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The Mantle-Aave-Bybit integration delivers record-breaking on-chain liquidity, driven by coordinated incentive programs and deep CeDeFi infrastructure.
DUBAI, UAE, Feb. 25, 2026 /PRNewswire/ -- Following the successful mainnet integration between Mantle and Aave, announced in collaboration with Bybit, Mantle and Aave today announced that their joint deployment has surpassed $575 million in total market size, encompassing both supply and borrows within just two weeks of going live.
The milestone reflects the growing demand for institutional-grade DeFi infrastructure and marks one of the fastest liquidity ramp-ups in Aave's deployment history across any network.
The integration, which brought together Mantle's high-performance distribution layer, Aave's leading decentralized liquidity markets, and Bybit's global exchange infrastructure, has established a unified framework for on-chain finance that bridges centralized and decentralized ecosystems at scale. What began as a protocol deployment has rapidly evolved into a live proof point for the CeDeFi thesis, where institutional capital, retail participation, and real-world financial instruments converge in a single, composable environment.
Record-Breaking Early Momentum for Aave v3 on Mantle
Since launching on Mantle, Aave v3 has onboarded a broad and strategically curated set of assets which includes wETH, USDC, GHO, FBTC, USDe, and wrsETH with additional assets planned for future onboarding subject to governance review. The asset lineup reflects a deliberate focus on both capital efficiency and ecosystem diversity, spanning native stablecoins, liquid staking derivatives, Bitcoin-backed instruments, and yield-bearing tokens.
Each market has been configured with a full suite of per-asset risk parameters, including isolation mode flags, conservative supply and borrow caps, and tailored interest-rate curves, all subject to ongoing review by Aave's risk service providers. This governance-first approach ensures that Mantle's rapid liquidity growth is matched with the institutional-grade safety and transparency that large allocators require.
Key Milestones Since Launch
- $575M+ Total Market Size in Two Weeks: Combined supply and borrow activity across Aave v3 on Mantle has exceeded $575 million indicating a milestone that underscores both the depth of existing demand and the effectiveness of the coordinated incentive framework.
- wrsETH Supply Cap Maxed Twice in One Week: The wrsETH pool by KelpDAO reached its supply cap twice within a single week, with deposits doubling to approximately $50 million within three days — a clear signal of concentrated, high-conviction demand for liquid restaking exposure on Mantle.
- Institutional Capital Participation: The deployment's focus on RWA-compatible infrastructure and institutional-grade risk controls has attracted significant allocations from professional participants seeking capital-efficient, transparent on-chain yield.
- GHO Expansion on Mantle: The deployment of Aave's native stablecoin GHO has established a new liquidity hub on Mantle, supported by active distribution from the Aave Liquidity Committee.
Active Incentive Programs
To reward early adopters and sustain long-term liquidity depth, two coordinated incentive programs are currently live:
- Mantle (MNT) Rewards: A total of 8 million $MNT has been allocated to incentivize suppliers and borrowers across prioritized markets, including ETH, USDC, and USDT.
- Aave DAO Contribution: The Aave Liquidity Committee is distributing 1.5 million $GHO to drive stablecoin adoption and ensure deep liquidity for GHO-based pairs across the Mantle market.
Building the Foundation for CeDeFi at Scale
The Mantle & Aave integration represents more than a protocol deployment. It is a foundational layer for the CeDeFi future. Through its structural alignment with Bybit, Mantle provides a direct bridge for more than 70 million global users to access decentralized markets, with the trust, compliance, and UX expectations of a world-class centralized exchange.
Upcoming phases of the collaboration are designed to deepen this bridge further:
- Integrated Earn Products: Direct integration of Aave's yield-bearing assets into Bybit's Earn suite, enabling seamless access to on-chain yield for Bybit's global user base.
- Advanced Collateral Options: Support for Mantle-native assets and RWA-backed tokens within Aave's isolated pools, unlocking greater capital efficiency for institutional participants.
