WILMINGTON, Del.--(BUSINESS WIRE)--Feb 5, 2026--
AOP Health US, LLC announced today that Rapiblyk® (landiolol) is now more widely available across the United States through contract with Vizient®, the nation’s largest provider-driven healthcare performance improvement company. Hospitals and health systems nationwide now have increased access through the Vizient catalog to Rapiblyk®, enhancing flexibility while expanding the availability of this critical care therapy.
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Furthermore, through the Vizient contract, participating hospital clients may have enhanced access to tiered pricing and streamlined ordering.
“This represents an important milestone in ensuring that Rapiblyk availability is secured nationwide, supporting clinicians and healthcare providers in critical care environments,” said John Kimmet,General Manager of AOP Health US. “We’re reinforcing our commitment to making Rapiblyk accessible where it’s needed most.”
AOP Health US previously announced the U.S. commercial availability of Rapiblyk® (landiolol), an ultra-short-acting, selective beta-1 adrenergic receptor blocker approved by the U.S. Food and Drug Administration (FDA) for the short-term reduction of ventricular rate in adults with supraventricular tachycardia (SVT) or irregular rapid heart rate, including atrial fibrillation and atrial flutter, in critical care settings
Prescribing information can be found at www.rapiblyk.com
About Rapiblyk®
Rapiblyk® (landiolol) is an ultra-short-acting, selective beta-1 adrenergic receptor blocker indicated for the short-term reduction of ventricular rate in adults with supraventricular tachycardia (SVT) or irregular rapid heart rate, including atrial fibrillation and atrial flutter, especially in perioperative, postoperative, or critical-care settings. Rapiblyk® provides rapid onset and offset of action, allowing clinicians to achieve precise, controlled rate management with a favorable hemodynamic profile.
The product is supplied as an intravenous infusion designed for use in a monitored hospital setting.
INDICATION
Rapiblyk® is indicated for the short-term reduction of ventricular rate in adults with supraventricular tachycardia, including atrial fibrillation and atrial flutter.
IMPORTANT SAFETY INFORMATION
CONTRAINDICATIONS
Rapiblyk® is contraindicated in patients with:
WARNINGS AND PRECAUTIONS
Includes risk of hypotension, bradycardia, cardiac failure, bronchospasm, masking of hypoglycemia symptoms, infusion site reactions, worsening of Prinzmetal’s angina, complications in pheochromocytoma, peripheral vascular disease, abrupt withdrawal effects, hyperkalemia, metabolic acidosis, and unresponsiveness to epinephrine in hypersensitivity reactions.
ADVERSE REACTIONS
Most important and common adverse reaction is hypotension which in clinical trials occurred in 9.9% of patients receiving RAPIBLYK® vs. 1% in those receiving placebo. Please consult the full Prescribing Information for Rapiblyk®: https://www.accessdata.fda.gov/drugsatfda_docs/label/2024/217202s000lbl.pdf
About AOP Health
AOP Health is a global enterprise with roots in Austria and a mission to address unmet medical needs through innovative, science-driven therapies in cardiovascular and rare disease. Since 1996, the AOP Health Group has been recognized as a pioneer in developing integrated therapy solutions that combine deep scientific expertise with a strong commitment to patient and physician needs.
Building on this foundation, AOP Health US, LLC was established in 2025 to expand the company’s impact in the United States. The team is focused on introducing its 2024 US FDA approved product for use in the critical care setting, while building the infrastructure to support healthcare professionals and the patients they serve.
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NEW YORK (AP) — Dropping technology stocks are dragging the U.S. market lower again on Thursday, while prices for bitcoin, silver and gold fall sharply. Yields are also sinking in the bond market following discouraging news on the U.S. job market.
The S&P 500 fell 0.8% and is heading toward its sixth loss in the seven days since it set an all-time high. The Dow Jones Industrial Average was down 326 points, or 0.7%, as of 9:35 a.m. Eastern time, and the Nasdaq composite was 0.8% lower.
