LAS VEGAS--(BUSINESS WIRE)--Aug 4, 2026--
Massive Bio, Inc., a global precision oncology and AI-enabled real-world data company, today announced at Ai4 2026 that it has made a strategic investment in Rivvi AI, Inc., an agentic AI infrastructure company for healthcare and life sciences. The transaction is Massive Bio’s first strategic investment in another AI company. It builds on the companies’ existing work across oncology trial programs and pairs capital with a shared plan to connect clinical intelligence, personalized patient outreach, and human-led navigation. Financial terms were not disclosed.
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The investment marks a deliberate expansion of Massive Bio’s strategy: building core AI products while selectively deploying capital into complementary technologies that increase the reach and value of its platform. The companies intend to align technology and go-to-market capabilities across oncology clinical trials, patient support, care-gap closure, medication adherence, and other complex-care workflows.
“Massive Bio has reached a point where we can create value by building, partnering, and investing. Rivvi is our inaugural AI investment because its conversational infrastructure compounds the value of our clinical intelligence. We identify the right opportunity; Rivvi helps make the right conversation possible; our clinical and navigation network carries that conversation toward an informed action. This is disciplined capital deployment around a shared mission, and it establishes a model for how we can accelerate the most important technologies surrounding our platform,” saidSelin Kurnaz, PhD, Co-Founder and Chief Executive Officer of Massive Bio.
Closing the Gap Between Intelligence and Action
An estimated 3% to 5% of adults with cancer in the United States enroll in therapeutic clinical trials. The persistent gap is driven in part by fragmented data, increasingly complex eligibility criteria, limited workforce capacity, and missed opportunities to reach patients during a narrow clinical window. Massive Bio addresses the intelligence layer by structuring clinical and biomarker data, identifying relevant trials, and supporting navigation. Rivvi adds the action layer: AI agents that turn each match into a governed, auditable workflow, reaching patients, surfacing barriers, coordinating next steps, and escalating to the appropriate human team.
Massive Bio’s neuro-symbolic, multi-agent matching system was evaluated prospectively in 3,804 patients during routine oncology operations. The peer-reviewed study reported more than 17,000 oncologist-confirmed matches, an F1 score of 0.82, and trial matching four times faster than conventional workflows. Rivvi has powered more than two million patient interactions across more than 500,000 patients and serves health systems, payers, pharmacies, PBMs, and life sciences organizations.
“An eligible patient cannot benefit from an opportunity they never hear about, and in oncology the window can close quickly. Connecting prospectively validated matching with consent-aware conversations and human navigation is a clinically meaningful step. Clinical judgment stays with clinicians and choice stays with patients; AI creates the capacity to bring more people into an informed discussion with the right care team at the right time,” saidArturo Loaiza-Bonilla, MD, MSEd, FACP, Co-Founder and Chief Medical AI Officer of Massive Bio.
A Three-Layer Patient-Action Architecture
The companies’ integration roadmap is designed around three connected layers:
The design preserves clear boundaries. Rivvi’s AI does not diagnose, prescribe, or override clinical judgment. Each organization can configure policies, escalation rules, access controls, and audit trails for its workflows. Rivvi’s platform is HIPAA compliant and SOC 2 Type II, with business associate agreements available, and supports deployment without requiring a new electronic medical record integration.
“The value of healthcare AI is realized when a signal becomes a completed, traceable workflow. Our roadmap connects neuro-symbolic reasoning and knowledge-graph intelligence with Rivvi’s policy-governed conversational infrastructure. Each transition can be authorized, logged, and escalated. That modular, interoperable, human-governed architecture is how enterprise AI moves from demonstrations into reliable operations,” saidÇağatay M. Çulcuoğlu, Co-Founder, Chief Technology Officer and Chief Operating Officer of Massive Bio.
Designed to Compound Value Across the Healthcare Ecosystem
The transaction establishes a repeatable model for Massive Bio to evaluate and selectively invest in AI companies that strengthen the patient journey. Massive Bio brings clinical evidence standards, oncology domain expertise, pharmaceutical and health-system relationships, and experience deploying across 17 countries. Rivvi contributes specialized infrastructure for personalized healthcare conversations, workflow governance, and rapid operational scale.
“Massive Bio brings the oncology intelligence, evidence base, global reach, and operational network to identify where action matters most. Rivvi brings the infrastructure to conduct and govern personalized patient conversations at scale. Their investment accelerates our ability to serve life sciences and complex-care programs, and together we can help healthcare organizations reach more patients with the context, timing, and human support needed to act,” saidNathan Hayman, Co-Founder and Chief Executive Officer of Rivvi.
