Humanized mice, mpox testing kits, and a way of finding out if you are going to have a heart attack 720 days in advance.
Those are just a few of the breakthroughs scientists showed off at BIOHK 2024, an international gathering of bio-tech experts in Hong Kong—and we'll discuss some of them shortly.
But first, the really big news came in the opening event, when speakers noted the sheer number of biotech companies in the Greater Bay Area.
China has 199 science parks, with 111 featuring biotechnology research and development. Of those, 93 are concentrated in Greater Bay Area. Thus it appears inevitable that this region will be a biotech center for the world.
"I believe that you are building here a unique confluence of biomed research and analytics that not just as the opportunity to serve China but it also has the opportunity to serve the rest of the world because these are unique components that so few parts of the world have," said Sir Jonathan Symonds, chairman of GSK, one of the world's biggest healthcare firms.
Businesses agree with him. More than 60 companies have already signed up to participate in the Hong Kong Shenzhen Innovation and Technology Park.
And where will the money come from? Hong Kong is already one of the largest global biotech fundraising hubs in the world, so has plenty of skill in organizing investments.
There are large numbers of companies at this event, with a great many breakthroughs to show off, but let's look in more detail at a few.
HUMANIZED MICE
First, consider a problem. Before potentially dangerous medical products are used on you or your children, they are tested on mice. But there are a great many differences between rodents and humans.
So Chinese scientists are putting specific genes into mice to bridge that gap for specific experiments. These are known as humanized mice.
Mingceler, a firm based in Guangzhou, has developed what it calls Turbo Mice, accelerated rodents which provide genetic material for checking drugs are safe in half the normal development time.
PREDICTING YOUR FUTURE
Then there's this firm, BSP Medical, which has developed a test that can check if you are likely to have a heart attack, 720 days before it happens. Long enough, the theory goes, for you to develop healthy habits to change the future.
There were also food labels that change color when the food goes bad, artificial mussels that detect pollutants in the water, and a phone app that tells you how many calories in your lunch—and advises you on healthy restaurants near you.
These are all fun developments, but there's a serious message behind all this. The proportion of old people in the world is rising fast and there simply won't be enough money in the system to give people the care they need, unless things change rapidly.
Here's what Sir Jonathan Symonds said: "So I congratulate you, I commend you and I urge you to continue to move at pace because I think you have a significant contribution to make to the health of the world."
by Nury Vittachi
Lai See(利是)
** 博客文章文責自負,不代表本公司立場 **
A White Booster Fragment Reopens an Old Mystery
A chunk of ballistic missile booster debris appeared in the Raghwan area of northern Marib Governorate, Yemen on September 14.
Images show the missile body painted an unusual white and marked with “DF-15A.” Its structure and dimensions point to China's DF-15 short-range ballistic missile.
Open-source defense analysts read that as a likely Saudi missile fired at a Houthi target inside Yemen.
For now, the available evidence is just a few social media photos. Saudi Arabia has not confirmed it, and no authoritative third-party institution has verified it.
DF-15A debris in Yemen—fired from a Saudi base?
The DF-15 is a mature single-stage solid-fuel tactical ballistic missile made by China.
It is about 9.1 meters long and 1 meter in diameter, with a total weight of 6.2 tons. Its maximum range is 600 kilometers, and it can carry a warhead of nearly 1 ton.
It uses a wheeled high-mobility launch vehicle and has a rapid-response capability of “stop and launch.”
For more than a year, outsiders have speculated whether Saudi Arabia possesses the DF-15.
Yoel Guzansky, a scholar at an Israeli think tank, has analyzed the question. He argues that while the Royal Saudi Strategic Missile Force introduced long-range deterrence, it very likely secretly procured short-range ballistic missiles such as the DF-15 to build a layered strike capability.
Then there is the 2013 model. When Prince Fahd, then Saudi Deputy Defense Minister, visited the Strategic Missile Force headquarters, the commemorative model he received showed three missiles side by side. Many at the time speculated they corresponded to the DF-15, DF-21, and the older DF-3.
Those early details are now being raised again because of the debris on the Yemen battlefield.
A gift model fueled years of DF-15 speculation.
Saudi Arabia's ballistic missile dealings with China go back to the 1980s. During the Iran-Iraq War, the “War of the Cities” missile attacks made Saudi Arabia feel security pressure.
In 1987, the two sides reached a defense project codenamed “Golden Wheel Project.” Saudi Arabia imported the DF-3 medium-range liquid-fuel ballistic missile and used it to build the Royal Saudi Strategic Missile Force, independent of the army, navy, and air force.
The liquid-fueled DF-3 required long preparation time and complex maintenance, with obvious operational limitations. After 2000, Saudi Arabia has introduced the DF-21B solid-fuel medium-range ballistic missile, with a range close to 2,000 kilometers and markedly improved strike accuracy.
If the DF-15 was indeed among the purchases, its timing would roughly fall between the two.
So why use missiles in Yemen instead of sending aircraft?