"Surpassing $575 million in total market size within two weeks is not just a number but a validation that the market has been waiting for infrastructure that connects institutional capital, real-world assets, and decentralized finance without compromise. Mantle was built to be the distribution layer where this convergence happens, and what we're seeing today is exactly that thesis playing out in real time." said Emily Bao, Key Advisor at Mantle.
Start Earning on Mantle
Users can access the Mantle market via the official Aave interface to supply assets, borrow against collateral, and begin earning boosted rewards.
About Mantle
Mantle positions itself as the premier distribution layer and gateway for institutions and TradFi to connect with on-chain liquidity and access real-world assets, powering how real-world finance flows.
With over $4B+ in community-owned assets, Mantle combines credibility, liquidity and scalability with institutional-grade infrastructure to support large-scale adoption. The ecosystem is anchored by $MNT within Bybit, and built out through core ecosystem projects like mETH, fBTC, MI4 and more. This is complemented by Mantle Network's partnerships with leading issuers and protocols such as Ethena USDe, Ondo USDY, and OP-Succinct.
For more information about Mantle, please visit: mantle.xyz
For more social updates, please follow: Mantle Official X & Mantle Community Channel
For media enquiries, please contact: contact@mantle.xyz
About Aave Protocol
Aave is a decentralized, non-custodial liquidity protocol where users can participate as suppliers or borrowers. Suppliers provide liquidity to the market while earning interest, and borrowers can access liquidity by providing collateral that exceeds the borrowed amount. Aave also supports GHO, its decentralized overcollateralized stablecoin, designed to provide transparent, on-chain stable liquidity. With a 60% market share of DeFi lending, Aave is the largest and most trusted on-chain lending network, with over $52B in net deposits.
The Mantle-Aave-Bybit integration delivers record-breaking on-chain liquidity, driven by coordinated incentive programs and deep CeDeFi infrastructure.
DUBAI, UAE, Feb. 25, 2026 /PRNewswire/ -- Following the successful mainnet integration between Mantle and Aave, announced in collaboration with Bybit, Mantle and Aave today announced that their joint deployment has surpassed $575 million in total market size, encompassing both supply and borrows within just two weeks of going live.
The milestone reflects the growing demand for institutional-grade DeFi infrastructure and marks one of the fastest liquidity ramp-ups in Aave's deployment history across any network.
The integration, which brought together Mantle's high-performance distribution layer, Aave's leading decentralized liquidity markets, and Bybit's global exchange infrastructure, has established a unified framework for on-chain finance that bridges centralized and decentralized ecosystems at scale. What began as a protocol deployment has rapidly evolved into a live proof point for the CeDeFi thesis, where institutional capital, retail participation, and real-world financial instruments converge in a single, composable environment.
Record-Breaking Early Momentum for Aave v3 on Mantle
Since launching on Mantle, Aave v3 has onboarded a broad and strategically curated set of assets which includes wETH, USDC, GHO, FBTC, USDe, and wrsETH with additional assets planned for future onboarding subject to governance review. The asset lineup reflects a deliberate focus on both capital efficiency and ecosystem diversity, spanning native stablecoins, liquid staking derivatives, Bitcoin-backed instruments, and yield-bearing tokens.
Each market has been configured with a full suite of per-asset risk parameters, including isolation mode flags, conservative supply and borrow caps, and tailored interest-rate curves, all subject to ongoing review by Aave's risk service providers. This governance-first approach ensures that Mantle's rapid liquidity growth is matched with the institutional-grade safety and transparency that large allocators require.
Key Milestones Since Launch
- $575M+ Total Market Size in Two Weeks: Combined supply and borrow activity across Aave v3 on Mantle has exceeded $575 million indicating a milestone that underscores both the depth of existing demand and the effectiveness of the coordinated incentive framework.
- wrsETH Supply Cap Maxed Twice in One Week: The wrsETH pool by KelpDAO reached its supply cap twice within a single week, with deposits doubling to approximately $50 million within three days — a clear signal of concentrated, high-conviction demand for liquid restaking exposure on Mantle.