About Massive Bio
Massive Bio, co-founded by Selin Kurnaz, Arturo Loaiza-Bonilla, and Çağatay Çulcuoğlu, transforms the pharmaceutical value chain with AI-driven solutions. As an AI-enabled real-world data company, Massive Bio streamlines patient journeys, improves access to cutting-edge treatments, and optimizes clinical trial operations across 17 countries. A recipient of the DiMe Seal, the Digital Medicine Society’s independent quality certification covering clinical evidence, privacy, security, and usability, Massive Bio is listed in the CMS Medicare App Library, connecting its platform to more than 68 million Medicare beneficiaries. A founding member of the CancerX public-private partnership and participant in the White House Cancer Moonshot initiative, the company continues to lead the way in ethical AI and data-driven innovation.
For more information, visit www.massivebio.com.
About Rivvi
Rivvi is the agentic AI infrastructure that turns healthcare and life sciences intelligence into completed, governed action. Its orchestrator agents learn each organization, compose programs, and run them end-to-end across care-gap closure, medication adherence, chronic-care management, population health, and life sciences programs. Rivvi has powered more than two million patient interactions across more than 500,000 patients. The platform combines agentic AI, data intelligence, HIPAA and SOC 2 Type II governance, auditability, and human escalation to extend the capacity of healthcare teams.
Learn more at rivvi.ai.
Massive Bio announces its inaugural strategic investment in Rivvi to build end-to-end AI engagement infrastructure for healthcare.
SPOKANE, Wash. (AP) — A man who went to prison for manslaughter in his father’s 2010 killing in Arizona has been charged with setting the largest of the wildfires that have destroyed hundreds of buildings in and around Washington state’s second-largest city and forced tens of thousands of people from their homes.
Aaron F. Farinacci, of Spokane, was arrested Monday and booked on suspicion of first-degree arson in connection with the Old Trails Fire, the biggest of the three blazes in and around the eastern Washington city, the Spokane County Sheriff’s Office said. His bond was set at $1 million.
The fires, which hadn't been contained at all as of Tuesday morning, have destroyed at least 700 buildings and forced about 67,000 people to evacuate. Authorities haven’t said what might have caused the other two blazes.
A tip from a community member who saw a nervous-looking man bent by the side of the road near some grass led authorities to Farinacci, though they released him after initial questioning, Sheriff John Nowels said Monday.
When major crimes detectives started investigating, they again identified Farinacci and determined that the fire had started where the witness had reportedly seen him, Nowels said. Farinacci had matches and a lighter when he was detained, Nowels said.
“As it happens in so many critical cases, it was citizens who were paying attention to their surroundings, being aware and willing to step up and say something that led to the relatively quick apprehension of Mr. Farinacci,” he said.
Farinacci, 37, was set to appear in court Tuesday, according to Spokane County Prosecutor Preston McCollam. A phone number couldn't be found for Farinacci and it wasn't immediately clear if he had an attorney who could speak on his behalf. An email was sent to the Spokane County Public Defender's office on Tuesday and a message was sent to a possible social media account for a brother.
In Mesa, Arizona, in 2010, Farinacci, then age 21, shot and killed his father during an argument about washing dishes, police said at the time. Farinacci also shot himself but survived.
He was charged with murder but pleaded guilty in 2012 to manslaughter and aggravated assault, records show. Farinacci was released from prison in 2020.
The Old Trails Fire began Saturday northwest of downtown Spokane and eventually jumped the Spokane River and tore through neighborhoods.
The three fires had burned about 16 square miles (about 41 square kilometers) by early Tuesday. After the weekend winds died down and shifted, sending smoke across the western part of the state, including the Seattle area, firefighting conditions were expected to worsen again Wednesday, with winds picking up and temperatures expected to reach the 90s (32-37 degrees Celsius), said Benjamin Cossel, a spokesperson for the fire incident management team.
On Monday, some residents who had to flee blazes over the weekend returned to find homes that had been burned to the ground. In some cases, only chimneys were left standing.
“There’s nothing to save,” Miriam Sim, 76, said as she and her husband, Daniel Sim, surveyed the ruins of the home where they had lived since 2005.
“At our age, do we want to rebuild?” her husband asked.
