MILAN--(BUSINESS WIRE)--Jun 17, 2026--
WISE S.p.A., a pioneering medical device company specializing in advanced implantable electrodes for neuromonitoring, neuromodulation, and brain-computer interface (BCI), today announced the successful closing of an oversubscribed Series D financing round totaling €30 million. The round was joined by ENEA Tech and Biomedical, an Italian foundation dedicated to innovation and technology transfer in the biomedical sector, which enters WISE's investor base as a strategic partner. This final closing builds on the first closing of the round completed in June 2024, which included a venture debt facility from the European Investment Bank (EIB) supported by InvestEU, alongside an equity investment from new investor Wallaby S.p.A. — the family office of the Scagliarini family (GVS S.p.A.) — and existing financial partners New Frontier S.r.l., Eureka Venture SGR, and Indaco Ventures SGR.
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Accelerating the Heron® Lead to Clinical Adoption
The primary use of the proceeds is to advance the development and clinical adoption of the Heron® lead, WISE's flagship product for spinal cord stimulation (SCS). The Heron® lead is the first SCS lead designed to deliver targeted, directional stimulation through a minimally invasive percutaneous implant technique — uniquely combining the therapeutic precision of surgical paddle leads with the lower procedural burden of cylindrical leads. This dual advantage translates into higher energy efficiency, better anatomical coverage, improved neural signal sensing, and reduced lead migration, representing a significant step forward in the treatment of chronic pain.
Proceeds will fund the Heron® lead’s regulatory certification pathway and first-in-human study, while also driving the commercial scale-up of WISE's full electrode portfolio across target markets.
A Differentiated Platform for Next-Generation Neurotechnology
WISE's proprietary Supersonic Technology enables the production of implantable electrodes and BCI systems consisting of stretchable electronic circuits integrated into ultra-thin elastomeric foils. Compared to conventional rigid electrodes, WISE's devices deliver superior tissue conformability, softness, and adhesion — qualities that are critical to both safety and therapeutic efficacy in neuromonitoring and neurostimulation applications. These unique characteristics of WISE's technology also enable enhanced precision in neural signal acquisition and stimulation, positioning WISE at the forefront of next-generation neural interfacing.
Alongside the Heron® lead, the round will support expanded commercialization of the WISE Cortical Strip (WCS®), the first soft, stretchable electrode for intraoperative neurophysiological monitoring (IONM) during brain tumor and epilepsy surgeries. The WCS® holds CE mark under MDR — the first cortical strip for IONM to achieve this certification — as well as FDA clearance and is commercially available in Europe, USA, and Australia.
Strengthening WISE's Governance
The round's closing also brings the appointment of Laura Iris Ferro as Chairperson of the company and the addition of Giuseppe Corvino to the Board of Directors. Laura Iris Ferro is one of the most prominent leaders in Italian and European biotech: founder of Gentium, a Nasdaq-listed company acquired in 2014 by Jazz Pharmaceuticals in a transaction worth approximately USD 1 billion, she is today President and co-founder of Bio4Dreams and holds leadership and investment roles across numerous innovative companies in the Life Sciences sector.
“The oversubscription of this Series D round is a testament to the strength of what our team has built — in technology, in medical research, and in our relationships with clinicians and partners,” said Luca Ravagnan, Chief Executive Officer of WISE. “Welcoming ENEA Tech and Biomedical into our investor base strengthens our mission to bring genuinely transformative neurotechnology to patients worldwide. With the Heron® lead, we are targeting a multi-billion-euro market with a product that addresses a long-lasting unmet clinical need. This financing gives us the resources to complete the journey from bench to bedside.”
“WISE represents a compelling convergence of advanced materials science, neuroscience, and clinical innovation,” commented Laura Iris Ferro, Chairperson of WISE. “Welcoming ENEA Tech and Biomedical on board is a testament to the strength of what WISE has built. I am proud to help the company scale its technology and bring high-impact solutions to patients with neurological conditions and chronic pain.”
About Wise Spa and Enea Tech and Biomedical
WCS: wise cortical strip
DUBAI, United Arab Emirates (AP) — U.S. President Donald Trump has warned Iran that the U.S. will destroy one bridge or power plant each time Iran shoots at a ship in the Strait of Hormuz.
In his warning on social media, the president returned to earlier threats to target civilian infrastructure in retaliation for Iranian attacks. It comes as strikes have escalated on both sides, leaving an interim deal to end the war in tatters.
