GE HealthCare’s Photonova™ Spectra with Deep Silicon reimagines photon-counting CT to see more, know more and achieve more

CHICAGO--(BUSINESS WIRE)--Nov 24, 2025--

GE HealthCare today announced the submission of a 510(k) to the U.S. FDA seeking clearance for Photonova™ Spectra, i its new photon-counting computed tomography (PCCT) system with advanced AI algorithms ii – marking a major milestone in the company’s decades-long history of CT innovation. Built on GE HealthCare’s proprietary Deep Silicon detector technology, Photonova Spectra is designed to deliver remarkable spectral and spatial resolution for ultra-high-definition (UHD) imaging with wide coverage, seeking to enable fast acquisition speeds, precise visualization of anatomical structures and enhanced material separation.

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Photon counting CT represents a transformative advancement in medical imaging. Unlike conventional CT systems that convert X-rays into light before measuring them, photon counting CT directly counts individual X-ray photons and measures their energy, enabling the potential for higher spectral and spatial resolution and improved tissue characterization. This process makes it possible to give clinicians more information and confidence to help detect and diagnose disease. Photonova Spectra takes this innovation further by using Deep Silicon, a novel detector material that is designed to bring enhanced spectral imaging, aiming to support advanced lesion characterization and treatment monitoring with CT.

“Today marks a transformative leap for GE HealthCare and a bold new chapter in CT innovation. Photonova Spectra is more than a new product – it’s a demonstration of what’s possible when vision meets purposeful design,” says Peter Arduini, President & CEO of GE HealthCare. “Built to give healthcare teams the clarity and confidence they need, this system aims to redefine decision-making and care delivery – meeting today’s challenges and tomorrow’s possibilities. This is innovation with impact designed to reshape workflows, sharpen image quality and empower confident, timely decisions. I am immensely proud of our teams and collaborators who are transforming the future of CT and bringing precision care to life.”

In today’s fast-paced healthcare environment clinicians need definitive answers, especially as patient volumes rise iii and diagnostic complexity increases. iv GE HealthCare’s Photonova Spectra was intentionally engineered to address these challenges. Harnessing the full potential of its proprietary Deep Silicon detectors, the system’s UHD imaging is designed to deliver wide coverage, enabling fast acquisition speeds and the precise visualization of subtle tissue variations, small lesions and vascular structures. With on-demand spectral imaging for every scan, it also seeks to empower clinicians to detect, characterize and monitor disease with confidence. Staff can also rely on one protocol setup for many exams, reducing complexity and supporting efficiency. Altogether, these capabilities aim to deliver clinicians the information they need in one exam and enable fast, confident diagnoses and treatment planning.

Deep Silicon powers precision across care pathways

Silicon stands out as a high-performing semiconductor material due to its purity and structural consistency. When interacting with X-ray photons, its unique composition enables the precise measurement of photon energy and delivers high levels of energy resolution – critical for advanced image reconstruction. This capability can allow clinicians to obtain images with high contrast, impressive low-contrast detectability and improved material characterization for potentially greater diagnostic confidence.

Leveraging GE HealthCare’s innovative Deep Silicon detector design, Photonova Spectra aims to enhance image quality by reducing signal overload and improving energy separation. This enables GE HealthCare’s photon counting CT system to clearly distinguish between different materials such as iodine, calcium and fat with remarkable precision. Additionally, its wide detector coverage and rapid rotation speed (0.23 seconds) support fast acquisition and motion-free imaging – even in challenging patient scenarios.

“Photon counting CT is a fundamentally different approach to imaging. It can be thought of as particle physics in action,” shares Giuseppe Toia, MD, Assistant Professor of Radiology, Associate Section Chief of Abdominal Imaging and Intervention and Program Director of Abdominal Imaging and Intervention Fellowship with the Department of Radiology at the University of Wisconsin School of Medicine and Public Health. “Being involved in developing and testing the Deep Silicon detector has allowed us to assess how the technology can be applied to address common issues such as improving spatial resolution and attaining accurate CT numbers. The goal of using photon counting CT is to help differentiate materials and reveal diagnostic details, which is of interest to radiologists for informed clinical decision-making and streamlined workflows.”

