EAST BRUNSWICK, N.J.--(BUSINESS WIRE)--Jul 21, 2025--
Cronus Pharma LLC, a fully integrated research, development, manufacturing, sales and marketing animal health pharmaceutical company, announces the launch of Butorphic® (Butorphanol Tartrate) Sterile Injectable Solution for immediate availability in the U.S. animal health market through national and regional distributors.
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"Butorphic is a vital analgesic for managing equine colic pain and we are excited to grow our equine portfolio. Importantly, Butorphic marks our fifth product launch this year, expanding our portfolio to twenty-five products with several more planned for 2025 and beyond," said Vimal Kavuru, Chairman & CEO.
This launch enhances Cronus Pharma's robust sedative and anesthesia product portfolio which includes AnaSed® Equine (Xylazine) Injection, Cropamezole™ (Atipamezole) Injection, DexmedVet™ (Dexmedetomidine) Injection, DetomiSed™ (Detomidine) Injection, and Ketamine Injection.
"Butorphic's launch reinforces our position among the animal health leaders in U.S. FDA ANADA approvals over the past several years, which is a testament to our team’s dedication to delivering high-quality, cost-effective pharmaceuticals to veterinarians and pet owners," said Edward Neugeboren, Chief Strategy Officer.
Butorphic is indicated for the relief of pain associated with colic and postpartum pain in adult horses and yearlings. Clinical studies demonstrate that butorphanol tartrate effectively alleviates abdominal pain caused by torsion, impaction, intussusception, spasmodic and tympanic colic, and postpartum pain. Approved by the FDA under ANADA #200-332, Butorphic provides the same efficacy and safety, and is a generic equivalent to the reference product, Torbugesic®. Available in 10 mg/mL concentrations in 20 mL and 50 mL multi-dose vials, our unique 20 mL vial offers veterinarians more flexible dosing options.
Please refer to the Package Insert for complete prescribing instructions, precautions, and full safety information.
About Cronus Pharma
Cronus is a fully integrated research, development, manufacturing, sales and marketing animal health pharmaceutical company headquartered in East Brunswick, New Jersey, dedicated to providing high-quality and cost-effective pharmaceuticals serving the companion, equine and production animal health markets. Through our in-house R&D and acquisitions, Cronus has an extensive product portfolio of seventy-seven US FDA approved products as well as numerous products pending approval and a broad development pipeline. Cronus is proud to be among the leaders in U.S FDA ANADA approvals in the animal health industry over the past several years. Our recently built state of the art manufacturing facility located in Hyderabad, India has broad capabilities including solid oral dose, sterile injectables and cephalosporins. Our products are available to veterinarians and pet owners nationwide through national and regional distributors. Our passionate team is committed to growing our business and being among the leading animal health pharmaceutical companies.
Additional information is available at www.cronuspharmausa.com
Butorphic Injection Image
PORTLAND, Ore. (AP) — Federal immigration officers shot and wounded two people in a vehicle outside a hospital in Portland, Oregon, on Thursday, a day after an officer shot and killed a driver in Minnesota, authorities said.
The shooting drew hundreds of protesters to the U.S. Immigration and Customs Enforcement building Thursday night, and Oregon Attorney General Dan Rayfield vowed to investigate “whether any federal officer acted outside the scope of their lawful authority” and to refer criminal charges to the prosecutor's office if warranted.
The Department of Homeland Security described the vehicle's passenger as “a Venezuelan illegal alien affiliated with the transnational Tren de Aragua prostitution ring” who had been involved in a recent shooting in Portland. When agents identified themselves to the occupants during a “targeted vehicle stop” Thursday afternoon, the driver tried to run them over, the department said in a written statement.
“Fearing for his life and safety, an agent fired a defensive shot,” the statement said. “The driver drove off with the passenger, fleeing the scene.”
There was no immediate independent corroboration of that account or of any gang affiliation of the vehicle's occupants. During prior shootings involving agents involved in President Donald Trump's surge of immigration enforcement in U.S. cities, including Wednesday's shooting by an ICE officer in Minneapolis, video evidence cast doubt on the administration's descriptions of what prompted the shootings.