- Institutional Capital Participation: The deployment's focus on RWA-compatible infrastructure and institutional-grade risk controls has attracted significant allocations from professional participants seeking capital-efficient, transparent on-chain yield.
- GHO Expansion on Mantle: The deployment of Aave's native stablecoin GHO has established a new liquidity hub on Mantle, supported by active distribution from the Aave Liquidity Committee.
Active Incentive Programs
To reward early adopters and sustain long-term liquidity depth, two coordinated incentive programs are currently live:
Building the Foundation for CeDeFi at Scale
The Mantle & Aave integration represents more than a protocol deployment. It is a foundational layer for the CeDeFi future. Through its structural alignment with Bybit, Mantle provides a direct bridge for more than 70 million global users to access decentralized markets, with the trust, compliance, and UX expectations of a world-class centralized exchange.
Upcoming phases of the collaboration are designed to deepen this bridge further:
- Integrated Earn Products: Direct integration of Aave's yield-bearing assets into Bybit's Earn suite, enabling seamless access to on-chain yield for Bybit's global user base.
- Advanced Collateral Options: Support for Mantle-native assets and RWA-backed tokens within Aave's isolated pools, unlocking greater capital efficiency for institutional participants.
"Surpassing $575 million in total market size within two weeks is not just a number but a validation that the market has been waiting for infrastructure that connects institutional capital, real-world assets, and decentralized finance without compromise. Mantle was built to be the distribution layer where this convergence happens, and what we're seeing today is exactly that thesis playing out in real time." said Emily Bao, Key Advisor at Mantle.
Start Earning on Mantle
Users can access the Mantle market via the official Aave interface to supply assets, borrow against collateral, and begin earning boosted rewards.
About Mantle
Mantle positions itself as the premier distribution layer and gateway for institutions and TradFi to connect with on-chain liquidity and access real-world assets, powering how real-world finance flows.
With over $4B+ in community-owned assets, Mantle combines credibility, liquidity and scalability with institutional-grade infrastructure to support large-scale adoption. The ecosystem is anchored by $MNT within Bybit, and built out through core ecosystem projects like mETH, fBTC, MI4 and more. This is complemented by Mantle Network's partnerships with leading issuers and protocols such as Ethena USDe, Ondo USDY, and OP-Succinct.
For more information about Mantle, please visit: mantle.xyz
For more social updates, please follow: Mantle Official X & Mantle Community Channel
For media enquiries, please contact: contact@mantle.xyz
About Aave Protocol
Aave is a decentralized, non-custodial liquidity protocol where users can participate as suppliers or borrowers. Suppliers provide liquidity to the market while earning interest, and borrowers can access liquidity by providing collateral that exceeds the borrowed amount. Aave also supports GHO, its decentralized overcollateralized stablecoin, designed to provide transparent, on-chain stable liquidity. With a 60% market share of DeFi lending, Aave is the largest and most trusted on-chain lending network, with over $52B in net deposits.
** The press release content is from PR Newswire. Bastille Post is not involved in its creation. **
Mantle and Aave Surpass $575 Million in Total Market Size Within Two Weeks of Launch, Marking a New Benchmark for Institutional DeFi
- TruPath™ Genome offers more complete genome, with the simplest sample to sequencer workflow
- Data presented at AGBT demonstrates TruPath Genome's accuracy in detecting rare genetic disease
- Broad Clinical Labs is among first to adopt product, which was previously known as "constellation mapped read technology"
SAN DIEGO, Feb. 25, 2026 /PRNewswire/ -- Illumina, Inc. (NASDAQ: ILMN) today announced the launch of TruPath™ Genome, setting a new standard for high-quality, comprehensive whole genome insights for genetic disease. TruPath Genome has been found to deliver unparalleled accuracy and resolution—even across so-called "dark regions" of the genome—providing researchers with a more complete picture of genomic alterations implicated in genetic disease.
With an incredibly simple workflow, TruPath Genome eliminates traditional library prep. In about 10 minutes of hands-on time, TruPath Genome generates 16 whole genomes per day, nearly double the throughput of competing long-read methods, and with fewer errors.
