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Trially AI Seed Round Secures $4.7M and Launches “Margo” to Solve Clinical Trial Recruitment Bottleneck

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Trially AI Seed Round Secures $4.7M and Launches “Margo” to Solve Clinical Trial Recruitment Bottleneck
News

News

Trially AI Seed Round Secures $4.7M and Launches “Margo” to Solve Clinical Trial Recruitment Bottleneck

2025-09-16 18:00 Last Updated At:18:20

KANSAS CITY, Mo.--(BUSINESS WIRE)--Sep 16, 2025--

Trially®, the AI-first clinical trial recruitment platform, today announced it has secured $4.7 million in funding and launched Margo, its agentic AI solution that multiplies trial enrollment by converting patient matches into participants.

This press release features multimedia. View the full release here: https://www.businesswire.com/news/home/20250910493277/en/

Clinical trial recruitment remains one of healthcare’s most urgent challenges: With 86% of clinical trials delayed due to recruitment failures, the pharmaceutical industry is losing over $600,000 every day while patients wait years for treatments that could save their lives.

Trially is the first fully integrated AI platform to tackle the root cause of delay. Its HIPAA-compliant LLM agents safely analyze unstructured medical data to instantly match, connect and enroll patients in relevant trials — transforming a process that once required 100s of hours of manual chart reviews and cold calling into instant enrollment opportunities.

According to ClinTrial Research’s Chief Commercial Officer, Sam Searcy, "Trially’s proprietary AI has improved our ability to pre-screen candidates, reducing the time and resources typically spent on manual EHR chart reviews while improving the diversity and quality of our patient pools.”

“Patients like James Hicks shouldn’t have to wait 10 years for life-saving treatments while trials are running in their own backyard,” said Kyle McAllister, Co-founder and CEO of Trially. “We’re bridging the gap between life-saving medicine and the people who need it now.”

Meet Margo: Agentic AI that converts patient matches into participants

Margo is the newest addition to Trially’s platform, which unifies three powerful offerings:

“Recruitment has always been the bottleneck in clinical research,” said McAllister. “With Margo, we’re not just matching patients, we’re engaging and enrolling them. That’s what sets Trially apart: we can identify patients with ~95% screening accuracy and then agentic AI can engage them at the exact moment it matters most.”

The Numbers Tell a Compelling Story:

The Seed round was led by Flyover Capital, with participation from Alpaca, Atria, Blu Ventures, Looking Glass Capital, Redbud, The Council, and Gaingels.

“Clinical trial recruitment has been the industry’s Achilles’ heel for decades,” said Thad Langford, Founding Partner at Flyover Capital. “Trially is the first solution we’ve seen that not only identifies eligible patients, but also engages and enrolls them. We’re thrilled to back Kyle and the Trially team as they accelerate access to life-saving treatments.”

With its new funding, Trially will accelerate adoption of its platform across research sites, pharmaceutical sponsors, CROs and physician networks, ensuring sponsors can avoid costly delays and patients can access life-saving treatments when it matters most.

About Trially

Trially AI is shaping the future of clinical trial recruitment by matching, engaging and enrolling qualified patients faster. Proven to multiply enrollment rates by up to 6x, reduce screen failures by 73% and automate screening with ~95% accuracy. Trially AI automates patient matching and agentic outreach from any source – including EHRs, fully compliant with HIPAA, SOC 2, FDA CFR 21 Part 11 and ISO 27001. Designed for physicians, research sites, CROs and pharmaceutical sponsors, Trially empowers you to achieve outstanding results in clinical research. For more information visit trially.ai.

Trially Founders, from left to right: Kyle McAllister, CEO & Co-founder; Ramon Prieto, CTO & Co-founder; Trevor Welch, CPO & Co-founder.

Trially Founders, from left to right: Kyle McAllister, CEO & Co-founder; Ramon Prieto, CTO & Co-founder; Trevor Welch, CPO & Co-founder.

OSLO, Norway (AP) — King Haakon VIII pledged an oath of allegiance to Norway's constitution in parliament on Tuesday, an important symbolic step as he takes over at the helm of the Scandinavian country after his late father's 35-year reign.

Haakon became Norway's monarch when King Harald V died on Friday at age 89. He has adopted the motto “All for Norway,” which dates back to his great-grandfather.

He was driven the short distance from the royal palace to the Storting, or parliament, in an open car. There, Speaker Masud Gharahkhani read the official announcement of Harald's death and Haakon's succession.

Haakon, 53, then took the oath.