In one Spokane neighborhood, blackened vehicles, a boat twisted by the heat and melted plastic recycling bins remained. Across the street, lawns were still green and houses were spared, as residents continued to run hoses or sprinklers to water their properties.
“Hundreds of people have completely lost their homes and farms, and many are prohibited from returning to their homes or neighborhoods as crews continue to extinguish smoldering embers,” the state's congressional delegation wrote Monday in asking President Donald Trump to approve an expedited emergency declaration, which he did.
Cpl. Mark Gregory, a spokesperson for the Spokane County Sheriff’s Office, said the county initially received nearly 300 reports of missing people, but by Monday had cleared all but 14. Those still unaccounted for were likely people who hadn't been in contact since evacuating, not people who were truly missing or in danger, authorities said.
More than 1,000 firefighters, many from out of state, arrived by Monday, and that number was expected to double in the next few days.
The fires were among dozens across the Western U.S. stretching the ability of federal, state and local agencies to fight them. At least 390 square miles (1,000 square kilometers) of land has burned across Washington, which has been dealing with a severe drought and paltry snowpack.
Authorities warned people not to fly drones near the burned areas, saying it could force them to delay aerial firefighting operations.
Angela and Wayde Deatherage, both 49, evacuated shortly after 3 p.m. Saturday with a son, grabbing a few bins of family photos and heirloom rings but not much else. Roughly 30 minutes later, their security camera was sending fire notifications to Angela’s phone.
Wayde Deatherage took some back roads and returned by early evening. He stopped at the end of the street and called his wife: “Our house is done.”
Deatherage, however, wasn't done with his neighborhood. He propped a hose at another house so it sprayed the property. That home survived.
The couple returned to their property Sunday.
“It’s just ash,” Angela Deatherage said of the home where they had lived for nearly 22 years. “It’s like our house sunk down in the basement. ... There’s just so much loss for so many people.”
Karen Faggioli, 61, figured she would be returning to her home. She recalled how other recent fires had been brought under control. But a relative texted her the bad news: Her house and three vehicles had been destroyed. A daughter lost her nearby house, too.
“Why cry? What’s crying going to do? I’ve been through so many tragedies myself,” said Faggioli, who is recovering from breast cancer. “This is nothing. Like I told my granddaughter, ‘We’re strong — and now we get all new things.’ I’m emotionally numb.”
Johnson reported from Seattle and White from Detroit. Associated Press writers Manuel Valdes in Spokane; John Hanna in Topeka, Kansas; Kathy McCormack in Concord, New Hampshire; and Martha Bellisle and Hallie Golden in Seattle contributed.
Allen Sather stands in front of his 1968 Chevrolet C20 at the duplex he rented on W. Indian Trail Rd. that burned in a wildfire in Spokane, Wash., Sunday, Aug. 2, 2026. (AP Photo/Young Kwak)
From left, homeowner Al Acosta, his son Louis Acosta, daughter Renee Stewart and son-in-law Jamie Stewart look through the remains of Al's home after a wildfire hit the northern part of Spokane, Wash., Monday, Aug. 3, 2026. (AP Photo/Lindsey Wasson)
A "for sale" sign is still seen on the back of a van burned after a wildfire hit the northern part of Spokane, Wash., Monday, Aug. 3, 2026. (AP Photo/Lindsey Wasson)
Chimneys are the only structures remaining in a residential neighborhood after a wildfire hit the northern part of Spokane, Wash., Monday, Aug. 3, 2026. (AP Photo/Lindsey Wasson)
Trees burned by a wildfire stand near destroyed structures in the Indian trail neighborhood, Monday, Aug. 3, 2026, in Spokane, Wash. (AP Photo/Young Kwak)
Miriam Sim, 76, reacts as she walks through the burned remains of her neighborhood after a wildfire hit the northern part of Spokane, Wash., Monday, Aug. 3, 2026. (AP Photo/Lindsey Wasson)
Daniel Sim, 76, views the remains of his destroyed house after a wildfire hit the northern part of Spokane, Wash., Monday, Aug. 3, 2026. (AP Photo/Lindsey Wasson)
Miriam Sim, 76, reacts while talking about her neighborhood largely burning to the ground after a wildfire hit the northern part of Spokane, Wash., Monday, Aug. 3, 2026. (AP Photo/Lindsey Wasson)
A worker with Avista moves through a property after a wildfire hit the northern part of Spokane, Wash., Monday, Aug. 3, 2026. (AP Photo/Lindsey Wasson)
