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Niagen Bioscience Launches Niagen® Skincare Innovation Lab and Debuts Dermatologist-Tested Niagen NanoCloud™, From Tru Niagen Powered by Patented Niagen®

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Niagen Bioscience Launches Niagen® Skincare Innovation Lab and Debuts Dermatologist-Tested Niagen NanoCloud™, From Tru Niagen Powered by Patented Niagen®
News

News

Niagen Bioscience Launches Niagen® Skincare Innovation Lab and Debuts Dermatologist-Tested Niagen NanoCloud™, From Tru Niagen Powered by Patented Niagen®

2026-03-10 20:32 Last Updated At:20:50

LOS ANGELES--(BUSINESS WIRE)--Mar 10, 2026--

Niagen Bioscience, Inc. (NASDAQ: NAGE), the global authority on NAD+ (nicotinamide adenine dinucleotide) with a focus on the science of healthy aging, today announced the launch of Niagen®Skincare Innovation Lab, a new product innovation platform designed to translate the Company’s leadership in NAD+ science into category-defining skincare. Debuting under the platform is Niagen NanoCloud™, a limited-release, dermatologist-tested topical skincare product powered by Niagen Bioscience’s flagship ingredient, Niagen ® (patented nicotinamide riboside, or NR), created to generate consumer insights and help shape future topical innovation within the Company’s core Tru Niagen ® portfolio.

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Niagen NanoCloud sachets visibly improve skin texture, hydration, and radiance

Niagen NanoCloud sachets visibly improve skin texture, hydration, and radiance

The Niagen Nanocloud's sealed, waterless format helps keep Niagen intact until use.

The Niagen Nanocloud's sealed, waterless format helps keep Niagen intact until use.

Niagen NanoCloud™ sachets, a limited-release, precision-dosed topical skincare prototype powered by Niagen Bioscience’s flagship ingredient, Niagen®

Niagen NanoCloud™ sachets, a limited-release, precision-dosed topical skincare prototype powered by Niagen Bioscience’s flagship ingredient, Niagen®

Niagen Bioscience Launches Niagen® Skincare Innovation Labs and Debuts Niagen NanoCloud™, the First Topical Product Powered by Patented Niagen®

Niagen Bioscience Launches Niagen® Skincare Innovation Labs and Debuts Niagen NanoCloud™, the First Topical Product Powered by Patented Niagen®

This press release features multimedia. View the full release here: https://www.businesswire.com/news/home/20260310114165/en/

Rob Fried, Chief Executive Officer of Niagen Bioscience, commented, “Niagen Skincare Innovation Lab is a strategic step into exploring how Niagen can extend into new consumer categories. With Niagen NanoCloud, we are introducing our first topical prototype in a format designed to protect potency, generate consumer insight, and help inform future product development.”

Niagen NanoCloud is the inaugural release from the Niagen Skincare Innovation Lab. The Innovation Lab was designed to address a core challenge in NAD+ skincare: water-based NAD+ and precursor products on the market can degrade rapidly, long before they ever reach the skin, because the molecules are unstable in water. Niagen Bioscience intends to continue evolving Niagen Skincare Innovation Labs to address unmet needs in skincare formulation and product development. The Niagen NanoCloud sachet’s sealed, waterless format helps keep Niagen intact until the moment of use, ensuring optimal efficacy. When mixed with a serum or moisturizer, the sachet dissolves to deliver a freshly activated, precision-dosed treatment that visibly improves texture, hydration, and radiance.

The Niagen NanoCloud sachets are formulated with a curated blend of ingredients designed to support healthy-looking, hydrated skin. At the core is Niagen, the most efficient, effective, well-researched, patented, and high-quality NAD+ boosters available. Additional key ingredients include hyaluronic acid (sodium hyaluronate) for hydration, pullulan to help smooth texture and support a more refined appearance, squalane to nourish and soften without greasiness, and vitamin E to provide antioxidant support and help maintain the skin barrier.

A consumer perception study found that with consistent use, skin appears smoother, more hydrated, and more youthful-looking, with visible results starting in as few as 2 weeks.¹

The launch marks Niagen Bioscience’s entry into the global skincare category, which Fortune Business Insights valued at $122.11 billion USD in 2025 and projected to grow to $227.13 billion USD by 2034. Within that broader opportunity, the global anti-aging cosmetics market was estimated at $60.11 billion USD in 2025 and is projected to reach $106.98 billion USD by 2035, according to Precedence Research, while the global topical NAD+ product market “is expected to grow at a CAGR of 16.4% from 2025 to 2030" ( Grand View Research ), underscoring growing demand for science-backed solutions at the intersection of skincare, wellness, and healthy aging.

The limited-release Niagen NanoCloud is now available on truniagen.com for $59, with each unit containing 30 individual sachets.

For additional information on Niagen, visit www.niagenbioscience.com.