TruPath Genome leverages novel on-flow cell library preparation with patterned flow cell technology and advanced informatics to seamlessly add long-distance insights for comprehensive variant detection. DRAGEN™ algorithms tuned to incorporate proximity information from TruPath flow cells improve read alignment and variant calling, extending Illumina high-quality reads to difficult-to-map regions, variant phasing, structural variants, short tandem repeats (STR), and clinically relevant paralogous genes. TruPath Genome fully phases up to 98% of genes.
"With TruPath Genome, we are pushing the boundaries of genomics and setting a new standard for genetic and rare disease research," said Steve Barnard, PhD, chief technology officer of Illumina. "In rare disease, you're often looking for a variant needle in a genomic haystack—and comprehensiveness, accuracy, and confidence matter. This technology unlocks rapid answers to shed light on the genomic drivers of genetic disease with an ease that was never thought possible."
TruPath Genome delivers a highly cost-effective whole genome workflow, at an industry standard depth of at least 30x coverage with single-use flow cell, which is critical in clinical research.
Data presented at AGBT illustrates a short-read path to long-distance insight
Data presented today at AGBT and in previous publications illustrates how TruPath Genome is already shedding light on some of the most challenging genetic diseases, including spinal muscular atrophy, kidney disease, and complex adrenal disorders.
- Researchers at University Medical Center Utrecht presented data evaluating TruPath Genome in challenging rare disease samples, with a particular focus on long–range phasing performance required to support non–invasive prenatal diagnostic (NIPD) assays, as well as resolution of difficult genomic regions and complex structural variants.
SAN DIEGO, Feb. 25, 2026 /PRNewswire/ -- Illumina, Inc. (NASDAQ: ILMN) today announced the launch of TruPath™ Genome, setting a new standard for high-quality, comprehensive whole genome insights for genetic disease. TruPath Genome has been found to deliver unparalleled accuracy and resolution—even across so-called "dark regions" of the genome—providing researchers with a more complete picture of genomic alterations implicated in genetic disease.
With an incredibly simple workflow, TruPath Genome eliminates traditional library prep. In about 10 minutes of hands-on time, TruPath Genome generates 16 whole genomes per day, nearly double the throughput of competing long-read methods, and with fewer errors.
TruPath Genome leverages novel on-flow cell library preparation with patterned flow cell technology and advanced informatics to seamlessly add long-distance insights for comprehensive variant detection. DRAGEN™ algorithms tuned to incorporate proximity information from TruPath flow cells improve read alignment and variant calling, extending Illumina high-quality reads to difficult-to-map regions, variant phasing, structural variants, short tandem repeats (STR), and clinically relevant paralogous genes. TruPath Genome fully phases up to 98% of genes.
"With TruPath Genome, we are pushing the boundaries of genomics and setting a new standard for genetic and rare disease research," said Steve Barnard, PhD, chief technology officer of Illumina. "In rare disease, you're often looking for a variant needle in a genomic haystack—and comprehensiveness, accuracy, and confidence matter. This technology unlocks rapid answers to shed light on the genomic drivers of genetic disease with an ease that was never thought possible."
TruPath Genome delivers a highly cost-effective whole genome workflow, at an industry standard depth of at least 30x coverage with single-use flow cell, which is critical in clinical research.
Data presented at AGBT illustrates a short-read path to long-distance insight
Data presented today at AGBT and in previous publications illustrates how TruPath Genome is already shedding light on some of the most challenging genetic diseases, including spinal muscular atrophy, kidney disease, and complex adrenal disorders.
"TruPath Genome enabled us to consolidate multiple analyses into a single, easy–to–implement whole–genome assay," said Marcel Nelen, PhD, head of the Genome Diagnostic Laboratory at UMC Utrecht. "Despite the simplicity of the workflow, we achieved megabase–scale phasing, full resolution of clinically relevant genes, and improved interpretation of difficult regions—even a particularly challenging case in the notoriously complex SMN1/SMN2 region—as well as complex structural variants. This represents an important step toward a single assay capable of addressing many rare disease research questions without additional orthogonal testing."
