加州聖馬刁--(BUSINESS WIRE)--六月 4, 2026--
(美國商業資訊)-- 今日發表於 《通訊醫學》（Communications Medicine） 上的一項初步研究表明，對於有效治療手段極為有限的神經性厭食症，一種新療法有望實現突破。這項來自美國加州大學聖地牙哥分校醫學院的研究報告稱，生酮飲食干預（一種高脂肪、低碳水化合物、中等蛋白質的飲食）對體重正常或輕度偏瘦的神經性厭食症患者而言可行且安全。參與者對生酮飲食干預的耐受性良好，依從性高，且在整個治療過程中未觀察到明顯的體重下降。此外，患者的飲食障礙症狀也得到了顯著改善，近四分之三完成療程的患者在研究結束時成功達到康復標準，所有完成療程的患者的抑鬱評分均有所降低。
本新聞稿包含多媒體資訊。完整新聞稿請見此： https://www.businesswire.com/news/home/20260603386071/zh-HK/
神經性厭食症是一種極具破壞性的精神疾病， 其死亡率在所有精神疾病中名列前茅 。 在美國，平均每52分鐘就有一人因該疾病或相關併發症死亡 。即便患者體重恢復，仍常受到持續性心理症狀的困擾，包括身材焦慮、對進食的強烈恐懼以及對體型的過度關注，導致復發率極高。
加州大學聖地牙哥分校醫學院精神病學教授、該研究負責人、醫學博士Guido Frank曾從事厭食症患者的研究和治療超過25年，他發起這項研究旨在為這一高風險族群拓展治療選項。Frank博士表示：「我們迫切需要新方法來治療神經性厭食症。我們在生酮療法方面的研究不僅著眼於標準療法，更可能深入探討該疾病的潛在生理機制。越來越多的 證據 表明，神經性厭食症與神經代謝功能障礙有關，我們希望直接的代謝干預能夠調節神經功能，並緩解患者的心理症狀。」
這項門診、全國性、單臂臨床研究實施了一項為期14週的受監督的生酮療法干預，在22名入組受試者中，有18名（82%）完成了研究。在整個研究期間，受試者的體重（以BMI衡量）未有顯著變化。研究結束時，根據《進食障礙檢查問卷》（EDE-Q）及《進食障礙量表-3》（EDI-3）的測量結果，在完成研究的受試者中，有72%的人的進食障礙症狀已達康復範圍；並根據《貝克憂鬱量表》（BDI）的測量標準，所有受試者的憂鬱症評分均有所改善，其中72%處於正常範圍內。
共同作者醫學博士Barbara Scolnick是一位任職於麻薩諸塞州瓦班的內科醫師，對她而言，這項研究是她長達十年的個人探索之旅的結晶。「這項研究的科學探索，最初是為了我的姪女Caroline Beckwith尋求療法。」Scolnick醫師分享道，「生酮療法作為癲癇治療的標準療法，在結合其他干預措施後，成為關鍵的催化劑，讓Caroline在與神經性厭食症抗爭15年後終於得到緩解。這些初步研究結果令我深受鼓舞，顯示了這項治療或許能為像Caroline一樣的患者開闢新的治療途徑。」
儘管作者承認，針對此類患者群體實施飲食干預存在臨床上的敏感性，但該研究建立在 先前 的 初步證據 之上，為此提供了概念驗證。研究結果表明，在專業醫療監督和訓練有素的支援下，生酮療法對那些對傳統療法無效的患者俱有潛在療效。
「這項研究凸顯了針對調節潛在神經代謝功能進行飲食干預的潛力，即使對於像神經性厭食症這類最難治癒的精神疾病亦然。」資助這項研究的Baszucki Group共同創辦人暨總裁Jan Ellison Baszucki表示，「我們希望這項研究能夠提高公眾對生酮療法在飲食失調治療中的應用和研究的認識和支持，為患者及其家人帶來新的希望。」
目前，一項針對同時患有神經性厭食症和神經性貪食症患者的擴展研究正在進行中，並在全國招募參與者。有興趣瞭解更多資訊或加入研究的人士，可造訪 研究網站 ，以獲取更多詳情。
關於Baszucki Group
Baszucki Group 由Roblox創辦人兼執行長David Baszucki和暢銷書作家Jan Ellison Baszucki創立於2021年。該集團利用私人捐贈、影響力投資、宣傳宣導、故事講述和社群建構等方式在科學、醫學、農業、食品及生態環境系統領域推動根本性變革。Baszucki Group的主要目標是透過支持代謝、精神病學和神經科學交叉領域的研究活動來改善心理健康。如欲進一步瞭解精神障礙以及腦部健康的代謝治療方法，包括生酮療法，請造訪Baszucki Group的非營利性計畫 Metabolic Mind 。
免責聲明：本公告之原文版本乃官方授權版本。譯文僅供方便瞭解之用，煩請參照原文，原文版本乃唯一具法律效力之版本。
請前往 businesswire.com 瀏覽源版本:https://www.businesswire.com/news/home/20260603386071/zh-HK/
Baszucki Group媒體聯繫：media@baszuckigroup.org
KEYWORD: CALIFORNIA UNITED STATES NORTH AMERICA
INDUSTRY KEYWORD: MENTAL HEALTH HEALTH FITNESS & NUTRITION CLINICAL TRIALS RESEARCH SCIENCE
SOURCE: Baszucki Group
Copyright Business Wire 2026.
