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NTx Announces Full Commercial Availability of NTxscribe to Broadly Enable RNA Therapies

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NTx Announces Full Commercial Availability of NTxscribe to Broadly Enable RNA Therapies
News

News

NTx Announces Full Commercial Availability of NTxscribe to Broadly Enable RNA Therapies

2025-01-09 22:01 Last Updated At:22:12

RIO RANCHO, N.M.--(BUSINESS WIRE)--Jan 9, 2025--

Nature’s Toolbox (NTx), a life sciences company developing next-generation platforms for RNA and protein manufacturing, today announced the full commercial availability of NTxscribe ®, a benchtop, continuous flow RNA in vitro transcription (IVT) and purification system that brings cost effective and scalable RNA manufacturing to the market.

This press release features multimedia. View the full release here: https://www.businesswire.com/news/home/20250109963944/en/

Traditional RNA production methods are costly and complex. This slows clinical innovation, makes it hard to scale production to meet demand, and makes it nearly impossible to produce affordable personalized medicines. NTxscribe solves these challenges with a benchtop system that produces high-yield, high-integrity RNA in continuous flow and can scale seamlessly from small research doses to commercial volumes. NTxscribe produces 10-50 mg of high integrity RNA in two hours, shortening timelines for bringing new therapies and vaccines to market and empowering researchers, biotech, and pharmaceutical companies to make personalized medicine a reality.

“Our team has worked closely with NTx and utilized the innovative NTxscribe system for the last several years,” said John Cooke, MD, Ph.D., Medical Director of the RNA Therapeutics Program at the Houston Methodist DeBakey Heart and Vascular Center. “Through our partnership on a contract from Biomedical Advanced Research and Development Authority (BARDA), we were able to deliver exceptional results in demonstrating how NTxscribe can fulfill the need for a rapidly deployable RNA vaccine manufacturing capability. After seeing the final commercial product at NTx’s recent Scientific Advisory Board session, I believe we are seeing the future of how medicine will be delivered.”

NTxscribe’s small footprint enables rapid deployment even in mobile cleanrooms. Lower infrastructure costs make high-quality RNA production accessible to a wider range of organizations, including smaller labs and startups. NTxscribe also utilizes 100% U.S. made raw materials and enables an end-to-end domestic supply chain for critical biomaterials, in contrast to the current reality of profound dependence on China.

“Traditional biomanufacturing methods have not been able to keep pace with the surge in therapeutic innovation and rise of personalized medicine, and until now, there has not been a solution for the gaps in scalability and quality,” said Jamie Coffin, President and CEO at NTx. “Following our fully subscribed early access program with leading academic medical centers and major biopharma organizations, we are excited to bring NTxscribe to the broader market and help unlock the full potential of RNA therapies by enabling innovation for the future of medicine.”

To learn more about NTxscribe and how NTx can help address different biomanufacturing needs, please schedule a design session here: https://ntxbio.com/reserve.

About NTx

Nature’s Toolbox, Inc. (NTx), based in Rio Rancho, New Mexico, is revolutionizing biomanufacturing with cutting-edge solutions tailored to the demands of modern research and personalized medicine. NTx is developing innovative systems like NTxscribe® and NTxpress® to enable the sustainable production of mRNA and protein therapeutics, offering scalability from personalized doses to mass-market volumes. Discover how NTx is shaping the future of medicine at www.ntxbio.com.

NTx announced the full commercial availability of NTxscribe®, a benchtop, continuous flow RNA in vitro transcription (IVT) and purification system that brings cost effective and scalable RNA manufacturing to the market. (Photo: Business Wire)

NTx announced the full commercial availability of NTxscribe®, a benchtop, continuous flow RNA in vitro transcription (IVT) and purification system that brings cost effective and scalable RNA manufacturing to the market. (Photo: Business Wire)

Israel struck Iran on Monday after being targeted by missiles, while a U. S. military base in Saudi Arabia came under fire in the most serious exchange of hostilities since an April ceasefire, raising the possibility of a return to heavy fighting and complicating mediation efforts to end the war.

Iranian state television reported the sound of explosions being heard in Isfahan, Tabriz and Tehran, without immediately elaborating. Earlier, Iran had launched missiles at Israel in the first such bombardment since a fragile ceasefire took effect in early April, raising the possibility of a return to heavy fighting and complicating mediation efforts to end the war.

Tehran had warned of retaliation after Israel struck Beirut’s southern suburbs without warning earlier Sunday in defiance of Washington’s request days ago to stand down. Israel said the Iranian-backed Hezbollah fired at northern Israel earlier in the day.

Saudi Arabia sounded missile alert sirens Monday morning in an area home to an air base that hosts U.S. forces.

The Israeli strikes came in apparent defiance to President Donald Trump who urged Israeli Prime Minister Benjamin Netanyahu that he doesn’t think Israel needs to respond further.

Speaking to The Financial Times, U.S. President Donald Trump before the Israeli strike on Iran insisted he dictated terms to Israeli Prime Minister Benjamin Netanyahu on how the war should be prosecuted.

“He won’t have any choice,” Trump told the newspaper in a telephone interview. “I call the shots. I call all the shots. He (Netanyahu) doesn’t call the shots.”

Here's the Latest:

Israel said Monday that it detected a missile launched from Yemen targeting the country. Sirens sounded across Israel after the Yemen missile fire warning.

Yemen is home to the Iranian-backed Houthi rebels. The Houthis have fired missiles at Israel during the Israel-Hamas war and later, but haven’t been fully involved in the Iran war.

Saudi Arabia sounded missile alert sirens Monday morning in an area home to an air base that hosts U.S. forces. Saudi state media reported the alert around its Al Kharj governorate, home to Prince Sultan Air Base.

It did not elaborate. The alert came after Israel launched strikes targeting Iran.

Speaking to The Financial Times, U.S. President Donald Trump before the Israeli strike on Iran insisted he dictated terms to Israeli Prime Minister Benjamin Netanyahu on how the war should be prosecuted.

“He won’t have any choice,” Trump told the newspaper in a telephone interview. “I call the shots. I call all the shots. He (Netanyahu) doesn’t call the shots.”

The White House did not respond to messages Sunday about the strikes and whether they were done in coordination with the U.S.

Iran closes airspace around Tehran’s Imam Khomeini International Airport, country’s main airfield, after Israeli attack.

Israel says it strikes central and Western Iran after missile fire; Tehran says explosions heard in several cities

A projectile streaks through the sky over central Israel during an Iranian missile attack, Sunday, June 7, 2026. (AP Photo/Ohad Zwigenberg)

A projectile streaks through the sky over central Israel during an Iranian missile attack, Sunday, June 7, 2026. (AP Photo/Ohad Zwigenberg)

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