Alphabet helped drag the market lower by sinking 5.4%, even though the parent company of Google reported a stronger profit for the latest quarter than analysts expected. Investors focused instead on how much Alphabet is spending on artificial-intelligence technology and questioned whether it will all prove worth it.
Alphabet said its spending on equipment and other investments could double this year to roughly $180 billion. That blew past analysts’ expectations of less than $119 billion, according to FactSet.
In the bond market, Treasury yields sank after a report said the number of U.S. workers applying for unemployment benefits jumped last week by more than economists expected. That could be a signal that the pace of layoffs is accelerating.
Some economists suggested last week’s rise could be statistical noise, and the total number remains relatively low compared with history. But a separate report released in the morning said that layoffs announced by U.S.-based employers surged last month. The 108,435 was the highest number for a month since October, according to global outplacement and executive coaching firm Challenger, Gray & Christmas. For a January, it’s the worst since 2009.
Weakness in the job market could push the Federal Reserve to cut interest rates to support the economy, even if it also risks worsening inflation. Treasury yields fell across the board in response.
The yield on the 10-year Treasury sank to 4.23% from 4.29% late Wednesday.
The moves were even sharper in commodities markets.
Silver’s price tumbled 12.1% in its latest wild swing since its record-breaking momentum suddenly halted last week.
Gold’s price fell 1.9% to $4,855.00 per ounce. It’s been careening back and forth since it roughly doubled in price over 12 months. It neared $5,600 last week and then fell below $4,500 on Monday.
Both gold and silver had been screaming higher as investors piled into places they thought would be safer amid worries about political turmoil, a U.S. stock market that critics called expensive and huge debt loads for governments worldwide. But nothing can keep rising at such extreme rates forever, and critics had been calling for a pullback.
Bitcoin, which is pitched as the “digital gold,” also sank. It briefly dropped below $70,000, down from its record above $124,000 set in October.
On Wall Street, Qualcomm fell 9.1% even though the chip company topped analysts’ expectations for profit and revenue in the latest quarter. Its forecast for profit in the current quarter fell short of analysts’ expectations as an industrywide shortage of memory pushes some handset makers to cut back on orders.
Outside of tech, Estee Lauder also topped Wall Street targets but said it expects tariff-related headwinds to wipe out about $100 million worth of profits in its fiscal year. The New York cosmetic company’s shares sank 16.9%.
In stock markets abroad, indexes fell across much of Europe and Asia.
London’s FTSE 100 fell 0.9% after the Bank of England held interest rates there steady. France’s CAC 40 fell 0.6%, and Germany’s DAX lost 1.1% after the European Central Bank likewise stood pat on interest rates.
South Korea’s Kospi tumbled 3.9% for one of the world’s biggest moves and dropped from its all-time high. Samsung Electronics dropped 6%, just two days after it had surged 11.4%.
AP Business Writers Matt Ott and Elaine Kurtenbach contributed.
Trader Joseph Stevens, foreground, works with colleagues on the floor of the New York Stock Exchange, Tuesday, Feb. 3, 2026. (AP Photo/Richard Drew)
Currency traders watch monitors near a screen showing the Korea Composite Stock Price Index (KOSPI), top right, at the foreign exchange dealing room of the Hana Bank headquarters in Seoul, South Korea, Monday, Feb. 2, 2026. (AP Photo/Ahn Young-joon)
A currency traders watches monitors near a screen showing the Korea Composite Stock Price Index (KOSPI), left, at the foreign exchange dealing room of the Hana Bank headquarters in Seoul, South Korea, Monday, Feb. 2, 2026. (AP Photo/Ahn Young-joon)
A board above the trading floor of the New York Stock Exchange displays the closing number for the Dow Jones industrial average, Monday, Feb. 2, 2026. (AP Photo/Richard Drew)
Specialist Anthony Matesic works at his post on the floor of the New York Stock Exchange, Monday, Feb. 2, 2026. (AP Photo/Richard Drew)