PUB: 06/04/2026 01:01 PM/DISC: 06/04/2026 01:02 PM
http://www.businesswire.com/news/home/20260603386071/zh
新研究證明生酮療法為體重正常的神經性厭食症患者帶來希望
BRUSSELS (AP) — With underwater drones and ocean-focused satellites, the EU is expanding its monitoring network of Earth’s seas as climate change fuels heat waves and stronger storms and the Trump administration plans severe cuts to a similar system in the United States.
With an investment package of 92 million euros ($107 million) called OceanEye announced on Wednesday, the EU will be able to take the helm of global efforts to explore the depths of the planet's vast oceans, said Ursula von der Leyen, president of the European Commission.
Oceans are vital ecosystems covering about 70% of planet Earth, hosting complex webs of life that generate oxygen and absorb greenhouse gases like carbon dioxide. Temperatures have risen in oceans faster due to climate change, super-charging storms and drought, ravaging coral reefs across the world, and endangering species in tandem with overfishing and industrial pollution.
Scientists estimate climate change will increase the strength of heat waves and severe storms across Europe.
Monitoring the ocean can help protect it by showing damage and threats to ecosystems that help inform regulations aimed at preventing species loss.
“This is about using science and good governance to understand our ocean and secure our future,” von der Leyen said.
In May, officials in the U.S. began signaling plans to gut its Ocean Observatories Initiative — a network of more than 900 ocean sensors built at a cost of $386 million that has continuously collected real-time data for more than a decade.
Funded by the National Science Foundation, the observatories have tracked everything from ocean circulation and marine ecosystems to climate change and extreme weather. Its data has been freely available and has informed more than 500 scientific publications. The project was slated to run for another 15 to 20 years.
The EU investment was already in the pipeline when the U.S. cuts were announced.
International efforts are organized through the Global Ocean Observing System. The U.S. collects more than half of this data while Europe does about a quarter, followed by Japan, Australia, India and China.
“Europe needs to do more,” said Pierre-Yves Le Traon, an oceanographer and scientific director of the Mercator Ocean International based in Toulouse, France.
By 2035, the EU hopes to cover 35% of Earth’s maritime monitoring network and become the globe’s leading provider of “ocean intelligence.”
Robotic sensors in underwater and in orbit feed information to organizations like shipping companies, fisheries, emergency services and research institutions like the Mercator Ocean Institute that is building a virtual-reality mockup of Earth’s oceans to be updated in real time called the Digital Twin Ocean.
That data is crucial to understanding and adapting to climate change and to a vast array of industries on land and at sea like aquaculture, shipping especially through icy waters, coastal tourism, agriculture and even navies, Le Traon said.
“Knowledge is essential if we want to manage the ocean," Le Traon said. "We really have to be very active for the monitoring and protecting of the ocean because the ocean matters to everyone: for life at sea, for life on Earth.”
Odran Corcoran, a policy advisor for Oceana, said that only by collecting data out of the depths of the still relatively unknown ocean can lawmakers use data to regulate the management of fisheries, marine protection and restoration projects.
“Europe does not just need more ocean data; it needs data that closes biodiversity and seabed knowledge gaps," Corcoran said.
The EU funds will go toward private incubators for oceanic technology and beefing up existing institutions like the Global Ocean Observing System.
Out of the 27 EU nations, 22 have coasts along the Baltic Sea, the Atlantic Ocean, the Black Sea and the Mediterranean. France boasts the bloc’s largest ocean-focused scientific institutions as well as huge maritime borders with overseas territories from Reunion in the Indian Ocean to Saint Martin in the Caribbean.
This story corrects a previous version that stated Reunion is in the Pacific Ocean. It is in the Indian Ocean.
The Associated Press receives support from the Walton Family Foundation for coverage of water and environmental policy. The AP is solely responsible for all content. For all of AP’s environmental coverage, visit https://apnews.com/hub/climate-and-environment
FILE - Strong winds blow in the town of La Plaine Saint-Paul on the French Indian Ocean island of Reunion, Jan. 15, 2024. (AP Photo/Lewis Joly, File)