- At the recent Festival of Genomics & Biodata in London, researchers from the University of Exeter shared data on their pilot of TruPath Genome, which found that the technology resolved highly complex genomic regions, including a gene known to be associated with inherited adrenal disorders. While current short-read WGS requires parental samples to identify compound heterozygotes, TruPath Genome offers a single-sample path to these insights, improving coverage for samples processed without parental data.
"TruPath Genome opens up a future where every patient affected by a rare genetic condition can receive rapid comprehensive whole-genome testing to end diagnostic odysseys and identify possible precision treatments," said Emma Baple, PhD, professor of Genomic Medicine at the University of Exeter and medical lead for the NHS England Rapid Genome Sequencing Service for Critically Unwell Children. "In Exeter, we have been privileged to evaluate the TruPath technology and seen the potential to change the lives of affected children and their families. We are eager to see how this innovation evolves, as these types of solutions will transform how rare conditions are diagnosed."
Broad Clinical Labs is among the first to adopt TruPath Genome, which will make this important technology available to their collaborators in rare disease research.
"TruPath means a more comprehensive genome to drive our research," said Sean Hofherr, PhD., FACMG, chief of clinical strategy and product development, Broad Clinical Labs. "This technology delivers an impressive ability to interrogate even the most challenging variants in the genome, all in a stunningly simple workflow. And, being able to run it on the NovaSeq X Plus is attractive."
More than 30 early access customers have been piloting the technology over the past 16 months, including GeneDx, Rady Children's Hospital, and Baylor College of Medicine. Baylor College of Medicine recently published a pre-print on the technology in medRxiv.
"We remain committed to advancing the accessibility of genomics through continuous innovation, delivering streamlined end-to-end workflows and comprehensive genomic insights to address the most challenging rare genetic diseases," said Jenny Zheng, Senior Vice President and General Manager of Greater China at Illumina. "In Greater China, we will deepen our collaboration with clinical and research experts to accelerate the transformation of cutting-edge technologies from research into clinical practice, ensuring our innovations truly reach patients. On this occasion of Rare Disease Day, we stand ready to illuminate the path forward for more families navigating the diagnostic odyssey."
The TruPath Genome launch was unveiled today during the Gold Sponsor Workshop at the Advances in Genome Biology and Technology (AGBT) annual meeting in Orlando. Register here for the replay.
TruPath Genome was previously referred to as "constellation mapped read technology." Learn more about TruPath Genome here.
* TruPath Genome carries a list price of $395 USD (exclusive of duties and shipping), including all consumables and analysis.
Use of forward-looking statements
This release may contain forward-looking statements that involve risks and uncertainties. Among the important factors to which our business is subject that could cause actual results to differ materially from those in any forward-looking statements are: (i) challenges inherent in developing and launching new products and services, including modifying and scaling manufacturing operations, and reliance on third-party suppliers for critical components; (ii) our ability to manufacture robust instrumentation and consumables and develop reliable software solutions; and (iii) the acceptance and adoption by customers of our newly launched or updated products, which may or may not meet our and their expectations, together with other factors detailed in our filings with the Securities and Exchange Commission, including our most recent filings on Forms 10-K and 10-Q, or in information disclosed in public conference calls, the date and time of which are released beforehand. We undertake no obligation, and do not intend, to update these forward-looking statements, to review or confirm analysts' expectations, or to provide interim reports or updates on the progress of the current quarter.
About Illumina
Illumina is improving human health by unlocking the power of the genome. Our focus on innovation has established us as a global leader in DNA sequencing and array-based technologies, serving customers in the research, clinical, and applied markets. Our products are used for applications in the life sciences, oncology, reproductive health, agriculture, and other emerging segments. To learn more, visit illumina.com and connect with us on X, Facebook, LinkedIn, Instagram, TikTok, and YouTube.
** The press release content is from PR Newswire. Bastille Post is not involved in its creation. **
Illumina launches TruPath Genome, setting a new standard in genomic insight