Why Jets Alone No Longer Solve the Problem
Saudi Arabia has one of the largest air forces in the Middle East. Its F-15SA and Typhoon fleets together number in the hundreds, and their payload capacity and precision-guided strike capability are first-rate. Two F-15s carrying several tons of precision-guided bombs usually deliver more against a target inside Yemen than a single DF-15A with a warhead of less than half a ton. On pure strike efficiency, the aircraft should be the first choice. The problem isn't the aircraft. It's the conditions needed to keep them flying sortie after sortie.
A modern air force cannot be made operational simply by buying a few fighter jets. Behind a single F-15 sortie is an entire chain: secure bases, intact runways, aviation fuel, ammunition depots, maintenance personnel, spare parts supply, and aerial refueling formations. If any link in that chain is continuously disrupted, the number of aircraft on paper separates from the number of sorties that can actually be flown each day.
The Houthis have built their recent tactics around exactly this logistics chain. On September 8, they said they used missiles and drones to hit King Khalid Air Base, Saudi Aramco oil facilities near Abha, and multiple targets in Jizan and Najran. Saudi authorities later confirmed attacks in several locations and said there were injuries.
By September 14, the Houthis again claimed to have struck hangars, radar, runways, and ammunition depots at Khamis Mushait Air Base. None of these targets were frontline positions. They were the core logistical hubs for Saudi air force operations, and the Houthi aim was to directly degrade the ability of Saudi warplanes to sustain sortie generation.
For Saudi air force planners, this means a higher cost per sortie. In the past, an F-15 taking off from Khamis Mushait had a very short flight to target areas in Yemen and could fly multiple waves in a day. The base can still be used now. But before each sortie, more time must be spent assessing runway safety, ammunition stocks, and fuel reserves. If missions are pulled back to Taif or even bases in central Saudi Arabia, the distance to Yemen nearly doubles, dependence on aerial refueling increases sharply, and the number of daily sorties from the same aircraft fleet declines.
In this context, ballistic missiles become far more attractive. They do not need runways, pilots, or tanker aircraft. They do not consume sortie capacity at harassed forward bases, and they do not expend U.S.-provided precision-guided bombs. With solid-fuel propulsion and pre-set parameters on mobile launchers, they can hit targets directly from several hundred kilometers away.
Truck-mounted missiles strike fast—no air bases needed
A Two-Tier Strike System Takes Shape
The DF-15A is a short-range ballistic missile that China finalized in the 1990s and brought to the international market in the 2000s. It is not cutting-edge by today's standards, but its attributes strike at Saudi Arabia's current pain points.
It also has shortcomings. It is not cost-effective against moving targets, costs more than a conventional airstrike, and is less accurate than laser-guided bombs. So it will not replace aircraft. Instead, it backfills specific scenarios: striking fixed command posts, frontline assembly areas, storage facilities, or conducting high-intensity area denial as the Houthis advance.
If the reports are true, what is Saudi Arabia trying to convey by using the DF-15? It does not look like a gesture aimed solely at Iran. Iran does not need a piece of wreckage to confirm that Saudi Arabia has ballistic missiles.
Nor does it necessarily mean Saudi Arabia is short of warplanes. Saudi Arabia still maintains hundreds of advanced fighter jets, and its force structure has not changed. What is really being tested is the sortie rate of frontline aircraft and persistently high combat costs.
The signal truly worth noting is that Saudi Arabia is adjusting its strike system. It is moving from an air-heavy approach to a two-tier structure of 'air plus ballistic missiles.'
When the air chain is functioning normally, F-15s and Typhoons carry the main precision-strike burden. When bases are disrupted, fuel is tight, precision munitions must be conserved, and the cost of forward sorties is too high, ballistic missiles take over some conventional missions.
This is an adjustment made under battlefield pressure by a military of considerable size. It is not a sign of desperation.
This piece of wreckage on the battlefield in northern Yemen, whether or not it is ultimately confirmed, has already put a question on the table. When ballistic missiles move from the strategic deterrence arsenal into the conventional strike sequence, it shows that battlefield friction has become large enough to change a country's approach to striking.
If this wreckage is ultimately confirmed, it would also mean another thing: a Chinese-developed DF-series ballistic missile has left a record of actual combat use for the first time.
Since the DF-3 was exported to Saudi Arabia in 1987, the series has for decades been synonymous with strategic deterrence. Its purpose has been 'to keep others from acting' rather than 'to be fired.'
For more than thirty years, it has never truly fallen on a battlefield.
The First Combat Mark, and Why Caution Still Matters
This time, the difference is in kind. Moving the missile from the strategic deterrence stockpile into the conventional strike sequence turns it from a showpiece trump card into an expendable combat asset.
Once that threshold is crossed, the positioning that follows will shift too, but overselling its significance should be cautioned. A short-range ballistic missile hitting a staging area in northern Yemen has limited tactical value. It cannot change the course of the battlefield.
What has truly changed is how the outside world sees China's exported ballistic missiles. In the past, their capabilities stayed mostly on specification sheets and parade grounds. Now battlefield data exists, whether good or bad, and it becomes a verifiable reference in the international arms trade market.
Until the evidence firms up, the phrase "the world's first combat use" still calls for caution. The rare white missile body may indicate something, but it cannot indicate everything.
