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Biocytogen Enters into Antibody Licensing Agreement with BeOne Medicines to Accelerate Innovative Drug Development

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Biocytogen Enters into Antibody Licensing Agreement with BeOne Medicines to Accelerate Innovative Drug Development
News

News

Biocytogen Enters into Antibody Licensing Agreement with BeOne Medicines to Accelerate Innovative Drug Development

2025-07-10 08:01 Last Updated At:08:10

BEIJING--(BUSINESS WIRE)--Jul 9, 2025--

Biocytogen Pharmaceuticals (Beijing) Co., Ltd. (Biocytogen, HKEX: 02315), a global biotechnology company that drives the research and development of novel antibody-based drugs with innovative technologies, today announced that it has entered into a global licensing agreement with BeOne Medicines Ltd., a global oncology company, for multiple fully human antibodies.

This press release features multimedia. View the full release here: https://www.businesswire.com/news/home/20250709204455/en/

Prior to this licensing agreement, BeOne Medicines had obtained a license to use Biocytogen’s RenMice ® fully human antibody platform. Building on this established collaboration, the new agreement expands the partnership into antibody license, further strengthening the strategic relationship between the two companies.

Dr. Yuelei Shen, President and CEO of Biocytogen, said, “BeOne Medicines is a global leader in drug development, and we are thrilled to enter into this strategic collaboration. The antibodies licensed under this agreement were discovered using our proprietary RenMice ® fully human antibody platform, highlighting our ability to empower partners in driving innovative drug discovery. We look forward to seeing these promising molecules progress rapidly into the clinic and ultimately bring transformative treatment options to patients worldwide.”

Under the terms of the agreement, Biocytogen will receive an upfront payment from BeOne Medicines. In addition, Biocytogen is eligible to receive development and regulatory milestone payments, commercial milestone payments, and tiered royalties based on future net sales of licensed products.

About Biocytogen

Biocytogen (HKEX: 02315) is a global biotechnology company that drives the research and development of novel antibody-based drugs with innovative technologies. Founded on gene editing technology, Biocytogen leverages genetically engineered proprietary RenMice ® (RenMab ™ / RenLite ® / RenNano ® / RenTCR-mimic™) platforms for fully human monoclonal/bispecific/multispecific antibody discovery, bispecific antibody-drug conjugate discovery, nanobody discovery and TCR-mimic antibody discovery, and has established a sub-brand, RenBiologics™, to explore global partnerships for an off-the-shelf library of >1,000,000 fully human antibody sequences against over 1000 targets for worldwide collaboration. As of December 31, 2024, approximately 200 therapeutic antibody and multiple clinical asset co-development/out-licensing/transfer agreements and over 50 target-nominated RenMice ® licensing projects have been established around the globe, including several partnerships with multinational pharmaceutical companies (MNCs). Biocytogen pioneered the generation of drug target knock-in humanized models for preclinical research, and currently provides a few thousand off-the-shelf animal and cell models under the company's sub-brand, BioMice™, along with preclinical pharmacology and gene-editing services for clients worldwide. Headquartered in Beijing, Biocytogen has branches in China (Haimen Jiangsu, Shanghai), USA (Boston, San Francisco, San Diego), and Germany (Heidelberg). For more information, please visit http://en.biocytogen.com.cn.

Biocytogen Enters into Antibody Licensing Agreement with BeOne Medicines to Accelerate Innovative Drug Development

Biocytogen Enters into Antibody Licensing Agreement with BeOne Medicines to Accelerate Innovative Drug Development

SAN DIEGO (AP) — Ty France hit a three-run homer to cap a six-run rally in the fifth inning and the San Diego Padres beat the Miami Marlins 8-2 on Friday night to pull into a tie with Philadelphia and Chicago for the top National League wild card.

The Cubs and Phillies both lost just around first pitch in San Diego. Then the Padres erased a 1-0 deficit to win for the 11th time in 12 games.

Although Chicago, Philadelphia and San Diego are even at 85-69 for the three NL wild cards, the Padres would lose tiebreakers against the Cubs and Phillies in the race for the No. 1 spot and the right to host an opening round. The Cubs beat the Padres 2-1 in the wild-card round in Chicago last season.

Miami (76-78) was eliminated from the postseason race.

France, who signed a minor league deal during spring training, hit the first pitch he saw from reliever Tyler Zuber off the balcony on the third level of the Western Metal Supply Co. brick warehouse in the left-field corner with two outs in the fifth to bring in Fernando Tatis Jr. and Dustin Harris to make it 6-1.

France paused for a moment to watch his career-high 21st homer sail away and then tossed his bat and began his trot. France played at San Diego State for Hall of Famer Tony Gwynn and is in his second stint with the Padres.

Tatis hit an RBI single with the bases loaded and one out, and Harris followed with a two-run single.

Agustín Ramírez, Miami's No. 9 batter, lined a homer off Nick Pivetta into the seats in left field with one out in the third, his fifth.

That was the only big mistake by Pivetta (3-2), who allowed one run and four hits in five innings while striking out four and walking one.

San Diego's Jackson Merrill homered in the eighth, his 26th.

Cade Gibson (5-2) took the loss in relief.

Marlins RHP Eury Pérez (7-11, 3.99 ERA) and Padres RHP Casey Mize (6-9, 3.69) are scheduled to start Saturday night.

See AP’s full MLB coverage here

San Diego Padres' Jackson Merrill celebrates after hitting a home run during the eighth inning of a baseball game against the Miami Marlins Friday, Sept. 18, 2026, in San Diego. (AP Photo/Gregory Bull)

San Diego Padres' Jackson Merrill celebrates after hitting a home run during the eighth inning of a baseball game against the Miami Marlins Friday, Sept. 18, 2026, in San Diego. (AP Photo/Gregory Bull)

San Diego Padres' Jackson Merrill, center, celebrates after hitting a home run during the eighth inning of a baseball game against the Miami Marlins Friday, Sept. 18, 2026, in San Diego. (AP Photo/Gregory Bull)

San Diego Padres' Jackson Merrill, center, celebrates after hitting a home run during the eighth inning of a baseball game against the Miami Marlins Friday, Sept. 18, 2026, in San Diego. (AP Photo/Gregory Bull)

San Diego Padres' Ty France, right, celebrates with Fernando Tatis Jr. after hitting a three-run home run during the fifth inning of a baseball game against the Miami Marlins Friday, Sept. 18, 2026, in San Diego. (AP Photo/Gregory Bull)

San Diego Padres' Ty France, right, celebrates with Fernando Tatis Jr. after hitting a three-run home run during the fifth inning of a baseball game against the Miami Marlins Friday, Sept. 18, 2026, in San Diego. (AP Photo/Gregory Bull)

San Diego Padres' Ty France, right, celebrates with teammate Manny Machado after hitting a three-run home run during the fifth inning of a baseball game against the Miami Marlins Friday, Sept. 18, 2026, in San Diego. (AP Photo/Gregory Bull)

San Diego Padres' Ty France, right, celebrates with teammate Manny Machado after hitting a three-run home run during the fifth inning of a baseball game against the Miami Marlins Friday, Sept. 18, 2026, in San Diego. (AP Photo/Gregory Bull)

San Diego Padres' Ty France celebrates after hitting a three-run home run during the fifth inning of a baseball game against the Miami Marlins Friday, Sept. 18, 2026, in San Diego. (AP Photo/Gregory Bull)

San Diego Padres' Ty France celebrates after hitting a three-run home run during the fifth inning of a baseball game against the Miami Marlins Friday, Sept. 18, 2026, in San Diego. (AP Photo/Gregory Bull)

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