​​¹Based on a 6-week consumer perception study of 37 female participants aged 35+ who applied the product twice daily. Combined agree/strongly agree responses on a 5-point Likert scale. Individual results may vary.

About Niagen Bioscience:

Niagen Bioscience, Inc. (NASDAQ: NAGE) is the global leader in NAD+ (nicotinamide adenine dinucleotide) science and healthy-aging research. As a trusted pioneer of NAD+ discoveries, Niagen Bioscience™ is dedicated to advancing healthspan through precision science and innovative NAD+-boosting solutions.

The Niagen Bioscience team, composed of world-renowned scientists, works with independent investigators from esteemed universities and research institutions around the globe to uncover the full potential of NAD+. A vital coenzyme found in every cell of the human body, NAD+ declines with age and exposure to everyday lifestyle stressors. NAD+ depletion is a key contributor to age-related changes in health and vitality.

Distinguished by state-of-the-art laboratories, rigorous scientific and quality protocols, and collaborations with leading research institutions worldwide, Niagen Bioscience sets the gold standard for research, quality, and innovation. There’s a better way to age.

At the heart of its clinically proven product portfolio is Niagen® (patented nicotinamide riboside, or NR), the most efficient, well-researched, and high-quality NAD+ booster available. Niagen powers the Company’s consumer supplement, Tru Niagen®, the number one NAD+ boosting oral supplement in the United States† (available at www.truniagen.com ), and Niagen™ Plus, featuring pharmaceutical-grade intravenous (IV) and injectable Niagen products ( www.niagenplus.com ). Pharmaceutical-grade Niagen IV and injections are compounded and distributed by U.S. FDA-registered 503B outsourcing facilities and are available exclusively at clinics with a prescription.

Niagen Bioscience’s robust patent portfolio protects NR and other NAD+ precursors. Niagen Bioscience maintains a website at www.niagenbioscience.com, where copies of press releases, news, and financial information are regularly published.

Based on revenue per largest U.S. e-commerce marketplace (Jan. 2025 – Dec. 2025)

Forward Looking Statements:

This release contains forward-looking statements within the meaning of Section 27A of the Securities Act of 1933, and Section 21E of the Securities Exchange Act of 1934. Statements that are not a description of historical facts constitute forward-looking statements and may often, but not always, be identified by the use of such words as “expects,” “anticipates,” “intends” “estimates,” “plans,” “potential,” “possible,” “probable,” “believes” “seeks,” “may,” “will,” “should,” “could,” “predicts,” “projects,” “continue,” “would” or the negative of such terms or other similar expressions.

Forward-looking statements are based on current expectations and assumptions and are subject to risks and uncertainties that could cause actual results to differ materially from those described. These risks and uncertainties include, but are not limited to, inflationary conditions and adverse economic conditions; our history of operating losses; the growth and profitability of our product sales; our ability to maintain and grow sales, marketing and distribution capabilities; changing consumer perceptions of our products; our reliance on a single or limited number of third-party suppliers; risks of conducting business in China; including unanticipated developments in and risks related to the Company’s ability to secure adequate quantities of pharmaceutical-grade Niagen in a timely manner; the Company’s ability to obtain appropriate contracts and arrangements with U.S. FDA-registered 503B outsourcing facilities required to compound and distribute pharmaceutical-grade Niagen to clinics; the Company’s ability to remain on the U.S. FDA Bulk Drug Substances Nominated for Use in Compounding Under Section 503B of the Federal Food, Drug, and Cosmetic Act Category 1 list; the Company’s ability to maintain and enforce the Company’s existing intellectual property and obtain new patents; whether the potential benefits of NRC can be further supported; further research and development and the results of clinical trials possibly being unsuccessful or insufficient to meet applicable regulatory standards or warrant continued development; the ability to enroll sufficient numbers of subjects in clinical trials; determinations made by the FDA and other governmental authorities, including with respect to products seeking to compete in our market; mislabeling or other misleading marketing practices by competitors; economic and market instability, including as a result of tariffs or trade conflicts; and the risks and uncertainties associated with our business and financial condition in general, described in our filings with the Securities and Exchange Commission (SEC), including, without limitation, our most recent Annual Report on Form 10-K and Quarterly Report on Form 10-Q as filed with the SEC.

Readers are cautioned not to place undue reliance on these forward-looking statements, which speak only as of the date hereof, and actual results may differ materially from those suggested by these forward-looking statements. All forward-looking statements are qualified in their entirety by this cautionary statement and Niagen Bioscience undertakes no obligation to revise or update this release to reflect events or circumstances after the date hereof.

Niagen NanoCloud sachets visibly improve skin texture, hydration, and radiance

Niagen NanoCloud sachets visibly improve skin texture, hydration, and radiance

The Niagen Nanocloud's sealed, waterless format helps keep Niagen intact until use.

The Niagen Nanocloud's sealed, waterless format helps keep Niagen intact until use.