The clinical potential of Photonova Spectra with Deep Silicon spans a wide range of specialties, with the technology’s design seeking to unlock new levels of clarity, detail and diagnostic confidence.

The system’s clinical design goals include:

Photonova Spectra’s advanced photon counting architecture and Deep Silicon detector design also aim to open new possibilities for research in areas such as quantitative imaging, tissue characterization and spectral biomarker discovery. Additionally, researchers may explore novel clinical applications and imaging protocols that were previously limited by conventional CT technology.

Harnessing up to 50x more data v for an effortless workflow

GE HealthCare’s Photonova Spectra is designed to maximize the vast amounts of data provided, harnessing up to 50 times more data than conventional CT v with the help of NVIDIA’s accelerated computing technology to enable advanced reconstruction techniques and precise outputs with the aim of supporting enhanced clinical decision-making and smooth workflows.

“Accelerated computing and AI are the essential engines driving the transformation of medical imaging today, moving us from passive data capture to active, intelligent clinical workflows,” notes Kimberly Powell, Vice President of Healthcare at NVIDIA. “By working on the technology’s development and pursuing opportunities to pair GE HealthCare’s Deep Silicon architecture with NVIDIA’s Blackwell platform in the future, we aim to unlock the full potential of spectral imaging – turning massive volumes of data into actionable insights. This collaboration is helping reshape what is possible in diagnostic imaging and aiming to set a new standard for clinical efficiency and precision.”

“Engineered with purpose to tackle some of healthcare’s most complex challenges – Photonova Spectra represents the next generation of CT innovation. From our earliest breakthroughs to today’s newest wave of innovation, GE HealthCare has innovated with intention, delivering technologies that empower clinicians and transform care,” shares Roland Rott, President and CEO, Imaging, GE HealthCare. “As pioneers in AI and medical devices, we have harnessed advanced algorithms to materially enable this product – combining photon counting CT with our proprietary Deep Silicon detector. We are not just aiming to advance image quality, but to redefine diagnostic confidence and shape the future of precision medicine.”

Photonova Spectra also aims to simplify the entire CT process with Effortless Workflow with universal full fidelity scan, which enables a one-scan approach to reduce exam-specific protocols and enable automated reconstruction of ultra-high-resolution spectral images on demand. Its intuitive CT ONE operator environment and automated features – including Auto Positioning – aim to help improve consistency across GE HealthCare systems, while its full-detector coverage and Deep Silicon design help deliver impressive image quality.

For more information on GE HealthCare’s new Photonova Spectra photon counting CT with Deep Silicon detectors, please visit gehealthcare.com or stop by the company’s booth (7334) at the Radiological Society of North America (RSNA) in Chicago.

About GE HealthCare Technologies Inc.

GE HealthCare is a trusted partner and leading global healthcare solutions provider, innovating medical technology, pharmaceutical diagnostics, and integrated, cloud-first AI-enabled solutions, services and data analytics. We aim to make hospitals and health systems more efficient, clinicians more effective, therapies more precise and patients healthier and happier. Serving patients and providers for more than 125 years, GE HealthCare is advancing personalized, connected and compassionate care, while simplifying the patient’s journey across care pathways. Together, our Imaging, Advanced Visualization Solutions, Patient Care Solutions and Pharmaceutical Diagnostics businesses help improve patient care from screening and diagnosis to therapy and monitoring. We are a $19.6 billion business with approximately 51,000 colleagues working to create a world where healthcare has no limits.

GE HealthCare is proud to be among 2025 Fortune World’s Most Admired Companies™.

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Photonova Spectra is 510(k)-pending with the U.S. FDA. Not CE Marked. Not available for sale in the United States, Europe, Canada, or any other region.

NEW YORK (AP) — Walmart delivered another quarter of impressive sales with speedy deliveries and low prices becoming a strong magnet for people across the income spectrum that are spending more on almost everything, particularly gasoline.