“I promise and swear that I will govern the kingdom of Norway in accordance with its constitution and laws; so help me God, the almighty and omniscient,” he said.

Norway’s monarchy has old roots, tracing its origins to King Harald Fairhair in the ninth century. When Norway regained its independence from Sweden in 1905, three-quarters of voters in a national plebiscite approved restoring the monarchy.

Today, its role is largely symbolic as power lies with the elected government and parliament, but the Norwegian royal family retains a role in promoting the wealthy nation around the world.

On Monday, Harald's coffin was taken to the chapel of the royal palace in downtown Oslo, where it will remain until his funeral on Sept. 9.

From Tuesday afternoon until Sept. 8, the chapel will be open every day for the public to pay their last respects by filing past the coffin. The royal palace said in a statement that visitors aren't allowed to take photos or film inside the chapel, and that they can't leave flowers or other items.

Haakon's wife, Queen Mette-Marit, joined Monday's coffin procession in her first official appearance since assuming the title. She has been largely absent from the public eye following her lung transplant in June.

Before Haakon's pledge of allegiance, the palace said that Mette-Marit wasn't going to the ceremony. In a statement, it quoted Are Holm, a pulmonologist at Oslo's University Hospital, as saying that complications following a transplant aren't uncommon and that Mette-Marit has experienced them on several occasions, “including today.”

"As a result, the Queen must remain under observation throughout the day. Unfortunately, the Queen will therefore be unable to attend the swearing-in ceremony at the Storting today,” he said.

King Haakon VIII. takes the oath according to the Constitution in the Storting, Norway's parliament, accompanied by Crown Princess Ingrid Alexandra, right, in Oslo, Norway, Tuesday, Sept. 1, 2026. (Hakon Mosvold Larsen/Pool Photo via AP)

King Haakon VIII. takes the oath according to the Constitution in the Storting, Norway's parliament, accompanied by Crown Princess Ingrid Alexandra, right, in Oslo, Norway, Tuesday, Sept. 1, 2026. (Hakon Mosvold Larsen/Pool Photo via AP)

King Haakon VIII. arrives to take the oath according to the Constitution in the Storting, Norway's parliament, in Oslo, Norway, Tuesday, Sept. 1, 2026. (Cornelius Poppe/NTB Scanpix via AP)

King Haakon VIII. arrives to take the oath according to the Constitution in the Storting, Norway's parliament, in Oslo, Norway, Tuesday, Sept. 1, 2026. (Cornelius Poppe/NTB Scanpix via AP)

King Haakon VIII., front, arrives to take the oath according to the Constitution in the Storting, Norway's parliament, in Oslo, Norway, Tuesday, Sept. 1, 2026. (Ole Berg-Rusten/Pool Photo via AP)

King Haakon VIII., front, arrives to take the oath according to the Constitution in the Storting, Norway's parliament, in Oslo, Norway, Tuesday, Sept. 1, 2026. (Ole Berg-Rusten/Pool Photo via AP)

King Haakon VIII., left, takes the oath according to the Constitution in the Storting, Norway's parliament, accompanied by Crown Princess Ingrid Alexandra, right, in Oslo, Norway, Tuesday, Sept. 1, 2026. (Hakon Mosvold Larsen/Pool Photo via AP)

King Haakon VIII., left, takes the oath according to the Constitution in the Storting, Norway's parliament, accompanied by Crown Princess Ingrid Alexandra, right, in Oslo, Norway, Tuesday, Sept. 1, 2026. (Hakon Mosvold Larsen/Pool Photo via AP)

FILE - Norway's King Harald arrives at a central London hotel for a pre-royal wedding dinner hosted by Lady Elizabeth Anson and attended by members of the British royal family and foreign royal families, in London, on April, 28, 2011. (AP Photo/Alastair Grant, File)

FILE - Norway's King Harald arrives at a central London hotel for a pre-royal wedding dinner hosted by Lady Elizabeth Anson and attended by members of the British royal family and foreign royal families, in London, on April, 28, 2011. (AP Photo/Alastair Grant, File)

Norway's King Haakon reads greetings, that mourners have laid down in front of the Palace four days after the death of King Harald V., in Oslo Monday, Aug. 31, 2026. (Javad Parsa/NTB Scanpix via AP)

Norway's King Haakon reads greetings, that mourners have laid down in front of the Palace four days after the death of King Harald V., in Oslo Monday, Aug. 31, 2026. (Javad Parsa/NTB Scanpix via AP)

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