Trump and his allies have consistently blamed Tren de Aragua for being at the root of the violence and illicit drug dealing that plague some U.S. cities.
The shooting escalates tensions in an city that has long had a contentious relationship with President Donald Trump, including Trump’s recent, failed effort to deploy National Guard troops in the city. Trump’s decision to send militarized personnel into U.S. cities to conduct immigration enforcement drew long-running nightly protests outside the ICE building in Portland.
According to the the Portland Police bureau, officers initially responded to a report of a shooting outside Adventist Health hospital at about 2:18 p.m. Thursday.
A few minutes later, police received information that a man who had been shot was asking for help in a residential area a couple of miles away. Officers then responded there and found a man and a woman with gunshot wounds. Officers determined they were injured in the shooting with federal agents, police said.
Their conditions were not immediately known. Portland police said officers applied a tourniquet to one of the wounded. Council President Elana Pirtle-Guiney said during a Portland city council meeting that "as far as we know both of these individuals are still alive and we are hoping for more positive updates throughout the afternoon.”
At a news conference Thursday night, Portland Police Chief Bob Day said the FBI was leading the investigation and that he had no details about the events that led to the shooting.
Portland Mayor Keith Wilson and the city council called on ICE to end all operations in Oregon’s largest city until a full investigation is completed.
“We stand united as elected officials in saying that we cannot sit by while constitutional protections erode and bloodshed mounts,” a joint statement said. “Portland is not a ‘training ground’ for militarized agents, and the ‘full force’ threatened by the administration has deadly consequences.”
Wilson also suggested at a news conference that he didn't necessarily believe the federal government's account of the shooting: “There was a time we could take them at their word. That time is long past.”
Democratic State Sen. Kayse Jama, who lives near the shooting scene, said Oregon is a welcoming state — but he told federal agents to leave.
“You are not welcome,” Jama said. "You need to get the hell out of Oregon.”
The city officials said “federal militarization undermines effective, community‑based public safety, and it runs counter to the values that define our region. We’ll use every legal and legislative tool available to protect our residents’ civil and human rights.”
They urged residents to show up with “calm and purpose during this difficult time.”
Several dozen people gathered Thursday evening near the scene where Portland police found the wounded people.
“It’s just been chaos," said one, Anjalyssa Jones. "The community is trying to get answers.”
U.S. Sen. Jeff Merkley, an Oregon Democrat, urged any protesters to remain peaceful.
“Trump wants to generate riots,” he said in a post on the X social media platform. “Don’t take the bait.”
Johnson reported from Seattle. Associated Press reporter Audrey McAvoy in Honolulu contributed.
Protesters and law enforcement stand outside the U.S. Immigration and Customs Enforcement facility on Thursday, Jan. 8, 2026, in Portland, Ore. (AP Photo/Jenny Kane)
A protester yells at a Portland police officer outside the U.S. Immigration and Customs Enforcement facility on Thursday, Jan. 8, 2026, in Portland, Ore. (AP Photo/Jenny Kane)
Law enforcement officials work the scene following reports that federal immigration officers shot and wounded people in Portland, Ore., Thursday, Jan. 8, 2026. (AP Photo/Jenny Kane)
A security guard stands at the scene following reports that federal immigration officers shot and wounded people in Portland, Ore., Thursday, Jan. 8, 2026. (AP Photo/Jenny Kane)
Law enforcement officials work the scene following reports that federal immigration officers shot and wounded people in Portland, Ore., Thursday, Jan. 8, 2026. (AP Photo/Jenny Kane)
Multnomah County District Attorney Nathan Vasquez, center, speaks to the media following reports that federal immigration officers shot and wounded people in Portland, Ore., Thursday, Jan. 8, 2026. (AP Photo/Jenny Kane)
Law enforcement officials work the scene following reports that federal immigration officers shot and wounded people in Portland, Ore., Thursday, Jan. 8, 2026. (AP Photo/Jenny Kane)
Law enforcement officials work the scene following reports that federal immigration officers shot and wounded people in Portland, Ore., Thursday, Jan. 8, 2026. (AP Photo/Jenny Kane)
FILE - The Department of Homeland Security (DHS) seal during a news conference June 28, 2019, in Washington. (AP Photo/Carolyn Kaster, File)