Yet like other major retailers posting financial results this week, Walmart was cautious about the rest of the year given the current economic uncertainty. On Thursday, it issued a forecast for the current quarter that was weaker than what Wall Street had been expecting.

Shares slipped about 7% Thursday.

Walmart has resonated with many Americans who are increasingly careful about where they spend their money as inflation takes a bigger bite out of paychecks, notably gasoline which has soared since the start of the Iran war in late February. Walmart can serve as a barometer of consumer spending given its vast customer base. More than 150 million customers are on its website or in its stores every week, according to Walmart.

One telling shift during the quarter that captures the stress many Americans are feeling: The number of gallons that customers put in their cars during visits to U.S. Walmart and Sam’s Club gas stations fell below 10 for the first time since 2022, which was the midst of the COVID-19 pandemic.

“That’s an indication of stress,” said Chief Financial Officer John David Rainey.

Walmart touted strong sales that were fueled by online shopping on Thursday.

Comparable sales at U.S. Walmart stores rose 4.1% during the three-month period ended April 30. Walmart’s U.S online sales rose 26%, the company said.

Walmart’s promise of lower prices, faster delivery and a refresh of its merchandise has attracted wealthier shoppers. The biggest gains in market share for Walmart are coming from households with annual income over $100,000. That shift is taking place as lower-income shoppers become more entrenched in what economists collectively call a K-shaped economy.

“We see with our customers that the high-income customer is spending with confidence into many categories, while the lower income consumer is more budget conscious and perhaps navigating financial distress,” Rainey told analysts on Thursday.

Rainey told analysts that higher fuel prices took a bite out of profits as it was forced to absorb higher transportation costs. And while the company is focused on offering low prices, Walmart may raise prices later if fuel costs remain high, he said.

U.S. retailers have spent months navigating an uncertain economic environment, from President Donald Trump’s tariffs to the impact of soaring gasoline prices due to the war. The average price for a gallon of regular gasoline raced higher this week and did so again overnight. Gasoline prices are about 45% above where they were at this time last year.

Based on quarterly financial reports from Walmart, Target, Home Depot, Lowe's and TJX, shoppers are cautious but still spending, helped by more generous tax refunds. Yet there is a widespread belief among economists that once those refunds dry up, shoppers will pull back on spending. Consumer spending is the dominant economic engine for the U.S., and retreat would have broad implications for the U.S.

Target reported the largest jump in comparable sales in four years Wednesday, but a cautious outlook overshadowed rather convincing evidence that changes under the company’s new CEO are landing solidly with customers. Target raised its annual revenue outlook Wednesday, but it was still below the pace of its first quarter this year.

The nation’s two largest home improvement retailers Home Depot and Lowe’s reported strong sales, but both companies said that customers are putting off larger home projects.

“I think, overall, this has been the most difficult housing market that I’ve faced in this business since the financial crisis,” Lowe’s CEO Marvin Ellison said this week.

Walmart, based in Bentonville, Arkansas reported first-quarter earnings of $5.33 billion, or 67 cents, for the quarter ended April 30. Adjusted per-share results were 66 cents, matching the 66 cents that analysts expected, according to FactSet.

For the year-ago quarter, the company reported net income of $4.48 billion, or 56 cents per share.

Sales rose 7.3% to $177.75 billion in the fiscal first quarter, above the $174.84 billion that analysts predicted.

Walmart said higher fuel prices took a bite out of profits as it was forced to absorb higher transportation costs.

The company highlighted its speedier deliveries, which is driving more shoppers to buy more often. Rainey said that roughly 60% of U.S. online deliveries arrive at customers' homes in 30 minutes or less.

For the second quarter, Walmart expects sales to be 4% to 5% higher than the same period a year ago. It also expects per-share profit to be between 72 cents and 74 cents. Analysts had been projecting per-share earns of 75 cents on sales of $186.2 billion, according to FactSet.

Walmart stuck to the annual guidance that it issued in February.

Drones operated by Zipline leave base to make deliveries from a Walmart store in Pea Ridge, Ark., Friday, Sept. 26, 2025. (AP Photo/Charlie Riedel)