Niagen NanoCloud™ sachets, a limited-release, precision-dosed topical skincare prototype powered by Niagen Bioscience’s flagship ingredient, Niagen®

Niagen NanoCloud™ sachets, a limited-release, precision-dosed topical skincare prototype powered by Niagen Bioscience’s flagship ingredient, Niagen®

Niagen Bioscience Launches Niagen® Skincare Innovation Labs and Debuts Niagen NanoCloud™, the First Topical Product Powered by Patented Niagen®

Niagen Bioscience Launches Niagen® Skincare Innovation Labs and Debuts Niagen NanoCloud™, the First Topical Product Powered by Patented Niagen®

NEW YORK & SANTIAGO, Chile--(BUSINESS WIRE)--Mar 10, 2026--

trii, a leading investing app in Latin America, today announced the launch of US stock trading in Chile, introducing a mobile-first solution that aims to remove traditional barriers to investing in the Chilean market. The launch is powered by Alpaca, a global leader in brokerage infrastructure APIs, providing access to options, stocks, ETFs, fixed income, and crypto.

This press release features multimedia. View the full release here: https://www.businesswire.com/news/home/20260310917635/en/

Retail investors across Latin America have faced significant hurdles to market participation, including high commission fees, limited financial education, and limited technological and market infrastructure. In Chile, while interest in wealth creation is growing, many potential investors remain intimidated by traditional brokerages. Recent data shows that more than 62% of Chileans find it difficult to invest their money, citing a lack of knowledge and awareness of accessible tools.

trii is addressing these challenges through their intuitive interface, low commissions and fees, and integrated financial education. Through the partnership between trii and Alpaca, hundreds of thousands of Chilean retail investors can now access the US markets, diversify away from local currency risks and political cycles, and gain global exposure. By making investing affordable, trii is making wealth building accessible to their users’ everyday financial life, not a one-time, high-pressure decision.

"US stocks open a completely different level of opportunity for our customers,” said Carlos Guayara, Founder of trii. “By giving access to the US market, we have removed the constraints of investing only in the local market while exposing customers to a broader set of companies with better liquidity and more efficient pricing. That alone already changes the investing experience."

“Working with Alpaca, an API-driven infrastructure partner, gave us the flexibility to integrate US stock trading without compromising on simplicity or speed,” added Guayara. “This allowed us to move faster and focus on what we do best, which is product, education, and user experience, while relying on proven execution and market access on the backend. With Alpaca, we are building trii to be an investment marketplace where people across LATAM can access reliable, scalable investment services while keeping a consistent experience for our customers."

"We are thrilled to support trii as they expand into Chile," said Yoshi Yokokawa, Co-founder and CEO of Alpaca. "Beyond providing the technology and reliable infrastructure they need to scale, we’re excited to support trii’s goal of giving more people easy, affordable access to the stock market. Together, we want to make investing simple and accessible for everyone across Chile and the broader LATAM region.”

With the launch of US stocks, trii is aiming to increase the number of Chilean investors while taking another step in its broader strategy to become LATAM’s brokerage of choice.

About Alpaca

Alpaca is a US-headquartered, self-clearing broker-dealer and a global leader in brokerage infrastructure APIs providing access to stocks, ETFs, options, fixed income, and crypto. Alpaca delivers embeddable finance solutions for tokenization, fully paid securities lending, high-yield cash, 24/5 trading, Shariah-compliant investing, and more. Today, Alpaca powers over 10 million brokerage accounts across hundreds of fintechs and institutions in 40+ countries with over $320M in funding. For more information, visit: alpaca.markets

About trii

trii is a mobile-first investment platform dedicated to democratizing access to the stock market in Latin America. Through its easy-to-use app, trii offers local and international stock trading, educational content, and low-cost entry points for retail investors. For more information, visit trii.co

AlpacaDB, Inc., the parent company of Alpaca Securities LLC and Alpaca Crypto LLC, provides services and technology, including the brokerage infrastructure API supporting Alpaca’s financial services.

Securities brokerage services are provided by Alpaca Securities LLC (dba “Alpaca Clearing”), memberFINRA/SIPC, a wholly owned subsidiary of AlpacaDB, Inc.

Cryptocurrency services are provided by Alpaca Crypto LLC, a FinCEN-registered MSB (NMLS #2160858) and subsidiary of AlpacaDB, Inc.

This is not an offer, solicitation of an offer, or advice to buy or sell securities or cryptocurrencies or open a brokerage account or cryptocurrency account in any jurisdiction where Alpaca Securities or Alpaca Crypto, respectively, are not registered or licensed, as applicable.

All investments involve risk; for more information, please see ourDisclosure Library.

trii Launches US Stock Trading in Chile, Expanding Global Investment Access with Alpaca

trii Launches US Stock Trading in Chile, Expanding Global Investment Access with Alpaca

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