through automated distribution system, for which the client assumes full responsibility. **
ROYAL CARIBBEAN'S NEWEST VACATION WILL BRING AMERICA'S GOT TALENT TO SEA FOR THE FIRST TIME