“From this point forward, any time the Islamic Republic of Iran shoots at a ship in the Strait of Hormuz, whether it be by Missile, Rocket, Drone, or any other device or weapon, the United States will bomb and destroy ONE BRIDGE OR POWER PLANT,” Trump wrote on social media.
THIS IS A BREAKING NEWS UPDATE. AP’s earlier story follows below.
DUBAI, United Arab Emirates (AP) — The United States on Wednesday carried out another wave of strikes on Iran, where air defenses opened fire over the capital, Tehran. Iran launched a missile attack on a Jordanian city on Israel’s doorstep, and alerts were issued in Bahrain and Saudi Arabia.
The 11th night of American airstrikes on Iran came as diplomatic efforts have shown little public sign of progress. Officials on both sides have dug in on their dispute over the Strait of Hormuz, a crucial waterway for global energy that remains largely closed because of Iranian attacks.
Iran has avoided striking Israel since hostilities resumed last month, apparently hoping to keep it from reentering the war. But the missile and drone attack on Jordan’s city of Aqaba, within sight of Israel’s Eilat, raised concerns over a further widening of the conflict after an agreement to halt hostilities collapsed.
The closure of the strait, through which a fifth of the world’s traded oil and gas passed during peacetime, has jolted the world economy with effects far beyond the Middle East. A new threat by Iran-backed Houthi rebels in Yemen to target Saudi shipping in the Red Sea puts another trade chokepoint at risk.
Benchmark Brent crude oil rose to around $94 a barrel in trading, and gasoline prices are once again climbing ahead of U.S. midterm elections this fall.
Jordan’s military said it intercepted four Iranian missiles over Aqaba, while two others fell in “uninhabited areas.” Plumes of smoke could be seen overhead in videos filmed by people in the nearby Israeli city of Eilat. Jordan said it also intercepted four Iranian drones.
Another missile alert sounded in Bahrain, and Saudi Arabia warned residents of the Persian Gulf city of Dammam to seek shelter. Saudi authorities later said the danger had passed, without elaborating.
The U.S. military said earlier Wednesday that it had completed an 11th night of strikes on Iran, with targets including aircraft hangars and drone storage sites.
Iran's state-run IRNA news agency reported explosions across several provinces. Iran's Health Ministry says U.S. strikes over the past 11 days have killed 53 people, including six women and three children, and wounded nearly 600 people.
Iran's paramilitary Revolutionary Guard insisted its retaliatory attacks would continue.
Before the latest strikes, Iranian Interior Minister Eskandar Momeni visited Pakistan, a key mediator in the conflict, seeking to revive diplomacy. But it was unclear what new arrangement might be reached to end the war, which lately has become a battle for control over the Strait of Hormuz.
Iran's Interior Ministry spokesman Ali Zeinivand said “diplomacy isn’t called off” and that messages were still being exchanged, without elaborating, according to IRNA.
At a regional summit in the Philippines, U.S. Secretary of State Marco Rubio denounced Iran’s actions in the strait.
“If we create a precedent in the Middle East where a nation state can decide that they are going to control an international waterway, charge a toll and if you don’t pay them, blow up your ships, we have created a very dangerous precedent which will repeat itself in other parts of the world, including in this region,” he said.
In response to Iran’s attacks, the U.S. re-imposed a blockade on Iranian ports.
Speaking from the Oval Office on Tuesday, U.S. President Donald Trump gave a dim view on possible talks, saying the U.S. had “no interest in meeting.”
He signaled that U.S. forces could soon target an under-construction Iranian nuclear site buried deep under a mountain.
The site, known as Pickaxe Mountain, lies on the south side of Iran’s Natanz nuclear enrichment site, which was bombed by the U.S. during the 12-day war between Iran and Israel in 2025. But Pickaxe Mountain has remained untouched as Iran continues to dig at the site.
Iran has always insisted its nuclear program is peaceful, while resuming the enrichment of uranium to near weapons-grade levels since Trump scrapped a 2015 nuclear deal during his first term. The U.S. and others believe Iran had a nuclear weapons program until 2003 and may reconstitute it in the future.
Binkley reported from Washington. Associated Press writers Bassem Mroue in Beirut, and Michelle L. Price and Jim Gomez in Manila, Philippines, contributed to this report.
Secretary of State Marco Rubio speaks during a press conference on the sidelines of the Association of Southeast Asian Nations (ASEAN) Foreign Ministers' Meeting in Pasay, Metro Manila, Philippines Wednesday, July 22, 2026. (Brendan Smialowski/Pool Photo via AP)
