SANTA CLARA, Calif. (AP) — San Francisco star defensive end Nick Bosa left the win over the Arizona Cardinals with a knee injury in the first half and the 49ers are waiting for word on the extent of the injury.
Bosa left the field favoring his right leg after a third-down pass rush in the first quarter. He went immediately to the medical tent and appeared to give a thumbs-down signal to someone in the crowd.
Bosa tested the knee briefly on the sideline before going back to the locker room. He was ruled out of the game at halftime.
Coach Kyle Shanahan said initial tests did not show a tear of Bosa's ACL, but he will need more tests to completely rule that out and to learn the severity of the injury.
“There is concern because of how he feels,” Shanahan said. “They did the tests and stuff on the sideline. Usually they say whether he definitely did or not. They didn’t say that. But we are concerned with that and keeping our fingers crossed for the MRI.”
San Francisco rookie defensive end Mykel Williams also went back to the locker room in the first half with a wrist injury, but quickly returned. Williams and fellow rookies Alfred Collins and C.J. West helped San Francisco pull out a 16-15 victory.
“Anytime you lose a guy like Nick and he doesn’t come back, that’s a real buzzkill,” left tackle Trent Williams said. “We’re hoping and praying that we get some good news. It’s cliche to say it’s a next man up league, but when you lose a guy like that, you need three or four guys to come in.”
Bosa won the AP NFL Defensive Player of the Year award in 2022 and is one of the most important players on the 49ers. He had two sacks in the first two games this season and has 64 1/2 in his career.
Bosa has made the Pro Bowl in five of his six seasons in the NFL, missing only in 2020 when he went down with a season-ending knee injury in Week 2.
“Obviously he’s one of our best players, so it would be a huge loss,” linebacker Fred Warner said. “I’m hoping for the best news.”
The Niners have been missing several of their biggest stars with tight end George Kittle on injured reserve after hurting his hamstring in the season opener, No. 1 receiver Brandon Aiyuk on the physically unable to perform list recovering from knee surgery and quarterback Brock Purdy missing two games with a toe injury.
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San Francisco 49ers defensive end Nick Bosa takes the field prior to an NFL football game against the Arizona Cardinals, Sunday, Sept. 21, 2025, in Santa Clara. (AP Photo/Sergio Estrada)
San Francisco 49ers defensive end Nick Bosa walks off the field during the first half of an NFL football game against the Arizona Cardinals, Sunday, Sept. 21, 2025, in Santa Clara, Calif. (AP Photo/Godofredo A. Vásquez)
NUUK, Greenland (AP) — U.S. President Donald Trump has turned the Arctic island of Greenland into a geopolitical hotspot with his demands to own it and suggestions that the U.S. could take it by force.
The island is a semiautonomous region of Denmark, and Denmark's foreign minister said Wednesday after a meeting at the White House that a “ fundamental disagreement ” remains with Trump over the island.
The crisis is dominating the lives of Greenlanders and "people are not sleeping, children are afraid, and it just fills everything these days. And we can’t really understand it,” Naaja Nathanielsen, a Greenlandic minister said at a meeting with lawmakers in Britain’s Parliament this week.
Here's a look at what Greenlanders have been saying:
Trump has dismissed Denmark’s defenses in Greenland, suggesting it’s “two dog sleds.”
By saying that, Trump is “undermining us as a people,” Mari Laursen told AP.
Laursen said she used to work on a fishing trawler but is now studying law. She approached AP to say she thought previous examples of cooperation between Greenlanders and Americans are “often overlooked when Trump talks about dog sleds.”
She said during World War II, Greenlandic hunters on their dog sleds worked in conjunction with the U.S. military to detect Nazi German forces on the island.
“The Arctic climate and environment is so different from maybe what they (Americans) are used to with the warships and helicopters and tanks. A dog sled is more efficient. It can go where no warship and helicopter can go,” Laursen said.
Trump has repeatedly claimed Russian and Chinese ships are swarming the seas around Greenland. Plenty of Greenlanders who spoke to AP dismissed that claim.
“I think he (Trump) should mind his own business,” said Lars Vintner, a heating engineer.
“What's he going to do with Greenland? He speaks of Russians and Chinese and everything in Greenlandic waters or in our country. We are only 57,000 people. The only Chinese I see is when I go to the fast food market. And every summer we go sailing and we go hunting and I never saw Russian or Chinese ships here in Greenland,” he said.
Down at Nuuk's small harbor, Gerth Josefsen spoke to AP as he attached small fish as bait to his lines. He said, “I don't see them (the ships)” and said he had only seen “a Russian fishing boat ten years ago.”
Maya Martinsen, 21, a shop worker, told AP she doesn't believe Trump wants Greenland to enhance America's security.
“I know it’s not national security. I think it’s for the oils and minerals that we have that are untouched,” she said, suggesting the Americans are treating her home like a “business trade.”
She said she thought it was good that American, Greenlandic and Danish officials met in the White House Wednesday and said she believes that “the Danish and Greenlandic people are mostly on the same side,” despite some Greenlanders wanting independence.
“It is nerve-wrecking, that the Americans aren’t changing their mind,” she said, adding that she welcomed the news that Denmark and its allies would be sending troops to Greenland because “it’s important that the people we work closest with, that they send support.”
Tuuta Mikaelsen, a 22-year-old student, told AP that she hopes the U.S. got the message from Danish and Greenlandic officials to “back off.”
She said she didn't want to join the United States because in Greenland “there are laws and stuff, and health insurance .. .we can go to the doctors and nurses ... we don’t have to pay anything,” she said adding "I don’t want the U.S. to take that away from us.”
In Greenland's parliament, Juno Berthelsen, MP for the Naleraq opposition party that campaigns for independence in the Greenlandic parliament told AP that he has done multiple media interviews every day for the last two weeks.
When asked by AP what he would say to Trump and Vice President JD Vance if he had the chance, Berthelsen said:
“I would tell them, of course, that — as we’ve seen — a lot of Republicans as well as Democrats are not in favor of having such an aggressive rhetoric and talk about military intervention, invasion. So we would tell them to move beyond that and continue this diplomatic dialogue and making sure that the Greenlandic people are the ones who are at the very center of this conversation.”
“It is our country,” he said. “Greenland belongs to the Greenlandic people.”
Kwiyeon Ha and Evgeniy Maloletka contributed to this report.
FILE - A woman pushes a stroller with her children in Nuuk, Greenland, Thursday, Jan. 15, 2026. (AP Photo/Evgeniy Maloletka, File)
Military vessel HDMS Knud Rasmussen of the Royal Danish Navy patrols near Nuuk, Greenland, Thursday, Jan. 15, 2026. (AP Photo/Evgeniy Maloletka)
Juno Berthelsen, MP for the Naleraq opposition party that campaigns for independence in the Greenlandic parliament poses for photo at his office in Nuuk, Greenland, Thursday, Jan. 15, 2026. (AP Photo/Evgeniy Maloletka)
Fisherman Gerth Josefsen prepares fishing lines at the harbour of Nuuk, Greenland, Wednesday, Jan. 14, 2026. (AP Photo/Evgeniy Maloletka)
A woman walks on a street past a Greenlandic national flag in Nuuk, Greenland, Wednesday, Jan. 14, 2026. (AP Photo/Evgeniy Maloletka)
